Tag: Cholesterol

High iron levels may help lower cholesterol: Study

The study, published in the journal PLOS Medicine, looked at the role that iron plays in 900 diseases, uncovering the impact of both low and high iron levels. People with high iron levels are not only protected against anaemia but are also less likely to have high cholesterol, according to a global study. The researchers

It’s OK to indulge once in a while, study suggests: The body adapts to occasional short-term overeating: Body focuses on removing glucose to preserve insulin sensitivity in short-term overeating bout

Overeating has been found to impair blood sugar (glucose) control and insulin levels. A new study suggests that the duration of a bout of overeating can affect how the body adapts glucose and insulin processing when calorie intake increases. The article is published ahead of print in the American Journal of Physiology — Endocrinology and

Scientists propose new theory on Alzheimer’s, amyloid connection

Worldwide, 50 million people are living with Alzheimer’s disease and other dementias. According to the Alzheimer’s Association, every 65 seconds someone in the United States develops this disease, which causes problems with memory, thinking and behavior. It has been more than 100 years since Alois Alzheimer, M.D., a German psychiatrist and neuropathologist, first reported the

Healthy hearts need two proteins working together: Research could be a step toward a treatment to prevent heart attacks

Two proteins that bind to stress hormones work together to maintain a healthy heart in mice, according to scientists at the National Institutes of Health and their collaborators. These proteins, stress hormone receptors known as the glucocorticoid receptor (GR) and mineralocorticoid receptor (MR), act in concert to help support heart health. When the signaling between

New drug could help those with tough-to-treat cholesterol

People whose high cholesterol is resistant to treatment with statin drugs may soon have a new treatment option. This new class of drugs helps block synthesis of artery-clogging cholesterol, researchers explained. The drugs target an enzyme called ATP citrate lyase (ACL), part of the production pathway for “bad” LDL cholesterol in the body. In the

Predictors that determine toxic fats in the liver

Accumulation of fat in the liver, known as fatty liver disease, is experienced by over 5.5 million Australians, including more than 40% of all adults over the age of 50. Fatty liver develops from a combination of both genetic and environmental causes, which influence the age of onset and severity of the disease. Experts are

Drug shows promise to treat diet-induced osteoarthritis

QUT scientists have found that a drug derived from omega-3 fatty acids can reduce osteoarthritis inflammation that’s been caused by a high-fat diet. The study, published in Nature journal Scientific Reports, is among the first to investigate resolvin D1 (RvD1), which has reported anti-inflammatory properties, as a possible treatment for diet-associated osteoarthritis, which affects knees,

Technique boosts omega 3 fatty acid levels in brain 100 fold

Getting enough of the omega 3 fatty acids DHA and EPA into the brain to study their effects on conditions such as Alzheimer’s and depression — which they have been shown to help — is no easy task. While supplements containing these fatty acids exist, there is scant evidence showing that these supplements actually increase

AHA: guidelines stress healthy lifestyle for lowering cholesterol

(HealthDay)—A healthy lifestyle for lowering cholesterol should be emphasized for reducing cardiovascular risk across the life course, according to a guideline published online Nov. 14 in Circulation to coincide with the annual meeting of the American Heart Association, held from Nov. 10 to 12 in Chicago. Scott M. Grundy, M.D., Ph.D., from the University of

Failing heart cells trigger self-protection mechanism: Stress transforms an important structural protein into a gene regulator that protects against heart failure

An unexpected finding that links a structural heart protein to gene regulation following heart stress suggests potential new avenues for developing heart failure therapies. The work led by University of Iowa heart researcher Long-Sheng Song, MD, focuses on a protein called junctophilin-2 (JP2). Previous work from Song’s lab has shown that JP2 is a structural

Updated cholesterol guidelines offer more personalized risk assessment, additional treatment options

More personalized risk assessments and new cholesterol-lowering drug options for people at the highest risk for cardiovascular disease (CVD) are among the key recommendations in the 2018 cholesterol guidelines from the American Heart Association (AHA) and the American College of Cardiology (ACC). The guidelines were presented today at the Association’s 2018 Scientific Sessions conference in

Fasting before a cholesterol test: What to do and what to expect

A cholesterol test measures the amount of cholesterol and triglycerides in a person’s blood. Cholesterol is a fat-like material that is present in all of the body’s cells. The body needs some cholesterol to help produce vitamin D, hormones, and enzymes that aid digestion. A cholesterol test, also known as a lipids panel, measures several