Category: Health News

Study offers hope of new treatment for progeria syndrome in children

Researchers from Karolinska Institutet and Gothenburg University have investigated a potential new drug target for the rare genetic disorder Hutchinson-Gilford progeria syndrome that causes accelerated aging in children. The findings in mice are published in the scientific journal eLife and may aid in the development of more effective treatments for this fatal condition. Hutchinson-Gilford progeria

England to surge testing after detecting 11 S.African variant cases

Health officials said Monday they will increase testing in eight areas across England where nearly a dozen South African COVID-19 variant cases have been identified in the last week. The 11 cases, detected in genomic sequencing carried out on random samples of positive coronavirus results, cannot be traced back to international travel, prompting concerns of

Outcomes similar for younger, older teens undergoing bariatric surgery

(HealthDay)—Outcomes are similar for younger and older adolescents undergoing bariatric surgery, according to a study published online Feb. 1 in Pediatrics. Sarah B. Ogle, D.O., from the University of Colorado in Aurora, and colleagues enrolled 242 adolescents (≤19 years of age) who underwent bariatric surgery in a prospective, multicenter, long-term outcome study. Outcome data, including

DNA and Technology

DNA and molecular biology has advanced by leaps and bounds. It has found use in pharmacology, genetic engineering in disease prevention, in increasing agricultural growth, in detection of disease and crime (forensics) etc. Some fields that have shown remarkable growth due to advances in DNA technology include: forensics bioinformatics pharmacology and nanotechnology archaeology and anthropometry

Flow Cytometry Fluorescent Labels

The principle of flow cytometry is the segregation and analysis of cells which are arranged in a single line as they flow past a detector in a stream. A machine sorts and counts the cells that have been labelled or tagged using fluorescent dyes or other methods. The labels that are used depend on the

What are Nanoparticles?

A nanoparticle is a small object that behaves as a whole unit in terms of its transport and properties. Size of Nanoparticles In terms of diameter, fine particles cover a range between 100 and 2500 nanometers, while ultrafine particles are sized between 1 and 100 nanometers. Nanoparticles may or may not exhibit size-related properties that

Gene Expression System

An expression system refers to the factors that work  together to yield a particular gene product such as a protein, ribozyme or RNA particle. The expression system is made up of a gene, which is encoded by DNA, and the machinery needed to make mRNA from the DNA and translate that into a protein. In

Introduction to the Coulter Principle

The Coulter Principle is the reference method for studying particle size and dynamics, which is based on measurable variations in electrical impedance that is produced by non-conductive particles in an electrolyte solution. Today it is also used as limit test for particulate matter in parenteral solutions of large volumes. Since Coulter patented a method to

Proteomics Uses

The term proteome, coined in 1995, refers to the protein composition of the genome, while the term proteomics represents a systematic analysis of those proteins. Proteomics is used to detect protein expression patterns at a given time in response to a specific stimulus, but also to determine functional protein networks that exist at the level

Characterizing Nanoparticles

Nanoparticles are 1 – 100 nm in size and can consist of  one or a mixture of elements. Nanoparticles are commonly made up of inorganic substances such as gold, silver, or iron oxide, but can also comprise of liposomes and organic structures such as carbon nanotubes. Image Credit: Kateryna Kon / Shutterstock Nanoparticles can be

WHO team in Wuhan visits provincial disease control center

A World Health Organization team investigating the origins of the coronavirus pandemic has visited a provincial disease control center that had an early hand in managing the outbreak. The WHO investigators arrived in the Hubei provincial capital, Wuhan, last month to look for clues and have visited hospitals that treated many of the earliest patients

START and STOP Codons

The universal genetic code is made up of several codons or triplet bases. The standard code has evolved over time to minimize coding errors. There are a total of 64 codons in the genetic code arising from the permutation and combination of the 4 bases in nucleic acids. The genetic code is degenerate i.e. more

How Does CRISPR Compare to Other Gene-Editing Techniques?

Gene-editing techniques based on synthetic nucleases and transcription factors have enabled the targeted modification of gene sequence and expression. They have been used to directly targeted gene addition for therapeutic purposes, knock out genes associated with diseases and correct pathogenic mutations. Currently there are four major classes of engineered nucleases employed for genome editing purposes: