Tag: develop

Scientists develop a new method to detect light in the brain

Researchers from Istituto Italiano di Tecnologia (IIT) and University of Salento, both in Lecce, Italy, and Harvard Medical School in Boston have developed a new light-based method to capture and pinpoint the epicenter of neural activity in the brain. The approach, described in Nature Methods, lays the foundation for novel ways to map connections across

Researchers develop a faster, stronger rabies vaccine

Every year, more than 59,000 people around the world die of rabies and there remains no cheap and easy vaccine regimen to prevent the disease in humans. Now, researchers report in PLOS Neglected Tropical Diseases that adding a specific immune molecule to a rabies vaccine can boost its efficacy. Previous studies have suggested that the

How self-reactive immune cells are allowed to develop

Directly after birth, the immune system completes production of a subtype of antibody-producing immune cells, B-1, that are to last for a lifetime. No more B1 cells are formed after that point. However, these cells are self-reactive—they produce not only antibodies against foreign substances, but also against the body’s own substances, and it is unclear

Researchers develop innovative treatment for familial adenomatous polyposis

Researchers from Tel Aviv University and Tel Aviv Sourasky Medical Center (Ichilov Hospital) have developed an innovative drug treatment for familial adenomatous polyposis (FAP), a rare, inherited condition that affects adolescents and young adults and often leads to colorectal cancer. The novel drug, based on antibiotics, inhibits the development of intestinal polyps that, left untreated,

Researchers first to develop comprehensive models of ‘seeds and soil’ as a means to combat breast cancer metastasis

Scientists at VCU Massey Cancer Center have identified key biological pathways that regulate the spread of tumor cells to vital organs. These findings may have a significant influence on the development of new therapies that slow or prevent breast cancer metastasis. Metastasis refers to the spread of cancer cells to other organs, and the likelihood

Varicose veins unlikely to develop into blood clots

Similar to leaky pipes, veins, as they return blood to the heart, sometimes fail to close completely. They stretch out and subsequently leak near the surface of the skin, creating spider or varicose veins that may cause discomfort. Dr. Tanya Flohr, a vascular surgeon at Penn State Heart and Vascular Institute, said the majority of

How damaging immune cells develop during tuberculosis

Insights into how harmful white blood cells form during tuberculosis infection point to novel targets for pharmacological interventions, according to a study published in the open-access journal PLOS Pathogens by Valentina Guerrini and Maria Laura Gennaro of Rutgers New Jersey Medical School, and colleagues. Foam cells are a type of white blood cell, known as

Researchers develop new models for predicting suicide risk

Combining data from electronic health records with results from standardized depression questionnaires better predicts suicide risk in the 90 days following either mental health specialty or primary care outpatient visits, reports a team from the Mental Health Research Network, led by Kaiser Permanente research scientists. The study, “Predicting Suicide Attempts and Suicide Death Following Outpatient

Scientists develop novel technique to study brain disease

A new tool developed by researchers at the National Institutes of Health has determined, for the first time, how two distinct sets of neurons in the mouse brain work together to control movement. The method, called spectrally resolved fiber photometry (SRFP), can be used to measure the activity of these neuron groups in both healthy