Tag: how

How transcription factors work together in cancer formation

A new study co-authored by University of Colorado Cancer Center researcher Srinivas Ramachandran, Ph.D., shows how DNA segments known as enhancers function in cells. The paper published last month in Molecular Cell highlighted the work from Ramachandran, along with Satyanarayan Rao, both part of the Department of Biochemistry and Molecular Genetics at the CU School

Researchers describe how embryonic stem cells keep optimal conditions for use in regenerative medicine

Scientists at the Proteomics Core Unit of the Spanish National Cancer Research Centre (CNIO), headed by Javier Muñoz, have described the mechanisms, unknown to date, involved in maintaining embryonic stem cells in the best possible state for their use in regenerative medicine. Their results, published in Nature Communications, will help to find novel stem-cell therapies

How does COVID-19 affect the heart?

A year into the COVID-19 pandemic, doctors and researchers are beginning to understand how the disease affects patients beyond initial respiratory symptoms. Mariam Bonyadi Camacho, a student in the medical scholars program at the University of Illinois Urbana-Champaign, co-wrote a recent report on the coronavirus’ cardiac effects, both short- and long-term. In an interview with

How AstraZeneca’s errors eroded US confidence in its COVID shot

The United States was among the biggest backers of the AstraZeneca COVID vaccine, but a series of blunders by the company eroded American authorities’ confidence and have delayed rollout in the world’s hardest-hit country. The British-Swedish drugmaker was on the backfoot Tuesday, vowing to release more data “within 48 hours” after the US National Institute

How specialist palliative care services around the world coped in response to COVID-19

Specialist palliative care services have been flexible, highly adaptive and have embraced a low-cost “frugal innovation” model in response to the COVID-19 pandemic say researchers. The CovPall study, published in Palliative Medicine, is a collaborative project between Lancaster University, Cicely Saunders Institute at King’s College London, Hull York Medical School and the University of York.

How oral health may affect your heart, brain and risk of death

Dental cavities could significantly increase the risk of a life-threatening stroke from bleeding in the brain, according to new research. Past studies have shown a link between gum infection and stroke, but few studies have looked into what role dental cavities might play. In the new study, researchers looked specifically at cavities and intracerebral stroke,

How Losing 260 Pounds Quite Literally Saved My Life

Neal Bendesky, a.k.a. the 199 Guy, tells Men’s Health how working out with Orangetheory Fitness and committing to good nutrition have given him a new—and longer—lease of life. I used to be a prisoner of my job as a senior sports marketing and sales executive for major professional and college teams. I had exciting, high-profile

Research shows how mutations in SARS-CoV-2 allow the virus to dodge immune defenses

The vast majority of people infected with SARS-CoV-2 clear the virus, but those with compromised immunity—such as individuals receiving immune-suppressive drugs for autoimmune diseases—can become chronically infected. As a result, their weakened immune defenses continue to attack the virus without being able to eradicate it fully. This physiological tug-of-war between human host and pathogen offers

How a receptor shapes the immune response

Researchers led by Professor Carolyn King of the University of Basel have developed a method to study the specialization of T cells in the context of infections. In the journal eLife, they report the different directions this specialization takes, depending on whether it happens in the context of an acute viral infection such as influenza

How moving the homeless to hotels during the pandemic helps everyone

(HealthDay)—Giving homeless COVID-19 patients a free hotel room for their quarantine and recovery pays huge health dividends for the entire community, according to a new study out of San Francisco. Only 4% of homeless folks transferred from Zuckerberg San Francisco General Hospital to a participating hotel wound up back in the hospital with worsened COVID-19

Working from home? Here’s how to preserve your posture

If you’re working at home during the COVID-19 pandemic, you need to have a work space that’s doesn’t cause pain or discomfort in your back, neck or legs, a spine specialist says. “Most couches may not provide the same type of support and contour as an ergonomic office chair, so your back and neck may

A new theory for how memories are stored in the brain

Research from the University of Kent has led to the development of the MeshCODE theory, a revolutionary new theory for understanding brain and memory function. This discovery may be the beginning of a new understanding of brain function and in treating brain diseases such as Alzheimer’s. In a paper published by Frontiers in Molecular Neuroscience,