Tag: Viruses

Sustainability of plant ingredients as fishmeal substitutes

Substituting fishmeal in aquaculture feeds with plant ingredients may not be as beneficial for the environment as many predict, according to new research from an international team of experts. Manufacturers of commercial fish feed are increasingly substituting fishmeal — a powder made from fish — with crop-based ingredients in a move driven by economic incentives

Hurricane Maria had a significant impact on HIV care outcomes

Hurricane Maria in San Juan, Puerto Rico had a significant impact on HIV outcomes among people living with HIV and a history of substance use, particularly increased viral load and decreased CD4 counts, according to early data just released by Columbia University Mailman School of Public Health, University of Puerto Rico, University of Miami, Puerto

Vaccine myths: 9 facts about vaccines everyone should know

It’s a daily routine for pediatricians: Promise a lollipop or sticker to a 4-year-old child in return for giving them a shot. Then, watch as they melt down and their parents chase them around the clinic. Even if the child doesn’t want it, the aforementioned scenario is not usually one that stops parents from vaccinating

Progress against hepatitis C by 2030 is possible

A comprehensive package of prevention, screening, and treatment interventions could avert 15.1 million new hepatitis C infections and 1.5 million cirrhosis and liver cancer deaths globally by 2030 — equal to an 80% reduction in incidence and a 60% reduction in deaths compared with 2015, according to the first study to model hepatitis C interventions

What to know about ‘tree man’ syndrome

For years, 28-year-old Abul Bajandar, from Bangaldesh, was covered with what looked like bark. His hands and feet grew foot-long, gnarled “roots,” skin lesions that left him unable to feed himself, move around, work, or wear standard clothing. A few years ago, surgery finally changed his life. But after more than 25 invasive surgeries to

Herpes viruses and tumors evolved to learn how to manipulate the same ancient RNA: Findings could have implications for drugs and insight into diseases like Alzheimer’s

Herpes viral infections use the ancient genetic material found in the human genome to proliferate, mimicking the same process tumors have been found to manipulate, Mount Sinai researchers have shown for the first time. These observations provide further insight about how herpes viruses can manipulate the immune system in ways that may drive neurodegenerative diseases

Ebola-fighting protein discovered in human cells: Drug that mimics function of protein could one day become an effective therapy to fight Ebola virus

Researchers have discovered a human protein that helps fight the Ebola virus and could one day lead to an effective therapy against the deadly disease, according to a new Northwestern Medicine study. The newly discovered ability of the human protein RBBP6 to interfere with Ebola virus replication suggests new ways to fight the infection. As

Discovery could neutralize West Nile virus

Researchers at Vanderbilt University Medical Center and colleagues have isolated a human monoclonal antibody that can “neutralize” the West Nile virus and potentially prevent a leading cause of viral encephalitis (brain inflammation) in the United States. Their findings, reported this week in the journal Nature Microbiology, could lead to the first effective treatment for this

Synthetic DNA-delivered antibodies protect against Ebola in preclinical studies

Scientists at The Wistar Institute and collaborators have successfully engineered novel DNA-encoded monoclonal antibodies (DMAbs) targeting Zaire Ebolavirus that were effective in preclinical models. Study results, published online in Cell Reports, showed that DMAbs were expressed over a wide window of time and offered complete and long-term protection against lethal virus challenges. DMAbs may also

Near-infrared spectroscopy could improve flu vaccine manufacturing

Recent research from North Carolina State University outlines how near-infrared (NIR) spectroscopy could be used to make cell-culture-based flu vaccine manufacturing faster and more efficient. The researchers demonstrated the use of a NIR probe to measure the concentration of influenza virus in cells being grown in a bioreactor. “The NIR technique is faster, more accurate

Viruses under the microscope

Human herpesvirus 6 (HHV-6) infects almost all of the human population, but only very few will show any symptoms during their lifetime: HHV-6 is one of the most widespread viruses among the population. Between 95 and 100 percent of healthy adults have antibodies to the virus which means that they have been infected at some

New technique reveals how Zika virus interacts inside our cells: Discovery could enable development of new anti-viral therapies

Scientists have developed a new technique that can determine how viruses interact with a host’s own RNA. As well as providing insight into how viruses direct the host cell to create new virus particles, this technique, published today in Nature Methods, could allow researchers to design artificial molecules capable of blocking the virus replication process

California Aedes mosquitoes capable of spreading Zika

Over the last five years, Zika virus has emerged as a significant global human health threat following outbreaks in South and Central America. Now, researchers reporting in PLOS Neglected Tropical Diseases have shown that invasive mosquitoes in California — where cases of Zika in travelers have been a regular occurrence in recent years — are

Characteristics of microorganisms most likely to cause a global pandemic

Infectious disease preparedness work focuses predominantly on an historical list of pathogens derived from biological warfare agents, political considerations, and recent outbreaks. That fails to account for the most serious agents not currently known or without historical precedent, write scholars from the Johns Hopkins Center for Health Security in a new report on the traits