Tag: Researchers

Researchers from the Mitochondrial Medicine Frontier Program at Children’s Hospital of Philadelphia (CHOP) have demonstrated how one combination of therapies may be beneficial for patients with mitochondrial respiratory chain disorders. This preclinical research paves the way to develop more tailored treatment options for patients with inherited mitochondrial disease and acquired energy disorders. The findings emphasize

Yellow fever was the first human disease to have a licensed vaccine and has long been considered important to understanding how epidemics break out and should be combated. It was introduced to the Americas in the 17th century, and high death rates have resulted from successive outbreaks since then. Epidemics of yellow fever were associated

The COVID-19 vaccine has arrived and currently, priority populations are at the top of the list to receive inoculations. Seniors over 65, individuals with underlying health conditions, healthcare workers and essential frontline workers are those who will be the first to receive vaccinations. Among the frontline workers not included in this first inoculation group are

Researchers from Indiana University have identified key genetic changes in the interstitial kidney tissue of people with diabetes, a discovery that signifies the potential for a revolutionary new genetic approach to the treatment of kidney disease. They will contribute their findings to the Kidney Precision Medicine Project’s (KPMP) “cell atlas,” a set of maps used

It does not happen often. But on rare occasions, physicians make mistakes and may make a wrong diagnosis. Patients may have many diseases all at once, where it can be difficult to distinguish the symptoms of one illness from the other, or there may be a lack of symptoms. Errors in diagnosis may lead to

A research team led by the Icahn School of Medicine at Mount Sinai (Icahn Mount Sinai) has built the first cellular model to depict the evolution of acute myeloid leukemia (AML), from its early to late stages. By using gene editing technologies to alter genes that make cells malignant, the team was able to identify

Shortages of many essential drugs amid the COVID-19 crisis reveal serious vulnerabilities in the systems for supplying and distributing pharmaceuticals in the United States, according to a new report led by researchers at the Johns Hopkins Bloomberg School of Public Health. In the report, “The Pandemic and the Supply Chain,” the researchers identify multiple problems

Shortages of many essential drugs amid the COVID-19 crisis reveal serious vulnerabilities in the systems for supplying and distributing pharmaceuticals in the United States, according to a new report led by researchers at the Johns Hopkins Bloomberg School of Public Health. In the report, “The Pandemic and the Supply Chain,” the researchers identify multiple problems

A test that detects antibodies to the novel coronavirus in 10 minutes and costs only a fifth of the market average has been developed by researchers at the University of São Paulo’s São Carlos Chemistry Institute (IQSC-USP) and Brazilian startup Biolinker, with São Paulo Research Foundation—FAPESP’s support. The device works similarly to the rapid tests

As President Joe Biden promises to vaccinate more than 100 million Americans by the end of his first 100 days in office (April 29), new research offers several critical insights for those in charge of managing such a massive national public health effort. The researchers, who hail from four major U.S. universities, including Northwestern University,

The COVID-19 pandemic has significantly impacted dental education and training. The study “COVID-19 and Dental and Dental Hygiene Students’ Career Plans,” published in the JDR Clinical & Translational Research (JDR CTR), examined the short-term impact of the COVID-19 pandemic on dental hygiene and dental students’ career intentions. An anonymous online survey was emailed to dental

Another day, another announcement about a COVID-19 vaccine. Whether that’s talk of results from clinical trials, emergency approval or plans for countries to prioritize certain groups for vaccination. But we still don’t know if current vaccines prevent disease and also prevent people transmitting the virus to others. This not only has implications for vaccines we’ve

University of California, Irvine health sciences researchers have created a machine-learning model to predict the probability that a COVID-19 patient will need a ventilator or ICU care. The tool is free and available online for any healthcare organization to use. “The goal is to give an earlier alert to clinicians to identify patients who may

People with serious mental illness should be given priority access to a COVID-19 vaccine when one becomes available, say University of Queensland researchers. Studies show people with serious mental illness are more likely to be infected by the COVID-19 virus and have higher rates of hospitalization due to medications, poorer general health, reduced access to

Scientists from Johns Hopkins University and Medicine have developed a possible new antibiotic for a pathogen that is notoriously resistant to medications and frequently lethal for people with cystic fibrosis and other lung ailments. The pathogen, called Mycobacterium abscessus, is related to a better-known bacterium that causes tuberculosis and leprosy but has recently emerged as

Researchers from the University of Missouri School of Medicine have discovered a treatment combination that significantly reduces tumor growth and extends the life span of mice with liver cancer. This discovery provides a potentially new therapeutic approach to treating one of the leading causes of cancer-related death worldwide. A cancer translational research team consisting of

A study led by researchers at the National Institutes of Health has made a surprising connection between frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), two disorders of the nervous system, and the genetic mutation normally understood to cause Huntington’s disease. This large, international project, which included a collaboration between the National Institute of Neurological

Recently, a research team led by Profs. Liu Qingsong and Liu Jing from the Institute of Health & Medical Technology of the Hefei Institutes of Physical Science (HFIPS) discovered a potent and selective PI3Kδ inhibitor IHMT-PI3Kδ-372, effective against chronic obstructive pulmonary disease (COPD) in vivo. COPD is a chronic progressive respiratory disease characterized by airflow

Doctors need to keep a close eye on babies that are born prematurely, and brain oxygenation is perhaps the most important thing to monitor. Up to 50 percent of premature babies suffer brain damage, leading to neurological problems. Researchers at Delft University of Technology have now developed a wireless sensor that monitors the health of

When antibody-producing immune cells encounter infectious pathogens for the first time, they engage a signal cascade to generate a massive activation signal within seconds. The mechanisms underlying this acute initial activation have not been fully understood. In a new study by Yale Cancer Center, scientists have identified the short endosomal protein interferon-inducible transmembrane protein 3