Tag: Heart Disease

Heart disease is a condition in which the coronary arteries, the major blood vessels that supply the heart with blood, get clogged up with deposits of cholesterol known as plaques. Before a heart attack, one of the plaques ruptures, causing a blood clot, and this may block the supply of blood to the heart, triggering

About one in three diabetic patients develops diabetic retinopathy (DR), which can impair vision and lead to blindness. A new study in The American Journal of Pathology, published by Elsevier, provides clear evidence that high glucose increases the levels of enzymatic precursor — lysyl oxidase propeptide (LOX-PP) — that promotes cell death, which was verified

Heart attack is a leading cause of death worldwide and new treatment strategies are highly sought-after. Unfortunately lasting damage to the heart muscle is not uncommon following such an event. Published in Redox Biology, the pre-clinical study sheds new light on the potential of the acute therapy with ?-TOH (vitamin E) in patients presenting with

Using cutting-edge technologies, researchers at Duke-NUS Medical School, Singapore, have developed the first genome-wide dataset on protein translation during fibroblast activation, revealing a network of RNA-binding proteins (RBPs) that play a key role in the formation of disease-causing fibrous tissue in the heart. Their findings, published in the journal Circulation, could help in the search

A new vaccine developed by Griffith University Institute for Glycomics researchers has the potential to treat and prevent toxic shock caused by invasive streptococcal disease, which kills more than 160,000 people every year. “Streptococcal toxic shock syndrome is an acute condition like meningococcus — if you get exposed to the organism you can be dead

Exercise is known to reduce blood pressure — but the activity of bacteria in our mouths may determine whether we experience this benefit, according to new research. An international team of scientists has shown that the blood pressure-lowering effect of exercise is significantly reduced when people rinse their mouths with antibacterial mouthwash, rather than water

Smoking e-cigarettes, also called vaping, has been marketed as a safe alternative to tobacco cigarettes and is rising in popularity among non-smoking adolescents. However, a single e-cigarette can be harmful to the body’s blood vessels — even when the vapor is entirely nicotine-free — according to a new study by researchers in the Perelman School

Canadian researchers have discovered that covert — or ‘silent’ — strokes are common in seniors after they have elective, non-cardiac surgery and double their risk of cognitive decline one year later. While an overt stroke causes obvious symptoms, such as weakness in one arm or speech problems that last more than a day, a covert

On an ice hockey team, the players all start off with identical uniforms, skates and a stick. But if you take one of them, add padding, a glove, and a mask; and switch the stick to one with a larger blade, then you get a goalie. Now, the player has morphed — or differentiated —

Researchers at Lund University in Sweden have investigated the link between osteoarthritis and mortality in an epidemiological study. It was shown that the risk of dying from cardiovascular disease was higher for people with osteoarthritis than for the rest of the population. Using population registers, the researchers studied approximately 469,000 people living in Skåne, Sweden,

Salt intake in China is confirmed to be among the highest in the world, with adults over the past four decades consistently consuming on average above 10g of salt a day, which is more than twice the recommended limit, according to new research led by Queen Mary University of London. The systematic review and meta-analysis,

A new study brings the connection between statin use and risk of glaucoma into sharper focus. Investigators from Brigham and Women’s Hospital have found that using statins for five or more years is associated with lower risk of primary open-angle glaucoma. Results of the study were published recently in JAMA Ophthalmology. Glaucoma, a leading cause

Almost 500,000 Americans die each year from cardiac arrest, when the heart suddenly stops beating. People experiencing cardiac arrest will suddenly become unresponsive and either stop breathing or gasp for air, a sign known as agonal breathing. Immediate CPR can double or triple someone’s chance of survival, but that requires a bystander to be present.

More than half of patients with relapsed multiple myeloma treated with carfilzomib experienced cardiac issues during treatment, according to a multi-institutional study published June 12 in Journal of Clinical Oncology. The study recommends that patients undergo a detailed cardiovascular history before being prescribed carfilzomib and then be monitored with natriuretic peptide testing, an indicator for

Various clinical trials indicate what effects can be expected from standardized intervention programs on the basis of existing evidence. Little is known about the way in which such programs can be implemented in actual care practice. However, it may be possible to use data from clinical practice to estimate the potential of drug prescriptions to

Mystery of the energy of the heart, solved Our heart always holds many secrets. How does the body to supply every cell of our body with energy? The answer to this question recently delivered a German research team. They discovered a previously unknown group of Mini-proteins, the heart uses to produce energy. The revolutionary discovery

Mystery of the energy of the heart, solved Our heart always holds many secrets. How does the body to supply every cell of our body with energy? The answer to this question recently delivered a German research team. They discovered a previously unknown group of Mini-proteins, the heart uses to produce energy. The revolutionary discovery

Better than drugs: DASH diet protects against heart disease A nutrition study, which was accompanied by 4,500 people over 13 years, proves that a certain diet can reduce the risk for heart disease dramatically. In particular, persons under 75 years were able to benefit from the so-called DASH diet, the extra is designed to reduce

Researchers at the Fralin Biomedical Research Institute at Virginia Tech Carilion have revealed how a genetic message to produce healthy heart tissue is altered in the body during stress and aging to contribute to sudden cardiac death. The discovery published in today’s (Tuesday, May 28) Cell Reports centers on communication between heart cells and allows

A simple innovation the size of a grain of sand means we can now analyse cells and tiny particles as if they were inside the human body. The new micro-device for fluid analysis will enable more tailored experiments in drug development and disease research via new ‘organ-on-chip’ systems. It could also transform water contamination testing