Tag: chronic

How chronic inflammation may drive down dopamine and motivation

Growing evidence shows that the brain’s dopamine system, which drives motivation, is directly affected by chronic, low-grade inflammation. A new paper proposes that this connection between dopamine, effort and the inflammatory response is an adaptive mechanism to help the body conserve energy. Trends in Cognitive Sciences published the theoretical framework developed by scientists at Emory

Depression, obesity and pain could be treated by targeting one protein

Depression, obesity and chronic pain could all be treated ‘by blocking the SAME protein’ Scientists blocked protein FKBP51 for the first time without also affecting others Hope will lead to treatment in humans; FKBP51 is also being tested in cancer FKBP51 has many functions from regulating glucose to stress management  e-mail 8 View comments Depression, obesity

Ovary removal may increase risk of chronic kidney disease

Premenopausal women who have their ovaries surgically removed face an increased risk of developing chronic kidney disease, according to a Mayo Clinic study published on Wednesday, Sept. 19, in the Clinical Journal of the American Society of Nephrology. “This is the first study that has shown an important link between estrogen deprivation in younger women

Chronic pain may be an important contributor to suicide

Chronic pain may be an important contributor to suicide. Nearly 9 percent of people who died by suicide in 18 states from 2003 to 2014 had documentation of chronic pain in their incident records. Findings from the National Violent Death Reporting System (NVDRS) are published in Annals of Internal Medicine. More than 25 million adults

AMP addresses clinical relevance of DNA variants in chronic myeloid neoplasms

The Association for Molecular Pathology (AMP), the premier global molecular diagnostics professional society, today published consensus, evidence-based recommendations to aid clinical laboratory professionals with the management of most Chronic Myeloid Neoplasms (CMNs) and development of high-throughput pan-myeloid sequencing testing panels. The report, “Clinical Significance of DNA Variants in Chronic Myeloid Neoplasms (CMNs): A Report of

New approach to treating chronic itch

Researchers at the University of Zurich have discovered a new approach to suppressing itch by targeting two receptors in the spinal cord with the right experimental drug. In a series of experiments in mice and dogs, they successfully alleviated different forms of acute as well as chronic itch. For the chronic itch, current treatment options

Quantity over quality—larger muscles could compensate for poor muscle quality in chronic kidney disease patients

The size of muscles in patients suffering from chronic kidney disease (CKD) could be more important to maintaining good physical performance than muscle quality, new research has shown. In a paper published in the journal Nephrology Dialysis Transplantation, researchers from the University of Leicester have found that patients with large muscles had better physical function,

Researchers say chronic dizziness can result from, or trigger, psychiatric disorders

While most cases of chronic dizziness result from a physical disorder, psychiatric issues can be a cause—or a consequence—of chronic dizziness, according to research published The Journal of the American Osteopathic Association. Chronic dizziness can result from a number of underlying health problems, most commonly involving neurologic, vestibular and cardiac diseases. For patients who have