What is Calcium?

In humans, calcium is the most abundant mineral and forms about 2% of our total body weight. Almost all of this calcium is found in the skeleton and the rest is found in the teeth, the blood plasma, the body’s soft tissues and the extracellular fluid. The main role of calcium in the body is

Insulin Resistance Pathophysiology

Glucose is one of the body's most important sources of energy. Glucose is absorbed from the blood into cells where it provides energy for a range of cellular functions. This cellular uptake of glucose is facilitated by the hormone insulin, which is secreted by the beta cells of the pancreas. Insulin also helps convert excess

Docetaxel (Taxotere) and Gastric Cancer

Docetaxel is a chemotherapy drug that is used to treat several forms of cancer. On March 22nd 2006, the United States Food and Drug Administration (FDA) approved the use of docetaxel in combination with cisplatin and flourouracil for the treatment of patients with advanced gastric adenocarcinoma who had not yet received chemotherapy for advanced disease.

Dopamine Functions

Dopamine is a neurotransmitter released by the brain that plays a number of roles in humans and other animals. Some of its notable functions are in: movement memory pleasurable reward behavior and cognition attention inhibition of prolactin production sleep mood learning Dopamine. Image Credit: Meletios / Shutterstock Excess and deficiency of this vital chemical is

What are Hepatocellular Carcinomas?

Hepatocellular carcinoma is the most common type of malignant liver cancer. Primary liver cancers are rare and the condition usually occurs as secondary to viral hepatitis or cirrhosis. Patient prognosis depends on the size, stage and grade of the tumor at diagnosis. The symptoms of this condition are usually non-distinct and only occur once the

What are Amyloid Plaques?

Amyloid plaques are aggregates of misfolded proteins that form in the spaces between nerve cells. These abnormally configured proteins are thought to play a central role in Alzheimer's disease. The amyloid plaques first develop in the areas of the brain concerned with memory and other cognitive functions. The amyloid hypothesis Amyloid plaques form when pieces

What is Testosterone?

Testosterone is the principle sex hormone responsible for the development of reproductive function in male vertebrates. Testosterone is one of the hormones referred to as androgens, which are also known of as anabolic steroids. As a steroid hormone, testosterone is derived from cholesterol and the structure of this hormone is similar across all mammals, reptiles,

What is Cystitis?

The term cystitis refers to inflammation of the bladder and is usually caused by infection. The risk of bladder infection is increased by factors such as urinary tract infection, injury or irritation of the urethra, transfer of bacteria from the anus to the urethra and difficulty fully emptying the bladder due to pregnancy or prostate

What is the Alpha Fetoprotein Test?

Many imaging and serologic tests have been evolved to help predict the occurrence of congenital disease. One such test is the maternal serum alpha-fetoprotein screening test (MS-AFP). Image Credit: Jarun Ontakrai/Shutterstock.com Indications The MS-AFP test is a routinely offered screening test for all antenatal women because it is both efficient and cost-effective as a method

Cesarean Section Anaesthesia

A cesarean section or C-section is an abdominal surgery that is performed to deliver a baby via an incision made in the abdomen and womb. Sometimes this is the safest option in cases where a normal vaginal birth may pose a risk to the mother or baby. Some examples of when a C-section may be

Double Inlet Left Ventricle (DILV)

Double inlet left ventricle (DILV) is a congenital heart condition in which the heart chambers and valves are defective. As a result, the heart ventricles are replaced by a single pumping chamber. This is therefore one of the single or common ventricle defects. The Normal Heart Structure Normally, the heart has four chambers, and two

Introduction to the Coulter Principle

The Coulter Principle is the reference method for studying particle size and dynamics, which is based on measurable variations in electrical impedance that is produced by non-conductive particles in an electrolyte solution. Today it is also used as limit test for particulate matter in parenteral solutions of large volumes. Since Coulter patented a method to

Voiding Cystourethrogram

A voiding cystourethrogram (VCUG) is a fluoroscopic examination of the bladder and urethra while the patient is micturating. It is most often used in the pediatric population to confirm or rule out the diagnosis of vesicoureteral reflux (VUR). This is a medical condition in which urine flows in a retrograde fashion from the bladder to

Down Syndrome Symptoms

Down syndrome or Down's syndrome is a congenital condition that typically gives rise to characteristic physical features and a level of learning disability, which while common amongst those with Down’s, will vary between individuals in terms of appearance and severity. Down’s syndrome is one of the most common chromosomal disorders, with approximately 6,000 babies per

Proteomics Uses

The term proteome, coined in 1995, refers to the protein composition of the genome, while the term proteomics represents a systematic analysis of those proteins. Proteomics is used to detect protein expression patterns at a given time in response to a specific stimulus, but also to determine functional protein networks that exist at the level

Medical Tourism History

The practice of travelling for health and medical reasons has a long history. Even the ancient civilizations recognized the therapeutic effects of mineral thermal springs and sacred temple baths. For example, the Sumerians constructed health complexes around hot springs more than four thousand years ago, which included temples with flowing pools. Ancient Romans built resorts

Characterizing Nanoparticles

Nanoparticles are 1 – 100 nm in size and can consist of  one or a mixture of elements. Nanoparticles are commonly made up of inorganic substances such as gold, silver, or iron oxide, but can also comprise of liposomes and organic structures such as carbon nanotubes. Image Credit: Kateryna Kon / Shutterstock Nanoparticles can be

What is Repetitive strain injury (RSI)?

Repetitive strain injury (RSI) is a common disorder of the upper limbs that occurs mainly due to bad posture at work. There is commonly pain in the nerves, tendons and muscles that occurs due to overuse or repetitive movement. Repetitive strain injury is also known as Cumulative Trauma Disorder (CTD). Causes of RSI RSI is

What is Dandruff?

Dandruff is a skin condition that causes flakes of dead skin from the scalp to appear in the hair. A typical feature of this condition is a sensation of itchiness in areas of the scalp. The condition is not an infection and cannot spread from one person to another. Although dandruff does not cause any