Tag: Disorders and Syndromes

Take a bath 90 minutes before bedtime to get better sleep

Biomedical engineers at The University of Texas at Austin may have found a way for people to get better shuteye. Systematic review protocols — a method used to search for and analyze relevant data — allowed researchers to analyze thousands of studies linking water-based passive body heating, or bathing and showering with warm/hot water, with

Differences in MS patients’ cerebrospinal fluid may be key to drugs that halt progression

The disability burden for people with multiple sclerosis (MS) can vary significantly depending on whether they have a relapsing/remitting form of the disease, where they experience periods of clinical remission, or a progressive form, where they have continued neurological deterioration without clinical remission. Effective therapies exist for managing relapsing/remitting MS, but treatment for progressive MS

Looking at how the brain reacts to boredom could help people cope

Boredom is a common human experience. But how people cope with or handle being bored is important for mental health. “Everybody experiences boredom,” said Sammy Perone, Washington State University assistant professor in the Department of Human Development. “But some people experience it a lot, which is unhealthy. So, we wanted to look at how to

How inhaled fungal spores cause fatal meningitis

Pathogenic fungal spores capitalize on host immune cells to escape the lung and gain access to the brain to cause fatal disease in mice, according to a study published June 27 in the open-access journal PLOS Pathogens by Christina Hull of the University of Wisconsin-Madison, and colleagues. These insights into the interactions between pathogenic fungal

ALS patients may benefit from more glucose

Increased glucose, transformed into energy, could give people with amyotrophic lateral sclerosis, or ALS, improved mobility and a longer life, according to new findings by a University of Arizona-led research team. Physicians have long known that people with ALS experience changes in their metabolism that often lead to rapid weight loss in a process called

A new drug target for chemically induced Parkinson’s disease

More than three decades ago, scientists discovered that a chemical found in a synthetic opioid, MPTP, induced the onset of a form of Parkinson’s disease. In a new study led by scientists from the School of Veterinary Medicine, researchers found that an enzyme in the body can metabolize compounds formed in the brain from alkaloids

Fishing a line coupled with clockwork for daily rhythm: Molecular mechanism of the interplay of clock proteins for generating a circadian oscillation

Organisms on this planet, including human beings, exhibit a biological rhythm that repeats about every 24 h to adapt to the daily environmental alteration caused by the rotation of the earth. This circadian rhythm is regulated by a set of biomolecules working as a biological clock. In cyanobacteria (or blue-green algae), the circadian rhythm is

Antibiotics that dentists prescribe are unnecessary 81% of the time

Antibiotics prescribed by dentists as a preemptive strike against infection are unnecessary 81% of the time, according to a study published today in JAMA Network Open. The findings are important because dentists are responsible for 10% of all antibiotic prescriptions written in the United States. Antibiotics prescribed when not warranted expose patients to the risk

Broken brain cells repaired in dementia mouse model: If translated to humans, results suggest new directions for combating cognitive decline in elderly

Dysfunctional neurons in the hippocampus of adult female mice modeling dementia can be repaired and reconnected to distant parts of the brain, reports a new study published in JNeurosci. The similarity between the mouse model and the human condition underscores the therapeutic potential of targeting these cells in dementia patients. The hippocampus generates new brain

Exercise: Psych patients’ new primary prescription

When it comes to inpatient treatment of a range of mental health and mood disorders — from anxiety and depression to schizophrenia, suicidality and acute psychotic episodes — a new study advocates for exercise, rather than psychotropic medications, as the primary prescription and method of intervention. Findings from the study reveal that physical exercise is

Brain network activity can improve in epilepsy patients after surgery

Successful epilepsy surgery can improve brain connectivity similar to patterns seen in people without epilepsy, according to a new study published in the journal Neurosurgery. The Vanderbilt University Medical Center (VUMC) study of 15 people with temporal lobe epilepsy is the first to show improvements in brain networks after surgery compared to a group of

Older adults expect to lose brain power, but most don’t ask doctors how to prevent dementia: Many in their 50s and early 60s buy supplements or do puzzles in hopes of protecting brain health, but may miss out on effective strategies

Many Americans in their 50s and early 60s are worried about declining brain health, especially if they have loved ones with memory loss and dementia, a new national poll finds. But while the majority of those polled say they take supplements or do puzzles in an effort to stave off brain decline, very few of

Appendix removal associated with development of Parkinson’s disease: Data from 62 million records explores relationship between the gut and the nervous system disorder

Patients who had their appendix removed were more likely to develop Parkinson’s disease than those whose appendix remained in place, according to the largest study to address the relationship between the two conditions. The retrospective study involving more than 62 million patient records from 26 health systems will be presented at Digestive Disease Week® (DDW)

Anger more harmful to health of older adults than sadness: Associated with increased inflammation, which can lead to chronic disease, study says

Anger may be more harmful to an older person’s physical health than sadness, potentially increasing inflammation, which is associated with such chronic illnesses as heart disease, arthritis and cancer, according to new research published by the American Psychological Association. “As most people age, they simply cannot do the activities they once did, or they may

Connecting neurons in the brain

The brain consists of a large collection of interconnected neurons. How complex patterns of neuronal cells grow into functioning circuits during development has fascinated researchers for decades. A team of scientists at VIB and KU Leuven has now uncovered a new signaling mechanism in fruit flies that specifies the formation of neuronal circuits in the

Researchers define Alzheimer’s-like brain disorder: LATE symptoms resembles Alzheimer’s disease but has different cause

A brain disorder that mimics symptoms of Alzheimer’s disease has been defined with recommended diagnostic criteria and guidelines for advancing future research on the condition. Researchers at Rush University Medical Center and scientists from several National Institutes of Health-funded institutions, in collaboration with international peers, described the newly-named pathway to dementia, Limbic-predominant Age-related TDP-43 Encephalopathy,

Early lipids boost brain growth for vulnerable micro-preemies

Dietary lipids, already an important source of energy for tiny preemies, also provide a much-needed brain boost by significantly increasing global brain volume as well as increasing volume in regions involved in motor activities and memory, according to research presented during the Pediatric Academic Societies 2019 Annual Meeting. “Compared with macronutrients like carbohydrates and proteins,