Tag: Brain Injury

Sensory neurons can be used to discover therapies for ALS: New approach for testing for ALS may be useful to reverse debilitating disease

Virginia Tech Carilion Research Institute scientists have shown that mutations in specific genes that destroy motor neurons and thereby cause the devastating effects of amyotrophic lateral sclerosis — also known as ALS or Lou Gehrig’s disease — also attack sensory neurons. The discovery in today’s (Thursday, Nov. 8) Scientific Reports indicates that studying sensory neurons

Scientists opening up access to science through DIY equipment

Scientists at the University of Sussex have developed a piece of hardware to demonstrate how our brains function, as part of a growing range of equipment which uses DIY and 3D printable models to open up access to science education. Professor of Neuroscience, Tom Baden, has been working with colleagues to build Spikeling; a piece

Nature of immune cells in the human brain disclosed

Researchers from the Netherlands Institute for Neuroscience and Amsterdam UMC have disclosed the nature of how T cells protect the brain against harmful viruses. The results of the study, which are published in Nature Communications, are important for investigating the role of the immune system in numerous brain disorders. Immune system The immune system protects

Zombie cells found in brains of mice prior to cognitive loss

Zombie cells are the ones that can’t die but are equally unable to perform the functions of a normal cell. These zombie, or senescent, cells are implicated in a number of age-related diseases. And with a new letter in Nature, Mayo Clinic researchers have expanded that list. In a mouse model of brain disease, scientists

Sugar pills relieve pain for chronic pain patients: Placebo benefits can be predicted by brain anatomy and psychological traits

Someday doctors may prescribe sugar pills for certain chronic pain patients based on their brain anatomy and psychology. And the pills will reduce their pain as effectively as any powerful drug on the market, according to new research. Northwestern Medicine scientists have shown they can reliably predict which chronic pain patients will respond to a

Soccer heading may be riskier for female players

Researchers have found that women who play soccer may be more at risk than their male counterparts. According to a new study published in the journal Radiology, female soccer players exhibit more extensive changes to brain tissue after repetitive ‘heading’ of the soccer ball. Soccer is the most popular competitive sport in the world, and

Dr. Jekyll, Mr. Hyde: Healing mesenchymal cells morph and destroy muscles in models of spinal cord injury, ALS and spinal muscular atrophy: Targeting IL-6-STAT3 signaling in fibro-adipogenic progenitor (FAP) cells

When a muscle is acutely injured — whether through accidental strain or intentional weight lifting — special repair cells called fibro-adipogenic progenitors (FAPs) rush to the rescue. These cells coordinate the activity of the immune system and muscle stem cells to replace and repair the torn tissue. Now, scientists at Sanford Burnham Prebys Medical Discovery

Electricity sparks neuronal diversity during brain development: Bioelectrical potential is driving force for stem cells to generate different types of neurons during embryogenesis

The cerebral cortex is a highly developed brain region, which allows intellectual functions such as conscious perception, anticipation of events and language. These functions are mediated by specific sets of neuronal circuits. To understand how these circuits emerge during development, researchers from the University of Geneva (UNIGE), Switzerland, in collaboration with an American team, investigated

Researchers solve mystery of how ALL enters the central nervous system: Rather than breach the blood-brain barrier, the leukemia cells use a unique pathway

A deadly feature of acute lymphoblastic leukemia (ALL) is its invasion of the central nervous system. ALL in the central nervous system is very difficult to treat, because most drugs are blocked from the organ system due to a “blood-brain barrier” designed to protect the brain. How cancer cells enter the central nervous system has

Brain arousal compound noradrenaline plays critical role in sensory perception: Discovery paves way for detecting situations of dangerous lapses and for improving anesthesia protocols

Being aware of our surroundings is a fundamental aspect of our existence. But what in our biological makeup determines how we access and interpret the endless stream of information around us? A new Tel Aviv University study published in Current Biology suggests that noradrenaline, a neurotransmitter responsible for arousal in the brain, plays a vital

Increased brain injury markers in response to asymptomatic high-accelerated head impacts

Researchers from the University of Michigan found that serum levels of two biomarkers of traumatic brain injury, tau and ubiquitin C-terminal hydrolase L1, are elevated following high-acceleration head impacts, even when there is no clinical diagnosis of concussion. Their complete findings are reported today in the Journal of Neurosurgery, in the article “Elevated markers of

Nicotine alters neurotransmission in habit-forming brain region: Nicotine reduces dorsal striatal output, which may underlie urge to smoke and make it difficult to break the habit

A study of rat brain slices published in JNeurosci demonstrates how nicotine interacts with cells that regulate the output of a brain region involved in habit formation. The research could inform efforts to help people quit smoking and avoid relapse. The addictive qualities of nicotine have been attributed to the brain’s reward system. However, recent