Tag: Alzheimer’s

An experimental drug known as A03, which was previously developed to treat depression, increases the levels of the enzyme Sirtuin1, or SirT1, and improves memory in mice. The mice were genetically modified to have a protein called ApoE4, the most common genetic risk factor for Alzheimer’s disease in humans that has been linked to some

Despite the investment of hundreds of millions of dollars over the past several decades on the part of pharmaceutical companies, we still don’t have any meaningful treatment for Alzheimer’s disease. In fact, in a recent extensive study just published in the Journal of the American Medical Association, the two most commonly prescribed medications for Alzheimer’s

A ‘brain training’ app developed at the University of Cambridge could help people who suffer from obsessive compulsive disorder (OCD) manage their symptoms, which may typically include excessive handwashing and contamination fears. In a study published in the journal Scientific Reports, Baland Jalal and Professor Barbara Sahakian from the Department of Psychiatry, show how just

(HealthDay)—There’s growing evidence that the herpes virus responsible for cold sores also may cause Alzheimer’s disease, a new research paper contends. It’s been long known that herpes simplex virus 1 (HSV1) can been found in the brains of elderly people with Alzheimer’s disease, and research has shown that herpes increases Alzheimer’s risk in people genetically

WEDNESDAY, Oct. 17, 2018 — A precision map of a part of the brain of the lowly mouse could be a potent new research tool against Alzheimer’s, researchers say. The highly detailed look at the mouse hippocampus should provide new insight into a range of brain diseases in humans, according to the research team from

In a breakthrough human study, anti-oxidant, glutathione (GSH), which protects the brain from stress, has been found to be significantly depleted in Alzheimer’s patients compared to normal subjects. As GSH is a very important anti-oxidant that protects the brain from free radicals, the findings give us another measure to use when diagnosing potential for the

The National Institute on Aging (NIA) has awarded scientists at University of California San Diego School of Medicine and San Diego State University (SDSU) with a five-year, $4 million grant to boost the number of Latino and other underrepresented minority researchers studying Alzheimer’s disease (AD) and related dementias afflicting seniors of Latino origins, a demographic

About 5.7 million individuals in the United States are living with Alzheimer’s disease, according to the Alzheimer’s Association. This neurodegenerative disease is one of the leading causes of disability and the sixth-leading cause of mortality in the U.S. With annual healthcare costs of more than $250 billion, the disease also puts a significant strain on

Alzheimer’s myths busted: Experts reveal the six most common misconceptions patients have – which cause many to DELAY getting checked People worry they will have to stop driving, give up work, and lose their memory Approximately 50 million people around the world are living with dementia Alzheimer’s disease is the most common cause of the

Zombie cells are the ones that can’t die but are equally unable to perform the functions of a normal cell. These zombie, or senescent, cells are implicated in a number of age-related diseases. And with a new letter in Nature, Mayo Clinic researchers have expanded that list. In a mouse model of brain disease, scientists

A new survey released today finds that most U.S. adults (54 percent) are worried that they may develop Alzheimer’s disease, and a majority believe it is likely a cure will be developed in their lifetime (55 percent). However, the survey, conducted online by Harris Poll among more than 1,000 U.S. adults, also revealed a disconnect

Researchers at King’s College London have discovered a vicious feedback loop underlying brain degeneration in Alzheimer’s disease which may explain why so many drug trials have failed. The study also identifies a clinically approved drug which breaks the vicious cycle and protects against memory-loss in animal models of Alzheimer’s. Overproduction of the protein beta-amyloid is

For the first time since 2009, Stefanie Putnam is able to prepare — and eat — meals for herself, put the vest on her service dog, Kaz, and drive herself to activities with her horse without losing consciousness or gasping for breath. “My whole life has opened up for me again!” Putnam said. A C4

The amoeba Naegleria fowleri is commonly found in warm swimming pools, lakes and rivers. On rare occasions, the amoeba can infect a healthy person and cause severe primary amebic meningoencephalitis, a “brain-eating” disease that is almost always fatal. Other than trial-and-error with general antifungal medications, there are no treatments for the infection. Researchers at Skaggs

Researchers at the University of Florida have discovered that a modified version of an important immune cell protein could be used to treat Alzheimer’s disease. The study, which will be published August 29 in the Journal of Experimental Medicine, reveals that soluble versions of a protein called TLR5 can reduce the buildup of amyloid plaques

Testing how well people remember past events in their lives could help medical professionals make early predictions about who is at risk for developing Alzheimer’s disease, according to a new study from the University of Arizona. Researchers administered an “autobiographical memory” test to a group of 35 healthy adults, about half of whom carry the

Alzheimer’s disease is characterized by the formation of amyloid plaques in the brain, which interfere with the normal communication flow between brain cells. These plaques are made out of beta-amyloid amino acids that stick together. Over the past few years, researchers from various institutions have been working to develop antibodies — a type of protein

Two new studies published by investigators from Brigham and Women’s Hospital illustrate that not all forms of amyloid-beta (Aβ) protein — the protein thought to initiate Alzheimer’s disease — play an equally menacing role in the progress of the disease. Using a new way of preparing and extracting the protein as well as a new

An e-learning programme that trains care home staff to engage in meaningful social interaction with people who have dementia improves wellbeing and has sustained benefits. The average person with dementia in a care home experiences just two minutes of social interaction each day. They also showed that out of 170 available training programmes for nursing

Dementia is a large and growing concern. Because it cannot be reversed, understanding the best way to care for people with advanced dementia is increasingly important. Roughly 50 percent of people with dementia who are living in nursing homes experience substantial pain. According to earlier studies, this pain often goes unnoticed by clinicians and is