Tag: epilepsy

Molecular mechanisms of ancient herbal remedies: Components of leaf extract prove highly effective at preventing life-threatening seizures

Researchers in the Department of Physiology & Biophysics at the University of California, Irvine School of Medicine have discovered the molecular basis for a therapeutic action of an ancient herbal medicine used across Africa to treat various illnesses, including epilepsy. The herbal medicine, a leaf extract from the shrub Mallotus oppositifolius, was previously found to

Heart-brain connection could be predictive biomarker for epilepsy

Heartbeat irregularities connected to brain activity abnormalities may lead to the ability to predict eventual epileptic seizures in subjects who suffered physical or infectious brain insults, according to Penn State researchers who studied mouse models of cerebral malaria, which often causes epilepsy in those who survive. “We were developing, in a project led by Steven

Spider venom strikes a blow against childhood epilepsy

A devastating form of childhood epilepsy that is resistant to traditional drugs may have met its match in spider venom. Researchers from The University of Queensland and the Florey Institute of Neuroscience and Mental Health discovered that a peptide in spider venom can restore the neural deficiencies that trigger seizures associated with Dravet syndrome. UQ

Insight without incision: Advances in noninvasive brain imaging offers improvements to epilepsy surgery

About a third of epilepsy sufferers require treatment through surgery. To check for severe epilepsy, clinicians use a surgical procedure called electrocorticography (ECoG). An ECoG maps a section of brain tissue to help clinicians identify areas damaged by seizures. “But ECoG requires taking a part of your skull out and putting electrodes directly on brain

Research reveals underappreciated role of brainstem in epilepsy

New research from Vanderbilt suggests that repeated seizures reduce brainstem connectivity, a possible contributor to unexplained neurocognitive problems in epilepsy patients. The brainstem has been rarely studied in epilepsy because seizures typically originate in the temporal lobe or other areas of the cortex. Noting that people with temporal lobe epilepsy often lose consciousness even though

During disasters, active Twitter users likely to spread falsehoods: Study examines Boston Marathon bombing, Hurricane Sandy; also finds most users fail to correct misinformation

We know that Twitter is littered with misinformation. But how good are the social media platform’s most active users at detecting these falsehoods, especially during public emergencies? Not good, according to new University at Buffalo research that examined more than 20,000 tweets during Hurricane Sandy and the Boston Marathon bombing. The study, published today (May

Repairing a leaky blood-brain barrier in epilepsy

Blocking the activity of an enzyme that has a key role in the generation of recurring seizures may provide a new way to treat epilepsy that is resistant to anti-seizure drugs, according to a study of rats and mice published in JNeurosci. One-third of people with epilepsy, one of the most common neurological disorders, do