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The cover for issue 54 of Oncotarget features Figure 2, “Comparative proteomic profiling of the peptides/proteins identified from 293T, IL16lamp2b and mExo-Tat samples,” by Lu, et al. The HIV-1 Tat protein is a potent activator of viral transcription. The researcher’s previous work has demonstrated that exosomal formulations of Tat can reverse HIV-1 latency in primary

Transgender people who are also racial and ethnic minorities have a difficult time finding a healthcare setting where all aspects of their identity are welcome, understood and addressed. In a new study published in the October issue of the Journal of General Internal Medicine, a research team from the University of Chicago Medicine shows how

Government BANS drug wholesalers from exporting 24 medications including HRT pills amid nationwide shortage Government imposed ban last night on export of HRT drugs, epipens and more UK pharmaceuticals are not able to sell their product abroad for higher price  Follows pharmacists’ warning they are ‘barely coping’ trying to source medicine  Drug wholesalers have been

New research from King’s College London has found that a diet low in fermented carbohydrates has improved certain gut symptoms and improved health-related quality of life for sufferers of inflammatory bowel disease (IBD). In a paper published today in Gastroenterology a team of researchers carried out a trial of a diet low in fermentable oligosaccharides,

Researchers at the University of Bergen in Norway have identified new genetic signals for the regulation of how infants grow. This may be a crucial step in the fight against growth-related diseases. “A better understanding of the biology of infant growth is important as growth-related diseases such as obesity and malnutrition are global societal challenges,”

Breastfed babies may face more than DOUBLE the risk of developing food allergies ‘because of their delayed introduction to potential triggers’ Japanese scientists analysed how more than 46,000 infants were fed Exclusively breastfed babies were more than twice as at risk, the study found Infants may develop allergies if they are not exposed to foods

Artificial blood made in the laboratory could be transfused into ANY patient – regardless of their blood type, claim scientists When tested on 10 rabbits with severe blood loss, six of them survived This is reportedly comparable to if the animals were treated with real blood  Patients currently have to go to hospital where doctors

Revolting moment a diabetic patient with a gaping HOLE in their foot gets it patched up as podiatrist scrapes at the wound to clear away the dead skin Dr Todd Brennan, 35, treated the patient at Healthy Feet Podiatry clinic in Florida Patient had developed an ulcer which became infected without them knowing  Because diabetics have

Nintedanib, a medication approved for the treatment of idiopathic pulmonary fibrosis, slows the decline in lung function among patients with a broad range of scarring lung diseases. The findings, published in the New England Journal of Medicine, suggest that many more people may benefit from nintedanib than are currently approved for treatment. They also suggest

Professional drivers working in congested cities are exposed to black carbon levels that are on average a third higher than would be experienced at a busy roadside, according to research presented at the European Respiratory Society International Congress. The research also found that taxi drivers experience the highest exposures to black carbon, an indicator of

In the largest smoking cessation study of cancer patients to date, researchers from The University of Texas MD Anderson Cancer Center found that comprehensive tobacco treatment can help cancer patients successfully quit and abstain from smoking. The prospective study, published today in JAMA Network Open, analyzed 3,245 smokers treated in MD Anderson’s Tobacco Treatment Program

TWELVE Americans have died of vaping-linked illness and 805 have severe lung damage, CDC reports Vaping-related illnesses have claimed the lives of 12 Americans, the Centers for Disease Control and Prevention said on Thursday.  The total number of confirmed or probable cases across the country is creeping toward 1,000, at 805.  Deaths have occurred in

Non-alcoholic fatty liver disease prevalence in Europe is a preventable epidemic, leading researchers will report at the EASL Non-Alcoholic Fatty Liver Disease (NAFLD) Summit 2019 taking place this week in Seville, Spain. More than half of adults and one third of children in Europe are classified as overweight or obese, with the highest proportion coming

Light brown skin speckles on Oklahoma girl, 4, turn out to be a warning sign of a brain tumor Charlie Thomas, four, from Moore, Oklahoma, was born with light-brown spots all over her body Her parents were told they were birth marks, but weren’t convinced and ordered a number of tests Doctors preformed an MRI,

It’s a problem many teachers are familiar with, a student apparently struggling in class, but in fact just suffering from something that’s easily fixed—vision problems—with an inexpensive pair of glasses. It’s estimated that more than 3.4m children aged four to 16 in the UK have been diagnosed with a vision problem. Indeed, vision screenings are

Research published today in the journal Circulation has found that women with high blood pressure in pregnancy, including conditions such as preeclampsia, have an increased risk of developing cardiovascular disorders later in life, including stroke and heart failure. Led by King’s College London, the team of researchers studied electronic health records from 1997 to 2016

Experts agree that the first three years of a baby’s life are a unique time of fast development. Even though a newborn seems helpless, he or she is learning every minute, absorbing information through all five senses. That’s why babies will try to put everything possible in their mouths. It’s a way of understanding as

The World Health Organization (WHO) recently declared vaccine hesitancy one of the ten biggest threats to global health in 2019, along with air pollution and climate change. The declaration followed several measles outbreaks in Europe and the US, but most cases were in a country where the health system had broken down: Ukraine. Nothing suggests

Breastfed children have a lower risk of obesity, which may be linked to reduced expression of the hormone, leptin; according to research presented today at the 58th Annual European Society for Paediatric Endocrinology Meeting. The study reported that genetic modifications known to suppress leptin levels were more common in breastfed babies than formula-fed, and that

When immune cells detect harmful pathogens or cancer, they mobilise and coordinate a competent defence response. To do this effectively immune cells must communicate in a way that is tailored to the pathogenic insult. Consequently, the body’s response to various health challenges depends on successful coordination among the cells of the immune system. Key players