Diagnosing kidney disease: Removing race from the equation

Scientists generally estimate the glomerular filtration rate (GFR) — a measure of kidney function — by assessing the levels of creatinine or cystatin C in the body. Current equations for estimated GFR (eGFR) that use creatinine or cystatin C incorporate age, sex, and race to get this measurement. However, the inclusion of race in these

Blood plasma protein fibrinogen interacts directly with nerve cells to cause brain inflammation

Neuroinflammatory diseases, including Alzheimer’s disease and traumatic brain injury, have been linked to deposits of a tough protein known as fibrin, derived from the blood clotting factor fibrinogen. These mesh-like fibrin deposits occur outside blood vessels in the brain, contributing to the death of certain central nervous system cells (neurons) that eventually leads to impaired

SURTAVI at 5 Years Reinforces TAVR but Was It Long-term Enough?

The SURTAVI trial has become the second major face-off between transcatheter and surgical aortic valve replacement (TAVR and SAVR, respectively), after PARTNER 2A, to show parity in 5-year clinical outcomes in patients with severe, symptomatic aortic stenosis at intermediate surgical risk. The new SURTAVI results, like those from the other trial that used different TAVR valves,

French schoolchildren mask up again as COVID cases rise

Schoolchildren in large parts of France were ordered Monday to again wear face masks in class, less than a month after being allowed to remove them, as the country tries to tamp down a surge in COVID cases. Primary schools in 40 of France’s 101 departments or administrative areas, which had been mask-free for weeks,

Experts worry plateau in US COVID cases foretells winter spike

A plateau in U.S. COVID-19 cases following several weeks of declining infections is a “worrisome” indication for a potential spike this winter as people congregate inside more often because of holidays and colder weather, a Johns Hopkins University expert said Friday. The United States had been reporting case declines of 10 percent or more each

Slovaks expand restrictions, plan more amid record surge

Slovakia on Monday expanded strict coronavirus restrictions including hotel, bar and restaurant closures to almost a half of the country amid a record surge of infections. The government is expected to discuss additional measures as the country’s health minister joined medical personnel who treat COVID-19 patients in urging Slovaks to get vaccinated. “Only vaccination can

Nationwide polio eradication campaign starts in Afghanistan

The Taliban-run Afghan public health ministry announced Sunday the start of a four-day nationwide polio vaccination campaign aimed at inoculating children under age 5. For the past three years before taking control of Afghanistan, the Taliban had barred U.N.-organized vaccination teams from doing door-to-door campaigns in parts of the country under their control. The group