Tag: lung

Woman, 68, receives her lung donor’s peanut allergy

Woman, 68, who received a lung transplant develops her donor’s peanut allergy in ‘very rare’ phenomenon The unnamed patient, from San Diego, had never had a reaction to nuts before When doctors heard a sandwich triggered her symptoms they were suspicious Nut allergies are only believed to have been passed on four or five times

Potential therapeutic target for lung fibrosis identified

In an article published online by Frontiers in Endocrinology, researchers at the Medical University of South Carolina (MUSC) report that they have identified a potential therapeutic target for lung fibrosis or scarring. They showed in a preclinical model that the protein promotes fibrosis by turning on profibrotic genes and increasing levels of profibrotic factors, including

Lung transplant patients face elevated lung cancer risk

In an American Journal of Transplantation study, lung cancer risk was increased after lung transplantation, especially in the native (non-transplanted) lung of single lung transplant recipients. This was a large registry-linkage study that utilized matched transplant and cancer registry data from 17 US states/regions, including approximately 50 percent of US transplant recipients from 1987-2012. Researchers

Team spots clue to rare lung and kidney diseases

Pulmonary-renal syndrome (PRS) refers to a group of rare but potentially fatal conditions that nearly always are caused by a misguided attack by the body’s immune system on the lungs and kidneys. Coughing up blood and blood in the urine are telltale signs. Treatment with corticosteroids and immunosuppressant drugs can be effective if begun before

Most patients with cystic fibrosis may receive insufficient antibiotics to fight lung infections

The majority of patients with cystic fibrosis may not achieve blood concentrations of antibiotics sufficiently high enough to effectively fight bacteria responsible for pulmonary exacerbations, leading to worsening pulmonary function, indicates a study led by researchers at Children’s National Health System. Additionally, the study findings show that it’s impossible to predict solely from dosing regimens

Childhood risk profiles affect middle-age lung function

(HealthDay)—Profiles of childhood respiratory risk factors predict middle-age lung function levels and chronic obstructive pulmonary disease (COPD) risk, according to a study published in the September issue of the Annals of the American Thoracic Society. Dinh S. Bui, from the University of Melbourne in Australia, and colleagues assessed 11 childhood risk factor profiles (documented at

Lung inflammation from childhood asthma linked with later anxiety

Persistent lung inflammation may be one possible explanation for why having asthma during childhood increases your risk for developing anxiety later in life, according to Penn State researchers. In a study with mice, researchers found that childhood exposure to allergens was linked with persistent lung inflammation. It was also connected to changes in gene expression

Poor Shared Decision-Making for Lung Cancer Screening

TUESDAY, Aug. 28, 2018 — The quality of shared decision-making (SDM) about the initiation of lung cancer screening (LCS) is poor, according to a study published online Aug. 13 in JAMA Internal Medicine. Alison T. Brenner, Ph.D., M.P.H., from the University of North Carolina at Chapel Hill, and colleagues conducted a qualitative content analysis of

Study shows biomarker panel boosts lung cancer risk assessment for smokers

A four-protein biomarker blood test improves lung cancer risk assessment over existing guidelines that rely solely upon smoking history, capturing risk for people who have ever smoked, not only for heavy smokers, an international research team reports in JAMA Oncology. “This simple blood test demonstrates the potential of biomarker-based risk assessment to improve eligibility criteria

Oxygen therapy could help combat dementia in individuals with lung disease

Breathing in additional oxygen improves the function of blood vessels in the brain of people with breathing difficulties caused by lung conditions, according to new research published in Experimental Physiology. These findings could have implications for future research aiming to prevent the development of diseases affecting the brain, such as dementia. Chronic obstructive pulmonary disease

Low vitamin D levels associated with scarring lung disease

Reviewing medical information gathered on more than 6,000 adults over a 10-year period, Johns Hopkins researchers have found that lower than normal blood levels of vitamin D were linked to increased risk of early signs of interstitial lung disease (ILD). Interstitial lung disease is a relatively rare group of disorders characterized by lung scarring and

Blood test shows potential for early detection of lung cancer

A test that analyzes free-floating DNA in the blood may be able to detect early-stage lung cancer, a preliminary report from the ongoing Circulating Cell-Free Genome Atlas (CCGA) study suggests. The findings, from one of the first studies to explore whether sequencing blood-borne DNA is a feasible approach to the early cancer detection, will be