Tag: signaling

Missing component of innate immune signaling identified

How cells recognize pathogens and alert the immune system swiftly is a fundamental process of high importance for the survival of any species, including humans. A key role is ascribed to so-called adapters—little molecular platforms inside cells where signals from pathogen detectors are integrated for safety and accuracy and conveyed to lasting signals leading to

Flip a switch and shut down seizures? New research suggests how to turn off out-of-control signaling in the brain

The brain is a precision instrument. Its function depends on finely calibrated electrical activity triggering the release of chemical messages between neurons. But sometimes the brain’s careful balance is knocked out of control, as in epilepsy. Electroencephalography, or EEG, visualizes a brain’s electrical activity and can reveal how an epileptic seizure diverges from the predictable