CHARLOTTE, NC — People with moderate-to-severe ulcerative colitis benefit from stronger treatment from the start — a combination of monoclonal antibodies — compared with induction with either agent alone, a new phase 2a study demonstrates. Researchers compared the combination therapy of guselkumab and golimumab (both from Janssen) for 12 weeks, followed by guselkumab monotherapy up
A research group led by Ben-Gurion University of the Negev has proposed a new concept for predicting autism and autistic traits. “Empathic disequilibrium” combines two types of empathy into a single scale for the first time. Their findings were published recently in Autism Research. Cognitive empathy means the ability to recognize other people’s mental states.
Autistic people are more vulnerable to depression and anxiety during pregnancy, according to new research from the University of Cambridge. The results are published in the Journal of Autism and Developmental Disorders and have important implications for supporting autistic people during pregnancy. In the study, led by researchers at the Autism Research Centre, 524 non-autistic
Improving knowledge of Schaaf-Yang syndrome (SYS), an ultra-rare disease caused by mutations in the MAGEL2 gene, is the aim of the first clinical guideline aimed at health care professionals and families of children affected by it. The article, published in the Journal of Medical Genetics, has revealed the effects of the truncated MAGEL2 protein on
Six schoolchildren in Uganda’s capital have tested positive for Ebola, the health minister said Wednesday, marking a serious escalation of the outbreak declared just over a month ago. The children, who attend three different schools in Kampala, are among at least 15 people in the city confirmed to have been infected with Ebola, according to
A recent iScience study finds that the swine acute diarrhea syndrome coronavirus (SADS-CoV) promotes autophagy to maintain its replication inside host cells. More specifically, the virus downregulates AKT/ mammalian target of rapamycin (mTOR) pathway to induce autophagy. Study: Swine Acute Diarrhea Syndrome Coronavirus Induces Autophagy to Promote Its Replication via the Akt/mTOR Pathway. Image Credit: Kateryna
This article contains affiliate links. We will earn a small commission on purchases made through one of these links but this never influences our experts’ opinions. Products are tested and reviewed independently of commercial initiatives. Blame the weather, blame the diminishing sunlight, but at this time of year, you’ll often notice yourself starting to feel
Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. It’s been nearly a year since a new variant of COVID-19 has been named, leading some to wonder whether the virus is evolving in the same way as it once was. NPR asked a dozen scientists whether the virus was stabilizing,
Varicella vaccination resulted in a 99 percent reduction in the incidence of varicella among persons aged younger than 20 years, according to a study presented at the annual meeting of the Infectious Diseases Society of America (IDWeek), held from Oct. 19 to 23 in Washington, D.C. Mona Marin, M.D., from the U.S. Centers for Disease
CINCINNATI — A new analysis of data from a phase 3 clinical trial suggests that an inhaled diazepam nasal spray (Valtoco, Neurelis Inc.) works about as well among patients with Lennox-Gastaut Syndrome (LGS) as it does with other patients with pediatric encephalopathies. LGS is a severe form of epilepsy that generally begins in early childhood and has
Psychosis Linked to Higher Dementia Risk People with psychotic disorders develop dementia at more than twice the rate of those without such disorders do, a new meta-analysis finds. Different psychotic disorders mean a 2.5-fold higher risk for dementia later in life, regardless of the age at which such mental illness develops, according to a review
Alzheimer's disease is associated with a reduction of insulin receptors in brain microvessels, which may contribute to brain insulin resistance and the formation of amyloid plaques, one of the disease's hallmarks. That's according to a study published today in scientific journal Brain by a team from Université Laval and Rush University Medical Center in Chicago.
Ever had one of those moments when a stressful thought creeps into your mind and suddenly you can’t think of anything else? For some, anxiety is fleeting and part of everyday life. But for those with an anxiety disorder, persistent feelings of fear, dread or uneasiness about something in the future can be debilitating. “Grounding”
Antipsychotic effectiveness declines in women after the age of 45 years, according to a study published online Oct. 5 in Schizophrenia Bulletin. Iris E. Sommer, M.D., Ph.D., from the University Medical Center Groningen in the Netherlands, and colleagues used Finnish nationwide registers (61,889 individuals) to identify persons with schizophrenia/schizoaffective disorder and stratify by sex and
BioNTech's co-founders discuss their cancer vaccine We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info Data suggests the sixth wave of COVID-19 has peaked
In a recent study published in Science, researchers evaluated imprinted antibody responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages. Study: Imprinted antibody responses against SARS-CoV-2 Omicron sublineages. Image Credit: iunewind/Shutterstock Background SARS-CoV-2 Omicron sublineages represent an antigenic shift. They harbor unique spike (S) mutations that facilitate their escape from neutralizing antibodies (nAbs)
Sir David Jason says he had ‘seriously bad’ Covid We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info Covid cases have been surging once
In a recent study published in the Journal of the American Medical Association, researchers investigated the association between two or three doses of the messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccine and viral loads and symptoms during infections with different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. Study: Association of mRNA Vaccination
When 21-year-old Juliana Pascarella first noticed little red spots on her body, she put it down to a ‘harmless’ rash. But within 15 minutes she experienced bruises and swelling, a nose bleed that wouldn’t stop, and a scab appearing on her lip. Juliana, from Virginia, was taken to hospital and diagnosed with ITP – a
How muscular A-listers like Nicole Kidman and Gwyneth Paltrow are promoting a false body image as PROFESSOR JOYCE HARPER argues a six-pack after menopause is NOT normal…or healthy Taut, flat tummies. Perfectly toned buttocks. And not a bingo wing in sight. This is what the modern menopausal woman looks like, judging by the celebrity poster
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