Tag: Disorders and Syndromes

In a study of mice, National Institutes of Health-funded researchers describe a new circuit involved in fine-tuning the brain’s decision either to hide or confront threats. The study, published in Nature, was partially funded by the NIH’s Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative. “Being able to manipulate specific circuits can uncover surprising relationships

Scientists have shone new light on how the human brain uses past experiences and generalizes them to future events, helping us safely navigate the world around us, a study in eLife reveals. Our ability to ‘generalize’ is an important survival technique, but over-generalizing from bad events could explain why some people fear and then avoid

Scientists at The Scripps Research Institute have devised what they call a “neuronal cookbook” for turning skin cells into different types of neurons. As reported today in the journal Nature, the research opens the door to studying common brain conditions such as autism, schizophrenia, addiction and Alzheimer’s disease under reproducible conditions in a dish. “The

Blurry and clear versions of an image are represented similarly in the brain, according to a neuroimaging study published in eNeuro. The research shows how the visual system fills in missing information to maintain perception when visibility is low. Vision arises from a “bottom-up” process that transduces light into neural signals and a “top-down” process

During a stroke or an epileptic seizure, neurons in affected parts of the brain fire at an abnormally rapid rate. One byproduct of this condition is that the pH of the brain drops markedly, rendering the local environment inhospitably acidic. Using a powerful microscopy method called cryo-EM, biologists at Cold Spring Harbor Laboratory (CSHL) have

Neuroscience has studied music for decades, and it has been found to activate both the cortical and deeper brain areas. Neuroscience of dance, instead, is a young but quickly growing field. In her doctoral dissertation, Master of Science Hanna Poikonen developed methods for understanding the processes that dance generates in the cortex at the Cognitive

If 95 percent of your neighbors are chatty and outgoing, you probably know more about them than the 5 percent who are reclusive and shy. It’s similar for neuroscientists who study the striatum, a brain region associated with action control and learning: they know a lot more about the 95 percent of neurons that communicate

Preliminary research using mcDESPOT magnetic resonance imaging shows changes in the myelin content of white matter in the brain following mild traumatic brain injury. Myelin changes are apparent at the time of injury and 3 months afterward. For more details, see the article, “Prospective study of myelin water fraction changes after mild traumatic brain injury

Researchers have found evidence that acupuncture could help people who experience dental anxiety. Dental anxiety affects up to an estimated 30% of the adult population in countries world-wide. Patients can experience nausea, difficulty breathing and dizziness at the thought of going to the dentist, during an examination, and following treatment. Reasons behind dental anxiety can

Research published today (Tuesday 1 May) has revealed new clues which might help explain why young people with the most severe forms of antisocial behaviour struggle to control and regulate their emotions, and might be more susceptible to developing anxiety or depression as a result. The study, published in the journal Social Cognitive and Affective

Alzheimer’s disease currently affects more than 5.5 million Americans and is one of the costliest diseases to treat, according to the Alzheimer’s Association. Characterized by a buildup of plaque in the brain, few animal models exist that researchers could use to study this devastating disorder. Now, a team of researchers from the University of Missouri,

A collaborative team of researchers at McLean Hospital, a Harvard Medical School affiliate, and Oxford University has found that elevated levels of certain types of lipids (fat molecules) in the brain may be an early sign of Parkinson’s disease (PD). This finding could have significant implications for identifying patients who may be at risk for

The cerebral neocortex is responsible for higher brain functions, such as conscious thought and language, in humans. In the neocortex, neurons are precisely arranged in an ordered 6-layered structure. This neocortical structure is formed by the sequential generation of billions of neurons and their migration toward the brain surface in the fetal period. “Subplate neurons”

Using drug repurposing, a team of researchers led by animal biologists at Nagoya University has discovered compounds that can either shorten or lengthen the circadian rhythm in human cells. A hormone, also known as a common anti-aging supplement demonstrated period-shortening activities, and when it was fed to mice, jet lag symptoms were significantly reduced. Further

Researchers at the Center for Cognition and Sociality, within the Institute for Basic Science (IBS), have just published in Neuron about a genetic variant that controls and increases empathy-driven fear in mice. As empathy is evolutionarily conserved from rodents to humans, this finding might contribute to clarify individual variability in neuropsychiatric conditions characterized by empathic

Researchers at University of California San Diego School of Medicine have determined that psychological resilience has a positive effect on health outcomes for people living with schizophrenia. This is the first study to quantitatively assess the effects of both childhood trauma and psychological resilience on health and metabolic function in people living with schizophrenia. Globally

While global rates of mental disorders in children have remained stable over time, the decline of infectious diseases will place mental disorders among the main causes of disease in children aged 4-15 years, according to a study published in the open access journal Child and Adolescent Psychiatry and Mental Health. Marie-Laure Baranne and Bruno Falissard

Patients with Alzheimer’s disease and other forms of dementia commonly experience the sundown syndrome — a sudden worsening of confusion, agitation and aggression at the end of the day. Its daily pattern suggested that “sundowning,” as the phenomenon is also known, may be governed by the body’s internal biological clock. Synchronized by light and darkness,

Researchers at USC and Harvard have developed a new approach to repair cells deep inside the ear — a potential remedy that could restore hearing for millions of elderly people and others who suffer hearing loss. The lab study demonstrates a novel way for a drug to zero in on damaged nerves and cells inside

Modern neuroscience, for all its complexity, can trace its roots directly to a series of pen-and-paper sketches rendered by Nobel laureate Santiago Ramón y Cajal in the late 19th and early 20th centuries. His observations and drawings exposed the previously hidden composition of the brain, revealing neuronal cell bodies and delicate projections that connect individual