With antibiotic resistance, ‘we are running out of options’

Experts predict that without intervention, the problem of multidrug-resistant bacterial infections could be catastrophic by 2050, killing nearly 10 million people each year. To seek solutions, the National Institutes of Health awarded a five-year, $1.8 million grant to Joseph Boll, assistant professor of biology at The University of Texas at Arlington, to identify and inhibit

Four ways to stop COVID ruining Christmas again in 2021

This autumn the UK has had between 30,000 and 50,000 new COVID cases each day, and globally cases are rising again after months of steady decline—so much so that many countries are reintroducing measures to curb the virus. Austria is back in lockdown, with other European countries considering similar measures. So like last year, this

Biomedical engineers find neural activity during rest is highly organized

When mice rest, individual neurons fire in seconds-long, coordinated cascades, triggering activity across the brain, according to research from Penn State and the National Institutes of Health. Previously, this was thought to be a relatively random process—single neurons firing spontaneously at random times without external stimulations. The finding, published Nov. 18 in the Proceedings of

COVID-19 fallout may lead to more cancer deaths

Significant decreases in CT imaging for cancer persisted even after the peak of the COVID-19 pandemic in 2020, delaying diagnosis and treatment and raising the possibility of more advanced cancers and poorer outcomes for patients in the future, according to a study being presented next week at the annual meeting of the Radiological Society of

Spread and evolution of SARS-CoV-2 lineages with possible recombination events

Virus recombination is a typical aspect of sarbecovirus evolution, in which genetic material from two genetically diverse parental lineages isis merged into a viable descendent virus genome. During the evolutionary history of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), genomic investigations reveal recombination events among coronaviruses circulating in non-human species occurred. During the coronavirus disease

Premenopausal Oophorectomy Linked to Later Cognitive Impairment

Women whose ovaries were surgically removed before the age of 46 had a higher risk of mild cognitive impairment (MCI) around 30 years later, compared with those who did not undergo bilateral oophorectomy, according to a population-based linkage study published in JAMA Network Open. The findings suggest that “physicians treating women with premenopausal bilateral oophorectomy

Simplifying PCR set-up with INTEGRA’s range of pipettes

INTEGRA Biosciences’ selection of liquid handling tools provides scientists worldwide with the solutions they need for their PCR workflows. The company offers an array of options for manual, electronic or fully automated pipetting, and volumes ranging between 0.2 µl and 5000 µl. Combined with INTEGRA’s unique GripTip system, which ensures pipette tips never leak or

Using short-acting opioids in the hospital could improve care for patients experiencing opioid withdrawal without pain

Expanding the use of short-acting opioids in situations where pain is not present, but where methadone or buprenorphine provide inadequate relief, may benefit hospitalized patients suffering from opioid withdrawal symptoms. While current U.S. guidelines do not recommend short-acting opioids for these patients, an expert commentary from the University of Toronto and Harvard Medical School suggests

How T cells recognize infection or disease

Monash University researchers have expanded their knowledge of how T cells might recognize infections or disease, providing key insight into how an often-overlooked T cell lineage becomes activated when encountering pathogens such as viruses, bacteria, and cancers. T cells communicate with other cells in the body in search of infections or diseases. This crosstalk relies

A Vaccine by Any Other Name: Behind COVID Vax Brand Names

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. What to know: Most of the currently developed vaccines for COVID-19 have brand names, but the general public, the media, and medical professionals still mostly use the pharmaceutical companies’ names, like “the Pfizer vaccine” or “the Moderna vaccine.“ This is partly

A Vaccine by Any Other Name: Behind COVID Vax Brand Names

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. What to know: Most of the currently developed vaccines for COVID-19 have brand names, but the general public, the media, and medical professionals still mostly use the pharmaceutical companies’ names, like “the Pfizer vaccine” or “the Moderna vaccine.“ This is partly

Ancient natural medicine could improve cancer treatment

For centuries, people all over the world have been using medical plants to fight infections, boost wound healing, and for religious ceremonies. And for centuries, scientists have been trying to identify the active substances in these plants in order to use them in modern-day medicine. Now researchers from the University of Copenhagen have studied an