The annual cost of chronic pain in the United States is estimated to be more than $635 billion in direct medical costs, lost productivity and disability programs. One in five adults—50 million Americans—report living in chronic pain. The increasing number of patients is leading to a major push to develop non-opioid treatments for chronic pain.
Pinpointing how different emotional states and neural pathways influence our eating behaviours could pave the way for better ways to tackle eating disorders and obesity. Eating disorders such as anorexia and bulimia can have life-threatening consequences. They affect around 20 million people in the European Union, with an estimated cost of €1 trillion per year.
A comprehensive new review of the expanding scope of stimulants available to treat attention deficit hyperactivity disorder (ADHD) serves as a valuable guide to clinicians as they choose from among the many new drug formulations and technologies available to treat this complex disorder. The wide-ranging review is published in the Journal of Child and Adolescent
A new drug that inhibits neonatal seizures in rodent models could open up new avenues for the treatment of epilepsy in human newborns. Researchers have identified that gluconate—a small organic compound found in fruit and honey—acts as an anticonvulsant, inhibiting seizures by targeting the activity of channels that control the flow of chloride ions in
Drugs used to target HER2-positive invasive breast cancer may also be successful in treating women in the first stages of the disease, researchers at The University of Nottingham have discovered. The findings, published in the British Journal of Cancer and led by experts in the University’s School of Medicine, suggest that extending anti-HER2 drugs to
Ask a parent — any parent — how they manage technology and kids’ screen time in their household, and you’ll hear a range of philosophies. And that’s because there’s no one-size-fits-all answer. “It’s easy to focus on the risks and limitations,” Polly Palumbo, psychologist and founder of MommaData, tells SheKnows. In that regard, she says
Diagnosing autism can take half a day or more of clinical observation, and that’s the quick part – often, families wait years just to get to that point. Now, in hopes of speeding things up, Stanford researchers are developing a smartphone app that could drastically reduce the time it takes to get a diagnosis. The
Understanding and mitigating the role of epigenetics (environmental influences that trigger changes in gene expression) in disease development is a major goal of researchers. Now, a newly published paper featured on the March cover of the journal Brain adds significantly to this work by detailing how metabolites can be used to inhibit epigenetic mechanisms and
Controversial electric shock therapy approved on the NHS to treat depression is not safe and should be stopped, leading researcher argues Electroconvulsive or ‘shock’ therapy induces seizures to treat mental illnesses Professor John Read said its use is based on positive studies as old as 30 years It can cause memory loss and has been badly
January 2, 2019—As early as 3 months of age, infants with a severe form of epilepsy called Dravet syndrome start having convulsive seizures, during which their arms and legs jerk repeatedly. As they become toddlers, another type of seizure begins to appear. These seizures do not cause obvious convulsions, but disrupt consciousness and can occur
We don’t know about you, but we really love oatmeal. It makes for a cozy five-minute breakfast in winter months, and cold overnight oats are easy and refreshing in the summer (although, TBH, we mostly stick to hot oats all year). And we still can’t get over the fact that something so easy and inexpensive
Hope of a Parkinson’s breakthrough as experts transplant MILLIONS of stem cells into a patient’s brain ‘to regrow parts ravaged by the disease’ Experts at Kyoto University in Japan performed the first-of-its-kind procedure The man is in his 50s and is one of seven people who will take part in the trial The procedure has
Pin Kids love Halloween — or at least the dressing up and getting candy part. But should teens or even college-age kids really be out there trick-or-treating with the little kids? Child psychologist Michele Borba tells SheKnows that while there’s no one-size strict age cutoff, most kids decide that between 12 and 17 they feel
Engineers and medical researchers at the University of Minnesota have teamed up to create a groundbreaking 3-D-printed device that could someday help patients with long-term spinal cord injuries regain some function. A 3-D-printed guide, made of silicone, serves as a platform for specialized cells that are then 3-D printed on top of it. The guide
Bile acids that aid fat digestion are also found to reduce the rewarding properties of cocaine use, according to a study publishing on July 26 in the open-access journal PLOS Biology by India Reddy, Nicholas Smith, and Robb Flynn of Vanderbilt University, Aurelio Galli of the University of Alabama at Birmingham, and colleagues. The results
Increasingly, doctors are treating lung cancer based on the genetic rearrangements driving the disease. For example, cancers that are driven by changes in the genes ALK, EGFR, and ROS1 can now all be paired with drugs that target these specific changes. However, these cancers are not only dangerous in the lung where they appear, but
Alzheimer’s disease (AD) is the most common form of dementia. It takes a devastating toll on patients and family members, who are usually the caregivers. Current drugs only treat symptoms of AD, not its causes. FIU researchers are studying a new approach to treating Alzheimer’s using nanotechnology aimed at reducing the inflammation in the brain.
The drug — which is activated by shining light down an optical fiber implanted in the brain — reduced Parkinson’s symptoms and improved motor function in mice. In a paper about the work now published in the Journal of Controlled Release, the international team suggests that the “light-operated” drug could potentially treat other movement disorders.
Researchers from the Papua New Guinea Institute for Medical Research and UNSW’s Kirby Institute say health services are needed to tackle high rates of HIV, hepatitis and STIs among key populations in PNG. Expanded health and social services are needed to urgently address HIV in Papua New Guinea, according to new research conducted by the
Patients with stroke caused by bleeding on the brain (intracerebral haemorrhage) may benefit from receiving a drug currently used to treat blood loss from major trauma and bleeding after childbirth, an international trial has revealed. The study, led by experts at The University of Nottingham and funded by the National Institute for Health Research (NIHR)