Teams at the Institut Pasteur, CNRS, Vaccine Research Institute (VRI) and Université de Paris have discovered a new function of anti-HIV-1 antibodies by applying cutting-edge microscopy techniques to in vitro viral cultures. The scientists found that certain antibodies already known for effectively targeting HIV-1 envelope (Env) protein can prevent infected cells from releasing viral particles,
For children suffering from rare diseases, it usually takes years to receive a diagnosis. This “diagnostic odyssey” is filled with multiple referrals and a barrage of tests, seeking to uncover the root cause behind mysterious and debilitating symptoms. A new speed record in DNA sequencing may soon help families more quickly find answers to difficult
Neurologic complications from COVID-19 are common and can range from decreased mental clarity to stroke. A recent perspective article outlines what we know about these complications so far. The authors explain how prior assumptions that the virus directly affected brain cells have been disproven. Instead, nervous system injury is likely a result of severe inflammation
Investigators from UCLA Jonsson Comprehensive Cancer Center have identified a germline biomarker signature that successfully predicts which patients will suffer serious side effects that occur in up to 3 in ten patients on anti-PD1/PDL1 therapy, a promising new approach to treating cancer. Checkpoint inhibitors that enhance the immune system against PD-1 and PD-L1 show great
Findings from the UK’s world-leading human challenge study provide new insights into mild infections with SARS-CoV-2 in healthy young adults. The collaborative study is the first in the world to perform detailed monitoring over the full course of COVID-19, from the moment a person first encounters SARS-CoV-2, throughout the infection to the point at which
A graft can be a life-saving device for coronary heart disease, which remains the leading cause of death for both men and women in the United States. However, at small diameters -; such as the coronary artery in the heart -; long-term graft failure rates are often higher than 40 percent. A major cause of
Women hail plans to offer HRT at chemists as over-the-counter pills could be launched in months Consultation launched on allowing chemists to sell HRT treatment over counter HRT could be made available before end of year, but only Vagifem drug initially The suppository tablets treat vaginal dryness caused by estrogen deficiency Women have welcomed plans
Ketamine could help save the lives of suicidal people: Patients given illegal party drug were TWICE as likely to be rid of their dark thoughts within three days Ketamine is short-term effective treatment for some suicidal patients in hospital Two-thirds of patients given drug don’t have suicidal thoughts three days later Researchers say some patients
If you purchase an independently reviewed product or service through a link on our website, SheKnows may receive an affiliate commission. If your child watches Encanto on repeat (and yes, we’re all guilty of that), you’ll love this: Little Golden Books has published an edition based on the popular Disney film and it’s selling on
In one of the first studies to examine the link between neighborhood characteristics and weight gain during pregnancy, Columbia University Mailman School of Public Health researchers find that pregnant people who live in walkable neighborhoods in New York City have lower odds of excessive gestational weight gain (GWG) than those who live elsewhere in the
Liver cancer: Expert discusses symptoms and treatments We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info Those seeking to lower their cancer risk are
Researchers at the Laureate Institute for Brain Research (LIBR) in Tulsa, Oklahoma, have identified an abnormal link between the autonomic and central nervous systems, specifically via communication between the heart and part of the brain’s frontal cortex, in women with generalized anxiety disorder (GAD). The team’s objective was to test whether individuals suffering from GAD
Dr David Lloyd discusses using diabetes drug for anti-aging We use your sign-up to provide content in ways you’ve consented to and to improve our understanding of you. This may include adverts from us and 3rd parties based on our understanding. You can unsubscribe at any time. More info Diabetes affects nearly five million people
A large multinational group of researchers has shown how the Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has gained exceptional immune evasion properties but also a much lower propensity to enter cells such as those in lung alveoli, resulting in its reduced pathogenicity. Their paper is currently released as an unedited
Want to dodge bone, muscle or joint pain in your 60s? Only vigorous exercise such as running, tennis and swimming will spare you, study claims Vigorous exercise needed at least once a week ito ward off musculoskeletal pain Researchers say walking and household chores is not sufficient to reduce risk Nearly two-thirds of over-75s in
(HealthDay)—For patients with noncholecystitis (NC) gallbladder disease who are poor surgical candidates, endoscopic ultrasound‑guided transluminal gallbladder drainage (EUS-GBD) appears to be safe and effective for managing gallstone disease, according to a study recently published in Endoscopic Ultrasound. Duncan J. Flynn, M.D., from Massachusetts General Hospital in Boston, and colleagues examined outcomes for EUS-GBD using data
Tonga will go into COVID-19 lockdown Wednesday after the virus was detected in a fresh blow to the Pacific kingdom as it struggles to recover from last month’s devastating volcanic eruption, officials said. The remote island nation had been virus free, but Prime Minister, Siaosi Sovaleni said two men tested positive this week in Nuku’alofa.
A recently released study in the journal Statistics in Medicine describes a new method, named the Observers Needed for Evaluation of Subjective Tests (ONEST), developed to determine the optimal number of pathologists needed for a correct diagnosis. The method was developed by Gang Han, Ph.D., associate professor in the Department of Epidemiology and Biostatistics at the Texas A&M University School of
(HealthDay)—A polygenic score derived from pharmacogenomic evaluation of cytarabine (ara-C) pathway can help personalize treatment for pediatric patients with acute myeloid leukemia (AML), according to a study published online Jan. 18 in the Journal of Clinical Oncology. Abdelrahman H. Elsayed, Ph.D., from the University of Florida in Gainesville, and colleagues analyzed single nucleotide polymorphisms (SNPs)
Breakdowns in regulatory mechanisms cause iron to build up in the brain as organisms grow older, increasing oxidative stress and causing cellular damage, according to a Northwestern Medicine study published in the journal eLife. This mechanism may explain some age-related cognitive decline and contribute to neurodegenerative diseases such as Parkinson’s and Alzheimer’s disease, according to
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