Tag: Rodents

Too much vitamin A may increase risk of bone fractures

Consuming too much vitamin A may decrease bone thickness, leading to weak and fracture prone bones, according to a study published in the Journal of Endocrinology. The study, undertaken in mice, found that sustained intake of vitamin A, at levels equivalent to 4.5-13 times the human recommended daily allowance (RDA), caused significant weakening of the

Scientists uncover brain circuits behind putting up a fight or freezing in place: Study may provide clues to disorders including anxiety and phobias

In a study of mice, National Institutes of Health-funded researchers describe a new circuit involved in fine-tuning the brain’s decision either to hide or confront threats. The study, published in Nature, was partially funded by the NIH’s Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative. “Being able to manipulate specific circuits can uncover surprising relationships

Eating less enables lemurs to live longer

Chronic caloric restriction consists in eating a reduced but balanced diet from early adult life onward. Previous research, into macaques in particular (which have an average lifespan of forty years), had already demonstrated its beneficial effect on the incidence of age-related pathologies. However, its positive effect on the lifespan of primates remained controversial. To study