Tag: down

Neurobiology: To keep pain in check, count down

Is the heat still bearable, or should I take my hand off the hotplate? Before the brain can react appropriately to pain, it must evaluate and integrate sensory, cognitive and emotional factors that modulate the perception and processing of the sensation itself. This task requires the exchange of information between different regions of the brain.

Antihistamines and similar drugs could slow down Huntington’s disease

Scientists have described a potential new therapeutic strategy for slowing down early-stage Huntington’s disease in a new study published today in eLife. The research in mice indicates that targeting the histamine H3 receptor (H3R) – a well-established drug target for other conditions such as hay fever—could help to prevent imbalances in dopamine signaling that lead

How chronic inflammation may drive down dopamine and motivation

Growing evidence shows that the brain’s dopamine system, which drives motivation, is directly affected by chronic, low-grade inflammation. A new paper proposes that this connection between dopamine, effort and the inflammatory response is an adaptive mechanism to help the body conserve energy. Trends in Cognitive Sciences published the theoretical framework developed by scientists at Emory

Enzyme that breaks down amino acids may promote aging

Permanently arrested cell growth is known as “cellular senescence”, and the accumulation of senescent cells may be one cause of aging in our bodies. Japanese researchers have discovered that a certain enzyme in our bodies promotes cellular senescence by producing reactive oxygen species. Drugs that target this enzyme could potentially suppress this process, and inhibit

Smart pills dumb down medical care, experts warn

Enthusiasm for an emerging digital health tool, the smart pill, is on the rise but researchers at the University of Illinois at Chicago have published a paper in the American Journal of Bioethics that cautions health care providers and policymakers to slow down when it comes to allowing this technology in patient care settings. Smart

Busy Philipps Shut Down a Mom-Shamer With This Spot-On Response

Mom of two Busy Philipps is not here for men body-shaming her (or anyone) on Instagram. The actor recently shared a gym selfie on apothekegenerika.de Instagram for #TheAwesomeChallenge, a program that donates clothes to kids in need every time the hashtag is used. But of course, some internet troll had to take a post about charity

Flip a switch and shut down seizures? New research suggests how to turn off out-of-control signaling in the brain

The brain is a precision instrument. Its function depends on finely calibrated electrical activity triggering the release of chemical messages between neurons. But sometimes the brain’s careful balance is knocked out of control, as in epilepsy. Electroencephalography, or EEG, visualizes a brain’s electrical activity and can reveal how an epileptic seizure diverges from the predictable

Your Ultimate Guide To Slim Down In Just 7 Days

1. Change up your HIIT sessions – HIIT has gotten a big reputation for burning off those annoying fat spots, but your body can get used to it if you are doing the same HIIT exercise day in/day out! There are so many options out there – so every couple of weeks, shock your body

FDA cracks down on caffeine-loaded supplements

(HealthDay)—The U.S. Food and Drug Administration announced Friday that it has issued tough new restrictions on the sale of dietary supplements that contain dangerously high amounts of caffeine. Supplements that contain pure or highly concentrated caffeine in powder or liquid forms are no longer permitted to be sold in bulk quantities directly to consumers, the

Combination of medications slows down brain tumours in children

In collaboration with a number of American colleagues, researchers from Uppsala University have found an Achilles’ heel for the most common form of malignant child brain tumours. By combining two kinds of medicines, it is possible to simultaneously attack the cancer cell’s division and its reinforcement system, which is necessary in order for treatment to