Societies Issue Joint Statement on Safe Use of HCQ

Hydroxychloroquine can be used safely and effectively with attention to dosing, risk factors, and screening, but communication among physicians, patients, and eye care specialists is key to optimizing outcomes and preventing complications, according to a joint statement from four medical societies. The American College of Rheumatology, American Academy of Dermatology, Rheumatologic Dermatology Society, and the

New ASH Guidelines: VTE Prevention, Treatment in Cancer Patients

New guidelines from the American Society of Hematology “strongly recommend” using no thromboprophylaxis over using parenteral thromboprophylaxis in ambulatory patients receiving cancer chemotherapy who have low venous thromboembolism (VTE) risk, and using no thromboprophylaxis over oral thromboprophylaxis with vitamin K antagonists in those at any VTE risk level. The evidence-based guidelines for the prevention and

Fast-tracking drug development for neurodegenerative disorders

A Griffith University-led research team has discovered how a therapeutic target common among debilitating neurodegenerative disorders is activated, which could help accelerate drug development. In a study published in the journal Neuron, the researchers from Griffith University’s Institute for Glycomics, the University of Queensland and Washington University, analyzed the structure and function of a protein

Real Ways To Support Your Partner When They’re Depressed

When you’re in a relationship with someone who’s depressed, watching them struggle can also hit you hard. You’re 100 percent committed to being there for your partner and showing them that you care, but you’re unsure about how to support them in a way that is actually helpful and also respects their boundaries. It doesn’t

Comet supercomputer reveals the mechanical process of cancer growth

According to the World Health Organization, one in six worldwide deaths have been attributed to cancer; however, these fatalities were not due to initial malignant tumors-;the deaths were caused by the spread of cancer cells to surrounding tissues and subsequent tumor growth. These tissues, which consist largely of collagen, have been the focus of a

When should patients with dementia receive palliative care?

Patients with dementia may benefit from being referred to specialist palliative care—a branch of medicine that focuses on optimizing quality of life and providing relief from symptoms—but who should be referred, and when? A recent analysis of published studies on the topic found a lack of consensus regarding referral criteria for palliative care in patients

Study links kidney stones with bone problems

In an analysis of nationwide data from the Veterans Health Administration, approximately one-quarter of individuals with kidney stones had a diagnosis of osteoporosis or bone fracture around the time of their kidney stone diagnosis. The findings are published in the Journal of Bone and Mineral Research. Investigators identified 531,431 patients with kidney stone disease between

Eat These 5 Foods to Support Your Immune System

Vitamins and supplements are highly useful tools for a lot of folks looking for some immune system support through cold and flu season and beyond. But they are just that—tools. They are not a foolproof solution to stay healthy. The best way to achieve that goal, and support a strong immune system, is by packing

Nanoparticle-delivered COVID-19 vaccine candidate shows promise in preclinical studies

Researchers from Cleveland Clinic’s Global Center for Pathogen Research & Human Health have developed a promising new COVID-19 vaccine candidate that utilizes nanotechnology and has shown strong efficacy in preclinical disease models. According to new findings published in mBio, the vaccine produced potent neutralizing antibodies among preclinical models and also prevented infection and disease symptoms

Willpower is the key to enhancing learning and memory: Researchers uncover the mechanism

Active or voluntary learning is a major topic in education, psychology, and neuroscience. Over the years, numerous studies have shown that when learning occurs through voluntary action, there is a modulation of attention, motivation and cognitive control that makes the process much more effective. Consequently, memory is benefited. However, although the physiological processes underlying this

Researchers find effective combination of therapies for managing mitochondrial disease

Researchers from the Mitochondrial Medicine Frontier Program at Children’s Hospital of Philadelphia (CHOP) have demonstrated how one combination of therapies may be beneficial for patients with mitochondrial respiratory chain disorders. This preclinical research paves the way to develop more tailored treatment options for patients with inherited mitochondrial disease and acquired energy disorders. The findings emphasize

Ethnic minorities have less access to COVID-19 vaccines, finds study

With several vaccines already having received Emergency Use Authorization (EUA) against coronavirus disease 2019 (COVID-19), vaccination campaigns have already begun in several countries the world over. However, as with the disease itself, the remedy continues to be plagued by issues of inequity and disparity. A new preprint examines the racial and ethnic differences between COVID-19