Category: Health Problems

FDA approves new standard of care for kidney cancer

The standard of care for kidney cancer patients continues to improve. The U.S. Food and Drug Administration granted approval to the combination of two immunotherapy drugs, ipilimumab and nivolumab, for the treatment of metastatic kidney cancer. The results of the large, international clinical trial leading to the approval were just published the prestigious New England

One class of drug used to treat type 2 diabetes may not reduce the risk of death when compared with placebo

One class of drug used to treat type 2 diabetes may not reduce the risk of death when compared with placebo, suggests new findings. The research, led by scientists from Imperial College London and published in the Journal of the American Medical Association, studied three types of diabetes treatment: sodium-glucose cotransporter 2 (SGLT-2) inhibitors, glucagon-like

An off-the-shelf, dual-targeted CAR T-cell product shows promising results in preclinical studies

FT819, an off-the-shelf, T-cell receptor (TCR)-less CD19 CAR T-cell product that could potentially be made more accessible to cancer patients than conventional CAR T-cell therapies showed positive results in preclinical specificity, functionality, and efficacy studies, according to data presented at the AACR Annual Meeting 2018, April 14-18. “Chimeric antigen receptor (CAR) T-cell therapy has shown

Scientists discover hidden structure of enigmatic ‘backwards’ neural connections

For decades, the neuroscience community has been baffled by the existence of dense connections in the brain that seem to be going “backwards.” These connections, which span extensively across distant areas of the neocortex, are clearly conveying important information. But until now, the organization of the connections, and therefore their possible role, was largely unknown.

Mood and personality disorders are often misconceived

With each new version of the widely-used manual of mental disorders, the number of mental health conditions increases. The latest version (DSM-5) lists around 300 disorders. To complicate things, many share common features, such as depression and anxiety. The manual is a useful guide for doctors and researchers, but making a diagnosis is not a

Tracking quality of life during prostate cancer treatment

Patients with advanced prostate cancer who received more intensive treatment experienced worse quality of life three months after treatment, but a better quality of life in the long term, compared to those on standard therapy, according to a new Northwestern Medicine study. The findings were published in the Journal of Clinical Oncology. “Treatment of prostate

Raw fruit and vegetables provide better mental health outcomes

Seeking the feel good factor? Go natural. That is the simple message from University of Otago researchers who have discovered raw fruit and vegetables may be better for your mental health than cooked, canned and processed fruit and vegetables. Dr. Tamlin Conner, Psychology Senior Lecturer and lead author, says public health campaigns have historically focused

What you need to know about fever in adults

(HealthDay)—When it comes to a fever, what’s true for kids isn’t necessarily so for adults. Even a slight temperature in a child warrants a call to the doctor. That’s not the case, though, for most fevers in most adults. What’s considered a normal temperature varies from one adult to the next. In general, though, 98.6

UN’s health body urges Hepatitis C offensive

Hepatitis C is easily cured. Yet, about 400,000 people die of the liver disease every year as only a smattering get the medicine they need. On Friday, the World Health Organization (WHO) urged governments to attack the problem with more urgency, and more money. Only about three million people from an estimated 71 million Hepatitis

Germany: compensated cirrhosis substantially increases comorbidities and healthcare costs

An analysis of outcomes and costs for German patients with non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH) who develop compensated cirrhosis was presented today at The International Liver Congress 2018 in Paris, France. Healthcare costs for this population spiked in the first year after compensated cirrhosis diagnosis. Comorbidities were common and one in five patients

Cancer protein could point to new targets for treatment

A new view of a protein frequently mutated in pituitary tumors is overturning conventional wisdom and could point to novel targets for cancer drugs. The protein, a “G protein” called Gαs, initiates messages inside cells. But a single mutation alters Gαs action in a surprising way. The protein’s molecular “off switch” actually switches activity on,

Smart egg cartons to transport cells to cure diabetes

We have developed “smart egg carton” packages for transporting live human pancreas cells for transplantation to diabetic patients. The egg cartons provide oxygen and allow physical separation to prevent damage and death to the cells – known as islet cells – during transport. Besides a whole pancreas transplant (which has a high mortality rate), currently

FDA approves contact lenses that shade the sun

(HealthDay)—The lives of contact lens wearers just got a whole lot easier. On Tuesday, the U.S. Food and Drug Administration approved the first contact lenses that can act like sunglasses. A special additive automatically darkens the lenses when exposed to bright light, while they become clear again in normal or dark lighting conditions. “This contact