Tag: Neurons

Neurons that fire together, don’t always wire together

As the adage goes “neurons that fire together, wire together,” but a new paper published today in Neuron demonstrates that, in addition to response similarity, projection target also constrains local connectivity. Researchers from the Sainsbury Wellcome Centre have been looking to elucidate the rules of connectivity of neurons in the neocortex with the long term

Watching neurons in action

Capturing the activity of neurons in the form of electric impulses isn’t easy. Information processing happens on different time scales and involves quick changes in voltage, ion concentrations and multiple signaling molecules. In a new study published in the journal Nature Communications, scientists from the Optical Neuroimaging Unit at the Okinawa Institute of Science and

New technique helps uncover changes in ALS neurons

Northwestern Medicine scientists have discovered that some neurons affected by amyotrophic lateral sclerosis (ALS) display hypo-excitability, using a new method to measure electrical activity in cells, according to a study published in Stem Cell Reports. “The excitability changes observed in these patient neurons most likely represent the early steps in the disease process,” said Evangelos

Lab-grown neurons improve breathing in mice after spinal cord injury

Researchers from Drexel University College of Medicine and the University of Texas at Austin improved respiratory function in rodents with spinal cord injuries after successfully transplanting a special class of neural cells, called V2a interneurons. Their results, published this week in the Journal of Neurotrauma, indicate that these lab-grown cells have the potential to one

Researchers transform human blood cells into functional neurons

Human immune cells in blood can be converted directly into functional neurons in the laboratory in about three weeks with the addition of just four proteins, researchers at the Stanford University School of Medicine have found. The dramatic transformation does not require the cells to first enter a state called pluripotency but instead occurs through

The joy of neurons: A simplified ‘cookbook’ for engineering brain cells to study disease

Scientists at The Scripps Research Institute have devised what they call a “neuronal cookbook” for turning skin cells into different types of neurons. As reported today in the journal Nature, the research opens the door to studying common brain conditions such as autism, schizophrenia, addiction and Alzheimer’s disease under reproducible conditions in a dish. “The