In a trial of one of the main class of prescription sleeping pills, half the participants slept through a fire alarm as loud as someone vacuuming next to their bed. But a newer alternative preserves the ability to wake in response to danger signals, according to a new research. Published this week in Frontiers in
(HealthDay)—The incidence of phlebitis caused by peripheral intravenous cannula insertions may be higher among patients with certain risk factors, according to a study published online Dec. 27 in the Journal of Clinical Nursing. Dragana Simin, Ph.D., R.N., from the University of Novi Sad in Serbia, and colleagues evaluated complications among 368 adult patients undergoing 1,428
Monash University engineers have unlocked the door to earlier detection of cancer with a world-first study identifying a potential new testing method that could save millions of lives. Researchers found that a sensor using new, more sensitive materials to look for key markers of disease in the body increased detection by up to 10,000 times.
January 2, 2019—As early as 3 months of age, infants with a severe form of epilepsy called Dravet syndrome start having convulsive seizures, during which their arms and legs jerk repeatedly. As they become toddlers, another type of seizure begins to appear. These seizures do not cause obvious convulsions, but disrupt consciousness and can occur
(HealthDay)—College students face a much higher risk for the deadly bacterial infection meningitis B, a new analysis shows. Investigators from the U.S. Centers for Disease Control and Prevention found that students who were aged 18 to 24 were 3.5 times more likely to contract meningitis B than their peers who were not in school. The
A major Cardiovascular (CV) risk factor is low-density Lipoprotein Cholesterol (LDL-C). A lot of evidence that was accumulated supports a linear association between LDL-C levels and CV risk. However, whether the lower limit of LDL-C might offer CV benefits without any safety concerns is still a topic of debate. This review discusses data from studies
When we perceive the world around us, certain objects appear to be more noticeable than others, depending on what we do. For example, when we view a forest-covered mountain from a distance, the forest looks like a large green carpet. But as we get closer, we start noticing the individual trees, and the forest fades
(HealthDay)—Women with prior false-positive screening results have an increased risk for screen-detected and interval breast cancer for more than 10 years, according to a study published online Dec. 18 in the British Journal of Cancer. Marta Román, from the Hospital del Mar Medical Research Institute in Barcelona, Spain, and colleagues examined the long-term risk for
We know a good meal can stimulate the release of the feel-good hormone dopamine, and now a study in humans from the Max Planck Institute for Metabolism Research in Germany suggests that dopamine release in the brain occurs at two different times: at the time the food is first ingested and another once the food
Incorporating genetic diversity into a mouse model of Alzheimer’s disease resulted in greater overlap with the genetic, molecular and clinical features of this pervasive human disease, according to a study funded by the National Institute on Aging (NIA), part of the National Institutes of Health. The study also suggests that adding genetic diversity may be
Some of you may have made a New Year’s resolution to hit the gym to tackle that annoying belly fat. But have you ever wondered how physical activity produces this desired effect? A signaling molecule called interleukin-6 plays a critical role in this process, researchers report December 27 in the journal Cell Metabolism. As expected,
The neurological disorder Huntington’s disease causes behavioural and motor changes, which among other things are a result of dysfunctional maturation or formation of glial cells, the brain’s support cells, researchers from the University of Copenhagen demonstrate in a new study based on mouse trials. The researchers’ long-term goal is to be able to use the
A meta-analysis of randomized controlled trials found that catheter ablation was superior to conventional drug therapy alone for patients with atrial fibrillation and heart failure. Findings are published in Annals of Internal Medicine. Atrial fibrillation is associated with thromboembolic stroke, systemic embolism, and decompensated heart failure. Catheter ablation is an established therapeutic strategy for atrial
The relationship between socioeconomic status (SES) and brain anatomy is mostly stable from childhood to early adulthood, according to a longitudinal neuroimaging study of more than 600 healthy young people published in JNeurosci. This finding draws attention to the importance of preschool life as a period when associations between SES and brain organization may first
DUBLIN, Dec. 21, 2018 /PRNewswire/ — Jazz Pharmaceuticals plc (Nasdaq: JAZZ) today announced that the U.S. Food and Drug Administration (FDA) has extended the review period for its new drug application (NDA) for solriamfetol as a treatment to improve wakefulness and reduce excessive daytime sleepiness in adult patients with narcolepsy or obstructive sleep apnea (OSA).
(HealthDay)—The U.S. Food and Drug Administration is implementing a number of steps for long-term safety monitoring of the permanent birth control device Essure, which will no longer be sold or distributed in the United States after Dec. 31, 2018. Device maker Bayer announced in July that it would halt sales due to declining use of
An experimental drug known as A03, which was previously developed to treat depression, increases the levels of the enzyme Sirtuin1, or SirT1, and improves memory in mice. The mice were genetically modified to have a protein called ApoE4, the most common genetic risk factor for Alzheimer’s disease in humans that has been linked to some
Human error, not human biology, largely accounts for the apparent decline of mortality among the very old, according to a new report publishing on December 20 in the open-access journal PLOS Biology by Saul Newman of Australia National University in Canberra. The result casts doubt on the hypothesis that human longevity can be greatly extended
Scientists at the University of Glasgow have discovered a potential combination therapy for the treatment of chronic lymphocytic leukaemia (CLL), the most common form of leukaemia in the Western world, diagnosed in more than 3,500 people in the UK each year. The research, carried out in collaboration with NHS Greater Glasgow and Clyde (NHSGGC) and
A new study links higher levels of several key nutrients in the blood with more efficient brain connectivity and performance on cognitive tests in older adults. The study, reported in the journal NeuroImage, looked at 32 key nutrients in the Mediterranean diet, which previous research has shown is associated with better brain function in aging.