Tag: Controlled Substances

Gold-complexed ferrocenyl phosphines as potent antimalarials

A team of researchers from the Singapore University of Technology and Design (SUTD) and Nanyang Technological University (NTU) have developed novel ferrocene-based molecules that impair the malaria parasite’s metabolic function leading to parasite death. Despite concerted efforts for malaria elimination, this deadly disease remains a major health threat to the developing world. The causative agent

New insights into the neural risks and benefits of marijuana use: Compounds in cannabis can impair or improve memory depending on age, disease

Research released today underscores both the dangers and the therapeutic promise of marijuana, revealing different effects across the lifespan. Marijuana exposure in the womb or during adolescence may disrupt learning and memory, damage communication between brain regions, and disturb levels of key neurotransmitters and metabolites in the brain. In Alzheimer’s disease, however, compounds found in

Marijuana found in breast milk up to six days after use: Researchers report 63 percent of breast milk samples from mothers using marijuana contained traces of the drug

With the legalization of marijuana in several states, increased use for both medicinal and recreational purposes has been documented in pregnant and breastfeeding women. Although national organizations like the American Academy of Pediatrics recommend that breastfeeding mothers do not use marijuana, there has been a lack of specific data to support health or neurodevelopmental concerns

Clinical trials in a dish: A perspective on the coming revolution in drug development

A new SLAS Discovery article available now for free ahead-of-print, offers perspective from researchers at Coyne Scientific (Atlanta, GA) about Clinical Trials in a Dish (CTiD), a novel strategy that bridges preclinical testing and clinical trials. The pharmaceutical industry is facing unprecedented challenges as the cost of developing new drugs reaches unsustainable levels, fueled in

Prescription drug monitoring programs may have negative unintended consequences: Study shows programs may be linked to fatal drug overdoses

Prescription drug monitoring programs (PDMPs) are a key component of the President’s Prescription Drug Abuse Prevention Plan and considered a critical tool for reducing prescription opioid-related illness and death. The results of a study just conducted at Columbia University’s Mailman School of Public Health and University of California, Davis, show there is insufficient evidence to

New carbon-dioxide-adsorbing crystals could form the basis of future biomedical materials that rely on the shape-memory effect

Kyoto University scientists are one step closer to designing porous materials that can change and retain their shapes — a function known as shape-memory effect. Shape-memory materials have applications in many fields. For example, they could be implanted in the body and then induced to change shape for a specific function, such as serving as