Tag: Fibrosis

Most patients with cystic fibrosis may receive insufficient antibiotics to fight lung infections

The majority of patients with cystic fibrosis may not achieve blood concentrations of antibiotics sufficiently high enough to effectively fight bacteria responsible for pulmonary exacerbations, leading to worsening pulmonary function, indicates a study led by researchers at Children’s National Health System. Additionally, the study findings show that it’s impossible to predict solely from dosing regimens

New hope for cystic fibrosis

A new triple-combination drug treatment being trialled at the Mater Hospital in Brisbane could increase the life expectancy of patients with cystic fibrosis. Mater Research Institute-University of Queensland (MRI-UQ) researcher Dr. Lucy Burr said seven patients were enrolled in Phase 2 of the clinical trial, which aimed to treat the underlying cause of cystic fibrosis.

3-Drug Therapy Might Be Cystic Fibrosis ‘Breakthrough’

THURSDAY, Oct. 18, 2018 — In what researchers are calling a “breakthrough,” two preliminary trials have found that either of two triple-drug regimens could potentially benefit 90 percent of people with cystic fibrosis. The trials were short-term, finding that the drug combinations improved adult patients’ lung function over four weeks. But experts said they were

TGFB1 Mutation Ups Radiation-Induced Breast Fibrosis Risk

THURSDAY, Aug. 2, 2018 — The C-509T allele in the promoter region of transforming growth factor β (TGFB1) is associated with radiation-induced breast fibrosis risk among patients with early-stage breast cancer, according to study published online July 19 in JAMA Oncology. Aaron J. Grossberg, M.D., Ph.D., from the University of Texas MD Anderson Cancer Center