Tag: Cancer

A Massachusetts General Hospital (MGH) research team has used epigenome editing tools to investigate how the genetic abnormality that drives Ewing sarcoma — the second most common bone cancer in children and young adults — unleashes tumor growth. In their paper in the journal Genes & Development the researchers show that blocking the fusion protein

A new computational model has allowed researchers to identify new therapeutic targets that can attack cancer cells by lowering their intracellular pH. The study, which is the result of collaboration between IRB Barcelona, the Moffitt Cancer Center, and the University of Maryland, has been published in Nature Communications. Cancer cells are known to acidify their

TUESDAY, July 31, 2018 — Colon cancer is treatable if caught early. And sending screening tests in the mail might boost timely detection, a new study suggests. University of North Carolina (UNC) researchers found that Medicaid patients were more likely to get screened if they received stool-testing kits by mail instead of just reminders. “There

Doctors use staging to help diagnose cancer, plan treatment, and explain a person’s outlook clearly. There are four stages, which people often write using Roman numerals. Stage 4 cancer will sometimes appear in writing as stage IV. Knowing what to expect from stage 4 bladder cancer can help people to make informed decisions about their

At the 96th General Session of the International Association for Dental Research (IADR), held in conjunction with the IADR Pan European Regional (PER) Congress, Benjamin Chaffee, University of California, San Francisco, USA gave a poster presentation “Nicotine and Carcinogen Exposure by Tobacco Product Type and Dual-Use.” The IADR/PER General Session & Exhibition is in London,

Women who eat more than the recommended 5 portions of fruit and vegetables a day can reduce their risk of breast cancer by 11% study reveals Broccoli, sprouts, carrots and yellow peppers are the best way to prevent cancer  More than 182,000 women  had an 11 per cent lower risk of breast cancer   Fruit and

In this article, we examine what medullary thyroid cancer or MTC is, and the early signs and common symptoms. We also cover when to see a doctor and the outlook for people with this condition. What is MTC? The American Thyroid Association says that the disease is present in 1–2 percent of cancers of the

Diabetes is a risk factor for all-site cancer for both men and women, but the increased risk is higher in women than in men, according to a new article in Diabetologia (the journal of the European Association for the Study of Diabetes). Cancer is the second leading cause of death in the world. It is

Women who eat a high amount of fruits and vegetables each day may have a lower risk of breast cancer, especially of aggressive tumors, than those who eat fewer fruits and vegetables, according to a new study led by researchers from Harvard T.H. Chan School of Public Health. In their findings, cruciferous vegetables such as

“We don’t just want to find the genes involved in cancer,” says Prof. Yardena Samuels of the Weizmann Institute of Science’s Department of Molecular Cell Biology, “we want to understand what those genes do. We want to reveal the complete picture of a cancer genome.” That is something of a tall order, considering that cells

Professor of Electronic Engineering Andrew Flewitt is working with researchers at the Cancer Research UK (CRUK) Cambridge Centre on a more accurate PSA blood test to detect prostate cancer. At present, the test has limitations for diagnosis and has to be sent off to central labs for the results, a process which can take up

Tackling unsolved problems is a cornerstone of scientific research, propelled by the power and promise of new technologies. Indeed, one of the shiniest tools in the biomedical toolkit these days is the genome editing system known as CRISPR/Cas9. Whitehead Institute Member David Sabatini and his colleagues pioneered the use of this tool as a foundation

A four-protein biomarker blood test improves lung cancer risk assessment over existing guidelines that rely solely upon smoking history, capturing risk for people who have ever smoked, not only for heavy smokers, an international research team reports in JAMA Oncology. “This simple blood test demonstrates the potential of biomarker-based risk assessment to improve eligibility criteria

Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine (IRB Barcelona) report a new mechanism that contributes to the development of inflammation-associated colon cancer and points to new therapeutic targets. The study has been published in the journal EMBO Molecular Medicine. More than a million people worldwide are diagnosed

WEDNESDAY, July 11, 2018 — The attending surgeon is associated with variation in the receipt of genetic testing after breast cancer diagnosis, according to a study published online July 3 in JAMA Surgery. Steven J. Katz, M.D., M.P.H., from the University of Michigan Medical School in Ann Arbor, and colleagues examined the correlation of attending

A team of researchers from Queen Mary University of London have reported the genetic events involved in the early development of bowel cancer in patients with inflammatory bowel disease (IBD). Such knowledge may be able to be exploited to design simple diagnostic tests to stratify patients with IBD at high risk of developing cancer. IBD

Increasingly, doctors are treating lung cancer based on the genetic rearrangements driving the disease. For example, cancers that are driven by changes in the genes ALK, EGFR, and ROS1 can now all be paired with drugs that target these specific changes. However, these cancers are not only dangerous in the lung where they appear, but

A new study of prostate cancer in 202 men, whose cancers had spread and were resistant to standard treatment, found that a surprisingly large number of these cancers — about 17 percent — belong to a deadlier subtype of metastatic prostate cancer. Previously, it was thought that these cancers constituted less than 1 percent of

One of the most important cell types for controlling certain viral infections are natural killer (NK) cells. As part of the innate and rapid immune response, NK-cell recruitment and activation was thought to be a straightforward process. New research shows that NK-cell recruitment and activation requires a rather carefully choreographed interaction of three cell types

A critical link in mapping recurrent mutations of melanoma—the most serious form of skin cancer in humans—has been discovered by researchers at Washington State University School of Molecular Biosciences, in collaboration with researchers at Georgia State University. In a paper published July 6 in Nature Communications, researchers established that DNA binding by a specific set