Tag: bone

Mesenchymal stem cells (MSCs) are thought to have great potential in the field of regenerative medicine, which has the aim of restoring damaged tissues. However, not much was known about in vivo plasticity of them—until now. Researchers have identified a subpopulation of MSCs that promote the healing of bone fractures and show an enhanced ability

Previously published solar exposure guidelines for optimal vitamin D synthesis based on a study of skin samples may need to be revised, according to new research published today in PNAS. A study by researchers from King's College London, with support from the NIHR Guy's and St Thomas' Biomedical Research Centre, has tested the optimum ultraviolet

People with rare disorders that cause shortened telomeres — protective caps that sit at the end of chromosomes — may be more likely to have blood cancers such as leukemia or myelodyplastic syndrome. Now, Johns Hopkins Medicine scientists have discovered several "self-correcting" genetic mutations in bone marrow that may protect such patients from these cancers.

Evidence continues to mount that vaccination against COVID-19, most notably the Pfizer and Moderna vaccines, produces robust, durable protection in the vast majority of recipients. But questions remain for some at greatest risk of a severe outcome from a COVID-19 infection: Recipients of donor organs and bone marrow whose immune systems are necessarily suppressed to

Shortage of hematologists or specialists to treat blood disorders in Africa requires urgent action, experts say. The acute shortage of hematologists in Sub-Saharan Africa has given rise to an urgent need for training to help address increasing cases of blood disorders, scientists say. The World Health Organization (WHO) recommends one clinical hematologist per 100,000 people

Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient's own blood-forming stem cells. The trial will combine CRISPR technology developed at Innovative Genomics

In an analysis of nationwide data from the Veterans Health Administration, approximately one-quarter of individuals with kidney stones had a diagnosis of osteoporosis or bone fracture around the time of their kidney stone diagnosis. The findings are published in the Journal of Bone and Mineral Research. Investigators identified 531,431 patients with kidney stone disease between

Researchers from Uppsala University show in a new study that inhibition of the protein EZH2 can reduce the growth of cancer cells in the blood cancer multiple myeloma. The reduction is caused by changes in the cancer cells' metabolism. These changes can be used as markers to discriminate whether a patient would respond to treatment

X-linked hypophosphatemia (XLH) is the most common cause of hereditary rickets in children. Its early recognition is crucial to appropriate pediatric management and surveillance for complications related to the disease as well as to its treatment. Diagnosis The clinical features of rickets is the bowing of the lower extremity bones following the initiation of weight

Bone infections caused by implants are difficult to treat and usually require a prolonged course of antibiotic treatment. In a new study, researchers from Kanazawa University discovered that implant-related bone infections can be effectively treated with a combinational treatment consisting of antibiotics and antibiotic-laden stem cells. Bone fractures often require implants for stabilization and effective

Low physical function and low muscle mass after hip fracture increased the risk for accelerated bone deterioration in older hip fracture patients. Acknowledgement of the risk factors is important for bone health and overall recovery. “Substantial decrements in physical function, muscle and bone strength occur after hip fracture, which markedly increase the risk for a

Several clinical trials have reported beneficial effects of organic nitrates on bone health, which could lead to a reduced risk of fractures. Some of these trials have been retracted because of scientific misconduct; however. A new study published in the Journal of Bone and Mineral Research found that organic nitrates do not have clinically relevant

Girl, nine, who beat bone cancer after doctors amputated and reattached her leg BACKWARDS now enjoys cycling, dancing and roller-skating Amelia Eldred, from Staffordshire, diagnosed with osteosarcoma in August 2017  Had a rotationplasty, in which doctors amputated her knee and part of her leg They then re-attached foot and heel joints back to front, to

Researchers from the UCLA School of Dentistry have provided insight into how the mechanical process of bone loss works and have also identified a protein that is responsible for recycling of the cells that can also promote bone loss. The team showed that by eliminating a key protein responsible for the activation of bone loss,

Why protein is especially in old age, is so important When people get older, this makes it more difficult to Remove. In the age Weight loss in addition to muscle and bone loss, a motor loss and an increased risk of falls. A new study from the US has now shown, however, that a calorie

Century long-overlooked network of blood vessels The organs of the human body are widely known – one would think. However, a German research team recently discovered a previously unknown System of fine blood vessels within our bones, that connects the bone marrow with the bone skin. Researchers from the University of Duisburg-Essen (UDE), of the

Drinking trendy bone broth like Gwyneth Paltrow could ‘lower blood pressure, prevent heart disease and protect against type 2 diabetes’ Cooking pig bones releases proteins that block enzymes linked to hypertension Also degrades hormones that drive high blood pressure and diabetes’ onset Researchers recommend people drink bone broth ‘habitually’  e-mail 72 View comments Drinking bone

Scientists have revealed the intricate process that bone cells use to repair themselves after mechanical injury, according to a study in the open-access journal eLife. The research provides new insight on how the body adapts to all kinds of mechanical stresses—from pressure placed on bones during simple walking, to extreme forces experienced during intense exercise.

Certain medications commonly used to treat heartburn, acid reflux, and ulcers are linked with higher bone fracture risks among patients on dialysis, according to a new study. Almost three-quarters of patients who had a hip fracture had used the medications in the 3 years preceding their event. The findings appear in an upcoming issue of

In this article, learn about the uses of a bone graft, the different types, and the possible risks. What is a bone graft? A person may need a bone graft if their body is unable to produce enough new bone in certain situations. Bone grafts can help in the treatment of: fractures, especially if they