Tag: Cholesterol

Vitamin E found to prevent muscle damage after heart attack

Heart attack is a leading cause of death worldwide and new treatment strategies are highly sought-after. Unfortunately lasting damage to the heart muscle is not uncommon following such an event. Published in Redox Biology, the pre-clinical study sheds new light on the potential of the acute therapy with ?-TOH (vitamin E) in patients presenting with

New cardiac fibrosis study identifies key proteins that translate into heart disease

Using cutting-edge technologies, researchers at Duke-NUS Medical School, Singapore, have developed the first genome-wide dataset on protein translation during fibroblast activation, revealing a network of RNA-binding proteins (RBPs) that play a key role in the formation of disease-causing fibrous tissue in the heart. Their findings, published in the journal Circulation, could help in the search

The diet-microbiome connection in inflammatory bowel disease

Much remains mysterious about the factors influencing human inflammatory bowel disease (IBD), but one aspect that has emerged as a key contributor is the gut microbiome, the collection of microorganisms dwelling in the intestines. Diet is known to profoundly affect this microbial community, and special diets have been used as therapies for intestinal disorders including

Scientists identify potential cause of statin-related muscle pain: Moderate exercise an antidote to known statin side effect

An international team of BHF-funded researchers may have discovered why some people experience muscle pain after taking statins. The research, published in JACC: Basic to Translational Science, could help doctors prevent a known side effect of statins and ensure people are able to reap the benefits of the life-saving drugs. According to the research, statins

New, healthier ‘butter’ spread almost entirely water

Cornell University food scientists have created a new low-calorie ‘butter’ spread that consists mostly of water. A tablespoon of this low-calorie spread has 2.8 grams of fat and 25.2 calories. Butter, on the other hand, which is 84% fat and about 16% water, has about 11 grams of fat and nearly 100 calories. They figured

Long-term statin use associated with lower glaucoma risk: Study finds that people who used statins for five years or more had a 21 percent lower chance of primary open-angle glaucoma

A new study brings the connection between statin use and risk of glaucoma into sharper focus. Investigators from Brigham and Women’s Hospital have found that using statins for five or more years is associated with lower risk of primary open-angle glaucoma. Results of the study were published recently in JAMA Ophthalmology. Glaucoma, a leading cause

High iron levels may help lower cholesterol: Study

The study, published in the journal PLOS Medicine, looked at the role that iron plays in 900 diseases, uncovering the impact of both low and high iron levels. People with high iron levels are not only protected against anaemia but are also less likely to have high cholesterol, according to a global study. The researchers

It’s OK to indulge once in a while, study suggests: The body adapts to occasional short-term overeating: Body focuses on removing glucose to preserve insulin sensitivity in short-term overeating bout

Overeating has been found to impair blood sugar (glucose) control and insulin levels. A new study suggests that the duration of a bout of overeating can affect how the body adapts glucose and insulin processing when calorie intake increases. The article is published ahead of print in the American Journal of Physiology — Endocrinology and

Scientists propose new theory on Alzheimer’s, amyloid connection

Worldwide, 50 million people are living with Alzheimer’s disease and other dementias. According to the Alzheimer’s Association, every 65 seconds someone in the United States develops this disease, which causes problems with memory, thinking and behavior. It has been more than 100 years since Alois Alzheimer, M.D., a German psychiatrist and neuropathologist, first reported the

Healthy hearts need two proteins working together: Research could be a step toward a treatment to prevent heart attacks

Two proteins that bind to stress hormones work together to maintain a healthy heart in mice, according to scientists at the National Institutes of Health and their collaborators. These proteins, stress hormone receptors known as the glucocorticoid receptor (GR) and mineralocorticoid receptor (MR), act in concert to help support heart health. When the signaling between

New drug could help those with tough-to-treat cholesterol

People whose high cholesterol is resistant to treatment with statin drugs may soon have a new treatment option. This new class of drugs helps block synthesis of artery-clogging cholesterol, researchers explained. The drugs target an enzyme called ATP citrate lyase (ACL), part of the production pathway for “bad” LDL cholesterol in the body. In the

Predictors that determine toxic fats in the liver

Accumulation of fat in the liver, known as fatty liver disease, is experienced by over 5.5 million Australians, including more than 40% of all adults over the age of 50. Fatty liver develops from a combination of both genetic and environmental causes, which influence the age of onset and severity of the disease. Experts are