Drug duo approved for aggressive thyroid cancer

(HealthDay)—Two anti-cancer drugs administered together have been approved by the U.S. Food and Drug Administration to treat an inherited form of thyroid cancer. Tafinlar (dabrafenib) and Mekinist (trametinib) combined have been approved to treat anaplastic thyroid cancer caused by an abnormal BRAF V600E gene, the agency said Friday in a news release. Anaplastic thyroid cancer

How Not To Let Money Problems Affect Your Health

It is not uncommon for people to have a heart attack when the stock market crashes, taking all of their money with it, because people are very attached to money. After all, we all need money to survive these days, that is why financial stress is a big part of our lives. However, studies have

Fifteen percent of osteoporosis patients who take ‘drug holidays’ suffer bone fractures

Patients who take osteoporosis drugs for long periods typically are advised to temporarily discontinue the drugs to prevent rare but serious side effects to the jaw and thighs. A Loyola Medicine study has found that 15.4 percent of patients who take so-called “drug holidays” from osteoporosis drugs called bisphosphonates experienced bone fractures. During a six-year

Punctal plug deemed beneficial in ocular surface disease

(HealthDay)—For patients with ocular surface disease (OSD) using prostaglandin analogue monotherapy, a punctal plug improves OSD and reduces intraocular pressure (IOP), according to a study published online April 26 in Clinical & Experimental Ophthalmology. Justin C. Sherwin, M.B., B.S., from the University of Oxford in the United Kingdom, and colleagues conducted a randomized controlled trial

Revealed: The 7 things that could be ruining your sleep

Revealed: The 7 things that could be ruining your sleep – from bedroom design to eating patterns Poor sleep impacts on mood and concentration, and the effects have been linked to serious health issues But as we increasingly burn the candle at both ends, many of us struggle to doze off when we do want

New breast cancer targets

Genome-wide association studies (GWAS) have identified more than 150 genetic variations associated with increased risk for breast cancer. Most of these variants are not located in protein-coding gene regions but are assumed to regulate the expression of certain genes. One way to figure out what these variants are doing is to conduct a cis-eQTL analysis.

Urine of kidney disease patients contains diverse mix of bacteria

The urine of kidney disease patients contains a diverse mix of bacteria such as Staphylococcus and Streptococcus, according to a study by researchers at Loyola Medicine and Loyola University Chicago. The bacteria diversity generally was higher among kidney patients who also experienced urinary urgency (sudden, urgent need to urinate). The study findings could lead to

Could THIS stop you from ever getting fat?

A tale of two mice: Both have been fed a diet of burgers and pizza but the one on the right is still SLIM and scientists say the secret could stop you from getting fat! Danish researchers claimed it was ‘impossible’ for the rodents to put on weight  Copenhagen University scientists deleted an enzyme in

Prescribing guidelines not always followed for patients on cholesterol-lowering drug

New Zealand prescribers do not always follow guidelines when prescribing other medicines to patients taking simvastatin, according to University of Otago researchers from the Pharmacoepidemiology Research Network. Simvastatin is a cholesterol-lowering drug that is widely used in New Zealand to prevent major cardiovascular events such as heart attacks and stroke. However, some medicines can inhibit

Home gym: the benefits of a cross-country ski machine

(HealthDay)—When it comes to both fun and efficiency, cross-country skiing is an exhilarating, high-calorie burner. It’s a lot less expensive than downhill skiing—all you need are the skis and a flat, snowy trail. But you can get the same benefits any time of year with a home Nordic or cross-country ski machine when you work

The DES saga: Death risk high for young women exposed in utero

A letter from three University of Chicago researchers in this week’s New England Journal of Medicine updates a 47-year-old series of reports on the risks of exposure during pregnancy to a supplement, diethylstilbestrol (DES), that was once widely used but since 1971 has been linked to a rare cancer: clear-cell adenocarcinoma of the vagina and

Reproductive markers associated with risk of diabetes

(HealthDay)—Markers of reproductive history, including age of menarche and parity, may be tied to future diabetes risk in women with a body mass index (BMI) ≥25 kg/m², according to a study published in Diabetes, Obesity and Metabolism. Nirmala Pandeya, Ph.D., from the University of Queensland in Brisbane, Australia, and colleagues used data from 126,721 middle-aged