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Recruitment of miR-8080 by luteolin inhibits AR-V7 in castration-resistant prostate cancer

Prostate cancer is the most common noncutaneous malignancy in the United States and is responsible for many male deaths. The development of prostate carcinogenesis is initially androgen-dependent. However, the progression of castration-resistant prostate cancer (CRPC) following androgen deprivation therapy is a major clinical problem. Although enzalutamide and abiraterone have been approved for CRPC hormone therapy,

How much will we eat in the future?

The amount of food needed to feed the world’s population in the future is of vital importance. To date, scientists have only considered this question from the perspective of how much food people can afford to buy, how much food is healthy or what can be sustainably produced. However, researchers at the University of Göttingen

Diabetes in mothers raises risk of children having heart disease

Mothers-to-be with diabetes ‘face a greater risk of their children getting heart disease’  Scientists followed 2.4million children born in Denmark for 40 years Rates of early onset heart disease rose by 29% in people with diabetic mothers High glucose level has major implications for the development of a baby’s heart Mothers-to-be with diabetes may put

Distress tolerance plays role in alcohol use and abuse among firefighters

New findings by a University of Houston psychology professor indicate that among firefighters, distress tolerance amplifies associations between posttraumatic stress disorder (PTSD) symptoms and alcohol use severity. In the world of psychology, distress tolerance is your actual or perceived ability to withstand emotional distress. It is surviving—and knowing you can survive—an emotional incident. “Firefighters who

Holding intubated infants in ICU found to be safe, beneficial

(HealthDay)—Holding intubated infants in the intensive care unit is well tolerated and does not increase adverse events, according to a study published in the December issue of Critical Care Nurse. Laura Ortmann, M.D., and Anne Dey, D.N.P., R.N., from the Children’s Hospital and Medical Center Omaha in Nebraska, examined the safety of a holding intervention

Using machine learning tools to reveal how memories are coded in the brain

Researchers working in The N.1 Institute for Health at NUS, led by Assistant Professor Camilo Libedinsky from NUS Psychology, and Senior Lecturer Shih-Cheng Yen from the Innovation and Design Programme at NUS Engineering, have discovered that a population of neurons in the brain’s frontal lobe contain stable short-term memory information within dynamically-changing neural activity. This

Study explores new tracer in prostate cancer hunt

A new study looks to move doctors and patients closer to earlier and more precise detection of recurrent prostate cancer that would clarify treatment decisions and lead to more confident courses of action and better health outcomes. A multi-center trial registry testing the use of a new imaging tracer—prostate specific membrane antigen (PSMA) – is