Tag: Cancer

NHS knew ‘for a MONTH’ about cervical cancer screening blunder

NHS knew ‘for a MONTH’ about cervical cancer screening blunder that saw almost 50,000 women miss out on smear test invites and results More than 4,500 women were not sent the results of their screening tests  Whereas more than 40,000 were not sent appointment invitations or reminders  The BMA has called the situation ‘incredibly serious’

Defective DNA damage repair leads to chaos in the genome

Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now found a cause for the frequent catastrophic events in the genetic material of cancer cells that have only been known for a few years: If an important DNA repair system of the cells has failed, this promotes fragmentation and defective assembly of the

Cellphone Radiation Tied to Upped Odds for Cancer — in Rats

THURSDAY, Nov. 1, 2018 — Rats developed cancer after being exposed to high levels of cellphone radiation, but those levels were much higher than what people are exposed to when using their cellphones, a new government report says. When exposed to radio frequency radiation like that used in 2G and 3G cellphones, male rats developed

Loss of protein p53 helps cancer cells multiply in ‘unfavourable’ conditions: The loss of tumor protein p53 ensures cancer cells can still multiply in a hostile environment that lacks proper growth stimuli

Researchers have discovered a novel consequence of loss of the tumour protein p53 that promotes cancer development, according to new findings in eLife. The study in mouse and human cells, from the Netherlands Cancer Institute, suggests that multiplication of cancer cells in the absence of appropriate growth stimuli is supported by the additional loss of

Treatment tied to survival benefit in complex bladder cancer

(HealthDay)—Cancer treatment is associated with a clinically meaningful survival benefit in older, medically complex patients with superficial bladder cancer (SBC), according to a study published online Oct. 5 in Cancer. Tullika Garg, M.D., M.P.H., from Geisinger in Danville, Pa., and colleagues evaluated the association between treatment of SBC and 10-year mortality in 1,800 medically complex

New way to determine whether metastatic cancer cells in breast cancer patients are dormant or soon to turn deadly

For the first time ever, Mount Sinai researchers have identified a protein as a marker that can indicate whether a cancer patient will develop a reoccurrence of lethal, metastatic cancer, according to a clinical study published in Breast Cancer Research in October. The researchers found that when cells from a breast cancer patient’s original tumor

Air pollution may be linked to heightened mouth cancer risk

High levels of air pollutants, especially fine particulate matter (PM2.5) and to a lesser extent, ozone, may be linked to a heightened risk of developing mouth cancer, suggests the first study of its kind, published online in the Journal of Investigative Medicine. The number of new cases, and deaths from, mouth cancer is increasing in

Side effects of radiation for breast cancer: What to know

A doctor may recommend radiation therapy in combination with other treatments, such as surgery and chemotherapy. There are two main types of radiation treatment: External beam radiation: This involves a doctor applying radiation from an external machine to the breast and surrounding tissue. Internal radiation (brachytherapy): This involves placing a small radioactive pellet into the

New cancer vaccine platform a potential tool for tailored and efficacious targeted cancer therapy

Researchers at the University of Helsinki have reported PeptiENV, a cancer vaccine platform that can be used to improve the therapeutic efficacy of oncolytic enveloped viruses currently in clinical use. With the help of this new cancer vaccine platform, the activation of the human immune response against cancer cells becomes significantly more effective. “What is

High-risk HPV linked to improved survival in cervical cancer

The presence of the human high-risk papillomavirus (hrHPV) in the diagnosis of invasive cervical cancer is linked to a greatly improved prognosis compared to cases in which hrHPV cannot be identified in the tumour, according to researchers at Karolinska Institutet in Sweden, who have published their results in the scientific journal PLOS Medicine. The researchers

Bacterial therapy tolerable, shows early promise in patients with advanced solid tumors

A phase I clinical trial investigating the use of bacterial Clostridium novyi-NT spores as an injectable monotherapy had manageable toxicities and showed early clinical efficacy in patients with treatment-refractory solid tumor malignancies, according to data presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3. “Even after a