Tag: Cancer

New clues found to understanding relapse in breast cancer

A large genomic analysis has linked certain DNA mutations to a high risk of relapse in estrogen receptor positive breast cancer, while other mutations were associated with better outcomes, according to researchers from Washington University School of Medicine in St. Louis, the Baylor College of Medicine and the University of British Columbia. The knowledge could

Matcha green tea kills cancer stem cells in tests

Credit: CC0 Public Domain Matcha, the green tea packed with antioxidants, is often hailed as containing properties which prevent disease. Scientists in Salford, UK have shed a ray of light on the claim by testing it on cancer stem cells – with surprising results. In research published in the journal Aging, a team from the

Cancer biology graduate student travels ‘ROCKy’ road toward a cure for post-radiation dry mouth

The United States is in the midst of a head-and-neck cancer epidemic. Although survival rates are relatively high—after treatment with chemotherapy and radiation—survivors can suffer permanent loss of salivary function, potentially leading to decades of health problems and difficulties eating. It is unknown why the salivary gland sometimes cannot heal after radiation damage, but Wen

Mapping out cancer’s movements

Cancer researchers struggle to identify tumor cells that are interspersed within nonmalignant tissues because tumor cells exploit the tissue environment and monopolize available resources to continue growing. Researchers attribute cancer cell’s ability to use cell signaling and metabolic pathways that override normal cell growth restrictions to complicated chemical exchanges between tissue and tumor cells. A

Combination approach shows promise for beating advanced melanoma: New treatment is more effective in people receiving immunotherapy for the first time, study finds

A UCLA-led study has found that a treatment that uses a bacteria-like agent in combination with an immunotherapy drug could help some people with advanced melanoma, an aggressive form of skin cancer, live longer. The research showed that using the immunotherapy drug pembrolizumab and the experimental agent SD-101, a sequence of nucleic acids that mimics

Poor Shared Decision-Making for Lung Cancer Screening

TUESDAY, Aug. 28, 2018 — The quality of shared decision-making (SDM) about the initiation of lung cancer screening (LCS) is poor, according to a study published online Aug. 13 in JAMA Internal Medicine. Alison T. Brenner, Ph.D., M.P.H., from the University of North Carolina at Chapel Hill, and colleagues conducted a qualitative content analysis of

Health Tip: Talking About Your Cancer Diagnosis

— If you’ve been diagnosed with cancer, your family and close friends can be a great source of physical and moral support. The American Cancer Society suggests how to tell loved ones about your diagnosis: Don’t wait to tell them. Sooner or later, they’ll all know. They might feel hurt or left out if they

Keeping cancer out of breath blocks drug resistance

A new combination of existing drugs shows promise that it could reduce the size of cancerous tumors much more effectively than current treatments. As cancer patients know all too well, many highly effective anti-cancer drugs don’t stay effective long. Most tumors will become drug resistant over time as their cells rapidly mutate. Chemists from The

Drop the Word ‘Cancer,’ and Patient Choices Change

THURSDAY, Aug. 23, 2018 — Patients may say no to unnecessary surgery for low-risk thyroid cancer if doctors simply avoid using the word “cancer” when discussing treatment options, a new study suggests. Nearly twice as many people wanted their entire thyroid removed when doctors used the wording “papillary thyroid cancer,” as opposed to a “papillary

Marijuana may improve quality of life in head and neck cancer

(HealthDay)—For patients with newly diagnosed head and neck cancer (HNC), quality of life may improve with marijuana use, according to a study published online Aug. 2 in JAMA Otolaryngology-Head & Neck Surgery. Han Zhang, M.D., from McMaster University in Hamilton, Canada, and colleagues conducted a prospective cohort study involving patients enrolled at the time of

Cancer research: Zombie genes and elephants

Around 17 percent of people die from cancer, but the disease is not a problem restricted to humans; it affects a wide range of species. From cats and dogs to fish and Tasmanian devils — even duck-billed dinosaurs seem to have been afflicted. Interestingly, under 5 percent of elephants in captivity die from cancer. This

Major new vulnerability of childhood leukemia uncovered

Childhood leukemia is a diagnosis that no family ever wants to endure. While the treatment of most types of leukemia has improved steadily over the years, a few specific types remain very difficult to treat. One of these is called “mixed lineage leukemia,” and for children affected by this cancer, their chance of survival is

Kidney cancer’s developmental source revealed: First human kidney cell atlas study across the human lifespan

In the first experiment of its kind, scientists have revealed the precise identity of cancer cells of the most common childhood and adult kidney cancers. Researchers from the Wellcome Sanger Institute, the University of Cambridge, University of Newcastle and their collaborators showed that the cancer cells are versions of specific healthy cells from developing or

Nuclear gatekeeper could block undruggable prostate cancer targets

Certain molecular drivers of cancer growth are “undruggable” — it’s been nearly impossible to develop chemicals that would block their action and prevent cancer growth. Many of these molecules function by passing cancer-promoting information through a gate in the nucleus, where the instructions are carried out. Researchers at the Sidney Kimmel Cancer Center — Jefferson