A new study led by researchers at Washington State University has identified a protein that could be the key to improving treatment outcomes after a heart attack. Published in the Journal of Biological Chemistry, the research suggests that protein kinase A (PKA) plays a role in heart muscle cell necrosis, a major type of cell
A “prescription” to sit less and move more is the optimal first treatment choice for reducing mild to moderately elevated blood pressure and blood cholesterol in otherwise healthy adults, according to the new American Heart Association scientific statement published today in the American Heart Association’s journal Hypertension. “The current American Heart Association guidelines for diagnosing
It is estimated that during a heart attack, one billion cells in the heart are lost. In the wake of the heart attack, the lost tissue is replaced by scar tissue, which can lead to heart failure, arrhythmia and death. In a new study, researchers from the University of Tsukuba have shown how cells in
Parkinson's disease (PD) is a common neurodegenerative disorder caused by the death of dopaminergic neurons in a part of the brain (known as substantia nigra pars compacta), which leads to a deficit of dopamine (DA), one of the main neurotransmitters active in the central nervous system. Symptomatic treatment focuses on increasing the concentration of dopamine
A new study analyzing the association between an individual's genetics (genotype) and their observable characteristics resulting from the interaction of genetics and the environment (phenotype), contributes new knowledge to the understanding of human complex traits and diseases. The study titled, "An atlas of alternative polyadenylation quantitative trait loci (3'aQTLs) contributing to complex trait and disease
Pop quiz: In which country was the B.1.617.2 coronavirus variant first detected? If the answer (India), wasn’t on the tip of your tongue, the World Health Organization is here to help. On Monday, the WHO announced that it had a new naming system for SARS-CoV-2 “variants of concern” and “variants of interest,” meaning versions of
Aging is associated with an overall decline in health and increased frailty, and is a major risk factor for multiple chronic diseases. Frailty syndrome, characterized by weakness, fatigue and low physical activity, affects more than 30% of the elderly population. Increasing our understanding of the mechanisms underlying the aging process is a top priority to
It might seem like a given that mothers take extra risks to protect their children, but have you ever wondered why? A new study led by Kumi Kuroda at the RIKEN Center for Brain Science (CBS) in Japan shows that in mice, this and other nurturing behaviors are driven in part by neurons in a
Three years ago, oncologist Charles Canaan Williams, Jr, a lung cancer specialist and a senior member of the Thoracic Oncology Program at Moffitt Cancer Center, Tampa, Florida, was killed when an orange Dodge Charger flew through a stoplight at 95 mph and slammed into his car. The driver of the car, Igbinosa Oghubor, was subsequently
Electronic medical records (EMRs) can play an important role in the reduction of medication errors, but they should not be considered the be-all, end-all solution. Healthcare organizations, in fact, are discovering that simply implementing single-platform EMR systems is not enough to truly protect patients from the medication errors that cost the U.S. healthcare system close
The coronavirus, or rather the measurements taken against it, changed our perception of time. For many, the attempts to prevent the spread of the virus resulted in a feeling that time had come to a standstill. When the pandemic first hit, this notion of stopped time was at the core of a widespread sense of
The day Dr. Elizabeth Dawson was diagnosed with covid-19 in October, she awoke feeling as if she had a bad hangover. Four months later she tested negative for the virus, but her symptoms have only worsened. Dawson is among what one doctor called “waves and waves” of “long-haul” covid patients who remain sick long after
New research has shown that if people achieve and maintain substantial weight loss to manage their type 2 diabetes, many can also effectively control their high blood pressure and stop or cut down on their anti-hypertensive medication. A weight management programme, developed by researchers at the Universities of Glasgow and Newcastle for the Diabetes UK-funded
An emotion regulation strategy known as cognitive reappraisal helped reduce the typically heightened and habitual attention to drug-related cues and contexts in cocaine-addicted individuals, a study by Mount Sinai researchers has found. In a paper published in PNAS, the team suggested that this form of habit disruption, mediated by the prefrontal cortex (PFC) of the
By the end of 2020, COVID-19 had claimed the lives of more than three million people worldwide, representing 1.2 million more deaths than officially reported earlier, says a newly released report by the World Health Organization (WHO). The revised figures, based on excess mortality estimates produced for 2020, indicate a serious undercount of total deaths
A team of scientists from the United States has recently engineered a pre-existing anti-severe acute respiratory syndrome coronavirus (SARS-CoV) neutralizing antibody to increase its binding affinity for the spike receptor-binding domain (RBD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The engineered antibody demonstrates high potency in neutralizing SARS-CoV-2 and preventing infection in animals. Study:
In late December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, and subsequently spread rapidly across the world. On the 11th of March 2020, the World Health Organization announced the global outbreak of coronavirus disease 2019 (COVID-19) as a pandemic. Scientists around the world are working extensively to develop new vaccines,
Welcome to Stylist’s Sleep Diaries, where we’re taking a deep-dive into one of the most important (and elusive) factors in our day-to-day lives: sleep. To help us understand more about it, we’re inviting women to track their bedtime routines over a five-day period – and presenting these diaries to sleep expert Dr Nerina Ramlakhan for
The theory that COVID-19 might be the result of scientific experiments has thrown a spotlight on the work of the world’s most secure biolabs. While the evidence linking SARS-CoV-2 to the Wuhan Institute of Virology in China is strictly circumstantial, a number of experts want tougher controls on such facilities over fears that accidental leaks
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