Category: Health News

Guselkumab and Golimumab: Better Together for Ulcerative Colitis

CHARLOTTE, NC — People with moderate-to-severe ulcerative colitis benefit from stronger treatment from the start — a combination of monoclonal antibodies — compared with induction with either agent alone, a new phase 2a study demonstrates. Researchers compared the combination therapy of guselkumab and golimumab (both from Janssen) for 12 weeks, followed by guselkumab monotherapy up

Yes, people with autism have empathy

A research group led by Ben-Gurion University of the Negev has proposed a new concept for predicting autism and autistic traits. “Empathic disequilibrium” combines two types of empathy into a single scale for the first time. Their findings were published recently in Autism Research. Cognitive empathy means the ability to recognize other people’s mental states.

Ebola infects 6 schoolkids in Uganda as contagion fear grows

Six schoolchildren in Uganda’s capital have tested positive for Ebola, the health minister said Wednesday, marking a serious escalation of the outbreak declared just over a month ago. The children, who attend three different schools in Kampala, are among at least 15 people in the city confirmed to have been infected with Ebola, according to

Swine acute diarrhea syndrome coronavirus promotes replication by inducing autophagy

A recent iScience study finds that the swine acute diarrhea syndrome coronavirus (SADS-CoV) promotes autophagy to maintain its replication inside host cells. More specifically, the virus downregulates AKT/ mammalian target of rapamycin (mTOR) pathway to induce autophagy. Study: Swine Acute Diarrhea Syndrome Coronavirus Induces Autophagy to Promote Its Replication via the Akt/mTOR Pathway. Image Credit: Kateryna

Is COVID Becoming More Predictable?

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. It’s been nearly a year since a new variant of COVID-19 has been named, leading some to wonder whether the virus is evolving in the same way as it once was. NPR asked a dozen scientists whether the virus was stabilizing,

Diazepam Nasal Spray Effective in Lennox-Gastaut Syndrome

CINCINNATI — A new analysis of data from a phase 3 clinical trial suggests that an inhaled diazepam nasal spray (Valtoco, Neurelis Inc.) works about as well among patients with Lennox-Gastaut Syndrome (LGS) as it does with other patients with pediatric encephalopathies. LGS is a severe form of epilepsy that generally begins in early childhood and has

Psychosis and Dementia; Apps for Stroke Care; and Strange Diseases

Psychosis Linked to Higher Dementia Risk People with psychotic disorders develop dementia at more than twice the rate of those without such disorders do, a new meta-analysis finds. Different psychotic disorders mean a 2.5-fold higher risk for dementia later in life, regardless of the age at which such mental illness develops, according to a review

Discovery could affect the search for new Alzheimer's drugs

Alzheimer's disease is associated with a reduction of insulin receptors in brain microvessels, which may contribute to brain insulin resistance and the formation of amyloid plaques, one of the disease's hallmarks. That's according to a study published today in scientific journal Brain by a team from Université Laval and Rush University Medical Center in Chicago.

Effectiveness of antipsychotics dips for women after age 45 years, says study

Antipsychotic effectiveness declines in women after the age of 45 years, according to a study published online Oct. 5 in Schizophrenia Bulletin. Iris E. Sommer, M.D., Ph.D., from the University Medical Center Groningen in the Netherlands, and colleagues used Finnish nationwide registers (61,889 individuals) to identify persons with schizophrenia/schizoaffective disorder and stratify by sex and

Flu hospitalisations ‘rising fastest in children under 5’

BioNTech's co-founders discuss their cancer vaccine We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info Data suggests the sixth wave of COVID-19 has peaked

Study shows hybrid immunity or vaccine boosters elicit plasma neutralizing activity against Omicron sublineages

In a recent study published in Science, researchers evaluated imprinted antibody responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages. Study: Imprinted antibody responses against SARS-CoV-2 Omicron sublineages. Image Credit: iunewind/Shutterstock Background SARS-CoV-2 Omicron sublineages represent an antigenic shift. They harbor unique spike (S) mutations that facilitate their escape from neutralizing antibodies (nAbs)

Rhinorrhoea is ‘top’ Covid symptom in double jabbed

Sir David Jason says he had ‘seriously bad’ Covid We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info Covid cases have been surging once

Fully vaccinated U.S. frontline workers may experience reduced severity, duration, and viral shedding during SARS-CoV-2

In a recent study published in the Journal of the American Medical Association, researchers investigated the association between two or three doses of the messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccine and viral loads and symptoms during infections with different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. Study: Association of mRNA Vaccination