Tag: Researchers

A team of researchers affiliated with several institutions in China and one in the U.S. has found that people with schizophrenia have differences in their gut biomes compared to people without the mental disorder. In their paper published in the journal Science Advances, the group describes testing schizophrenia patients and experiments they conducted with mice,

Like cartographers completing a map, investigators have identified multiple new subtypes of the most common childhood cancer—research that will likely improve the diagnosis and treatment of high-risk patients. St. Jude Children’s Research Hospital scientists led the study, which appears as an advance online publication today in the journal Nature Genetics. Researchers used integrated genomic analysis,

Schizophrenia, a condition characterized by a confused perception of reality, delusions, and altered behavior, affects more than 21 million people globally. In a new study, specialists from Johns Hopkins Medicine in Baltimore, MD, and the Sheppard Pratt Health System in Townson, MD, found evidence that links schizophrenia with the Epstein-Barr virus. This is a herpes

Credit: CC0 Public Domain University of Minnesota Medical School researchers decided to delve into an area where little data currently exists. They wanted to know what happens after these patients with abnormal blood glucose measurements are discharged? Are uncontrolled blood glucose levels associated with worse outcomes after patients are discharged from the hospital? Surprisingly, despite

USC researchers seeking a way to study genetic activity associated with psychiatric disorders have discovered an abundant source of human cells—the nose. Olfactory epithelial cells, easily collected from the lining of the nasal cavity, can serve as stand-ins for brain cells in studies of the neuronal epigenome, USC researchers say. The epigenome is a system

In the ongoing hunt for more effective weapons against malaria, international researchers said Thursday they are exploring a pathway that has until now been little studied—killing parasites in the liver, before the illness emerges. “It’s very difficult to work on the liver stage,” said Elizabeth Winzeler, professor of pharmacology and drug discovery at University of

UC San Francisco scientists have figured out why some lung cancers become drug-resistant after initially responding to targeted therapies. In the process, they devised a new two-pronged approach that yields an effective treatment for these cancers in the laboratory and holds tremendous promise for the future of precision medicine, they said. The findings are detailed

Genetics can be used to predict a patient’s response to antipsychotic drug treatment for schizophrenia, according to a recent study by investigators at The Feinstein Institute for Medical Research. The findings were published online today in the American Journal of Psychiatry. Schizophrenia is one of the leading causes of disability in the U.S. It is

Washington State University researchers have seen cognitive changes in the offspring of rats exposed to heavy amounts of cannabis. Their work is one of the rare studies to look at the effects of cannabis during pregnancy. The drug is the most commonly used illicit substance among pregnant women. Ryan McLaughlin, an assistant professor of Integrative

WWII codebreaker Alan Turing’s mathematical genius could create better detection tests for cancer and other fatal diseases, experts say Turing’s ‘weight of evidence’ theory may assist in better diagnostic tools  It could also personalise treatment to maximise a person’s chances of recovery Currently, modern-day testing relies on techniques developed in the mid 1980s  Alan Turing’s

Scorpions can be found at every corner of the globe and on six of the seven continents, from the southern tip of South America to the arid expanse of the Sahara Desert. That makes any rigorous accounting of the world’s venomous scorpions—and their various effects on human beings—an extremely tall task. But in a new

Two decades ago, Clifford B. Saper, MD/Ph.D., Chairman of the Department of Neurology at Beth Israel Deaconess Medical Center (BIDMC), and colleagues discovered a set of nerve cells they thought might be the switch that turns the brain off, allowing it to sleep. In a new study published in Nature Communications today, Saper and colleagues

Researchers at Mayo Clinic have developed a new genetics-based prognostic tool for myelodysplastic syndrome. Their findings are published in the October print issue of Mayo Clinic Proceedings. “Myelodysplastic syndrome is one of the most frequent blood cancers affecting the elderly with annual incidence exceeding 50 cases per 100,000 in people 65 years or older,” says

Imagine a situation where one child is teasing another. While the child doing the teasing means it playfully, the other child views it as hostile and responds aggressively. Behavior like this happens all the time with children, but why some react neutrally and others act aggressively is a mystery. In a new study, a University

Concussion symptoms for children under 13 years old typically last three times longer than they do for older teens and adults, but keeping them out of the classroom during recovery is not necessarily the preferred treatment, according to a comprehensive research review in The Journal of the American Osteopathic Association. Parents should be aware that

Researchers at the Kavli Institute for Systems Neuroscience in Norway have discovered a network of brain cells that expresses our sense of time within experiences and memories. “This network provides timestamps for events and keeps track of the order of events within an experience,” says Professor Edvard Moser, Nobel laureate and director of the Kavli

Researchers at the University of Florida have discovered that a modified version of an important immune cell protein could be used to treat Alzheimer’s disease. The study, which will be published August 29 in the Journal of Experimental Medicine, reveals that soluble versions of a protein called TLR5 can reduce the buildup of amyloid plaques

In a study published today in Science, UT Southwestern and Rockefeller University researchers used advanced microscopes to determine at atomic resolution the structure of a molecular complex implicated in birth defects and several cancers. The Hedgehog signaling pathway, which transmits information to embryonic cells, is crucial to human health. Insufficient signaling during development leads to

Keratinocyte skin cells are common targets of the beta subtype of human papilloma virus. This usually harmless infection causes skin disease in people with rare gene mutations.[/caption] You’re probably infected with one or more subtypes of the human papilloma virus—and, as alarming as that may sound, odds are you will never show any symptoms. The

A new study published in Molecular Genetics and Metabolism, conducted by a Liverpool based research collaboration involving the University of Liverpool, has identified the drug that treats the extremely rare genetic disease alkaptonuria (AKU). An observational study at the NHS-funded Robert Gregory National Alkaptonuria Centre (NAC), based at the Royal Liverpool University Hospital, in collaboration