Tag: disease

An omega-6 fatty acid could help in fight against heart disease

An omega-6 polyunsaturated fatty acid has the potential to help fight heart disease, finds a new study by researchers at Cardiff University, in collaboration with Ben-Gurion University of the Negev. With funding from the British Heart Foundation, the team found that dihomo-gamma-linolenic acid (DGLA), an omega-6 polyunsaturated fatty acid, could halt the progression of atherosclerosis—one

Alzheimer’s drug trial targets by-product of gum disease

The pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer’s drug that targets toxic substances released by P. gingivalis, a bacteria linked to gum disease. In a poster presented at the Alzheimer’s Association International Conference today (Wednesday, July 17), researchers provided an overview of the development of the drug, known as COR388, and

Alzheimer’s disease: Sex affects tau accumulation in the brain

The strongest genetic risk factor for Alzheimer’s disease is the apolipoprotein E type 4 allele (ApoE ε4). Research presented by Manish Paranjpe at the 2019 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) used positron emission tomography (PET) to show that women who are ApoE ε4 carriers and already experiencing mild

A new molecular mechanism could explain the origins of the depressive symptoms in Huntington’s disease

About 40 percent of the affected patients with Huntington’s disease—a neurodegenerative pathology- show depression symptoms, even in early stages before the apparition of the typical motor symptoms of the disease. An altered function of Cdk5 kinase—an essential enzyme in several cell signalling pathways- could explain the physiopathology of the depressive-like behaviour in Huntington’s disease, according

Sniffing out disease with smartphones

Gastric cancer, also known as stomach cancer, is the fifth most common cause of cancer-related deaths in Europe. Because of the lack of early signs specifically related to the disease, it’s usually only detected at an advanced stage—when treatment is for the most part ineffective. Driven to improve stomach and other cancer survival rates, for

Everything you need to know about Lyme disease

(HealthDay)—With growing concern about mosquito-borne viruses such as Zika, it’s easy to let down your guard when it comes to ticks. But Lyme disease is still a danger, especially in the Northeast and upper Midwest. In fact, it has affected people in almost every state. Lyme disease is spread through the bite of an infected

Novel treatments offer new hope for patients with autoimmune disease

Autoimmune diseases, including type 1 diabetes and multiple sclerosis, arise when the body’s immune cells attack itself. Current treatments eliminate these misfunctioning immune cells, but also destroy normal, protective immune cells, leaving patients susceptible to immune deficiency and opportunistic infections. Researchers at University of Utah Health have developed a new approach that targets the misfunctioning

Small Trial Provides New Hope Against Parkinson’s Disease

FRIDAY, March 1, 2019 — It may be possible to restore brain cells damaged by Parkinson’s disease and reverse a patient’s condition, something no current treatment can do, according to British researchers who conducted potentially groundbreaking clinical trials. They cautioned the trial was small — just 41 patients — and the research is still in

Coeliac disease can cause irreversible changes to immune cells

Immune cells in the bowel of people who suffer with coeliac disease are permanently replaced by a new subset of cells that promote inflammation, suggests a new study involving researchers at Cardiff University. This permanent ‘immunological scarring’ lays the foundation for the disease to progress and could have long-term implications for gut health in affected