How does spironolactone work for so many conditions? When it comes to the heart, lowering blood pressure, and helping relieve edema, spironolactone works by competing with aldosterone for receptor sites in the kidneys, which increases sodium and water removal while conserving potassium. That’s why it is called a potassium-sparing diuretic. Wait, but what else? When
There are more than 200 bones in the human body. Bone is formed during embryonic and postnatal skeletogenesis by two distinct, well-organized processes, intramembranous and endochondral ossification. Mesenchymal stem cells differentiate into chondrocytes to form a cartilaginous template, which, for long bones, induces bone formation through endochondral ossification. Extracellular signal-regulated kinase 5 (Erk5), which is
A phase I clinical trial investigating the use of bacterial Clostridium novyi-NT spores as an injectable monotherapy had manageable toxicities and showed early clinical efficacy in patients with treatment-refractory solid tumor malignancies, according to data presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3. “Even after a
Lack of estrogen may play a role in the development of anxiety and memory problems, according to a new rodent study. The findings will be presented today at the American Physiological Society’s (APS) Cardiovascular, Renal and Metabolic Diseases: Sex-Specific Implications for Physiology conference in Knoxville, Tenn. Estrogen, the primary female sex hormone, regulates the female
Viagra could damage your eyes! Erection drug bought online leaves 31-year-old man with red-tinted vision (and doctors warn the damage is irreversible) The unnamed New York man took ‘much more’ than the recommended dose Doctors found his eyes were left physically damaged and couldn’t be healed The effects began shortly after the man took a
InterSystems has announced a new data and collaboration platform to enable application developers to more easily and efficiently access health data. The aim is to help healthcare organizations be more agile and effective in creating and scaling innovative apps. WHY IT MATTERS Healthcare is generating more digital data than ever before, but the enormous volume
A KAIST research team led by Professor Keon Jae Lee from the Department of Material Science and Engineering has developed a machine learning-based acoustic sensor for speaker recognition. Acoustic sensors were spotlighted as one of the most intuitive bilateral communication devices between humans and machines. However, conventional acoustic sensors use a condenser-type device for measuring
By slightly changing the body’s own molecules using a small inhaler, certain migraine patients can either cut down on medication or do without it completely. This is shown by a pilot study which has been published in the scientific journal Cephalalgia. Patients who suffer from migraine with aura, which is where they experience either sensory
This morning BlackBerry launched a new “Enterprise of Things” (EOT) platform called the BlackBerry Spark, as well as a slew of new healthcare related-products that will be powered by the system including a quantum-resistant code signing server, a new system that uses blockchain to deliver medical data and an operating system for secure medical devices.
Why do so many successful women suffer from impostor syndrome? Psychologist reveals how females in powerful jobs feel they’re not good enough and fear being exposed as a ‘fraud’ Impostor syndrome is a condition affecting more and more successful women Sufferers of the condition view their work success as luck rather than ability Many believe
WEDNESDAY, Oct. 3, 2018 — The association of sleep duration with incident stroke varies by race and sex, according to a study published online Oct. 3 in Neurology. Megan E. Petrov, Ph.D., from the Arizona State University in Phoenix, and colleagues examined the correlation between reported sleep duration and incident stroke among 16,733 black and
Americans’ love affair with fast food continues, with one in every three adults chowing down on the fare on any given day. That’s the finding from a new report from the U.S. Centers for Disease Control and Prevention. When asked by researchers, 37 percent of adults said they’d eaten fast food at least once over
Simulations with animal models meant to mirror galactic cosmic radiation exposure to astronauts are raising red flags for investigators at Georgetown University Medical Center (GUMC) about the health of astronauts during long voyages, such as to Mars. Their most recent study, published in the Proceedings of the National Academy of Sciences (PNAS), suggests that deep
Contrary to popular belief, the brain is not a computer. However brains do, in their own way, compute. They integrate informational inputs to generate outputs, including behaviors, thoughts, and feelings. To process vast amounts of data, the brain uses a kind of digital code. Its cells produce discrete bursts of electric current, known as action
For Emma Stone, her battle with anxiety and panic attacks has been a lifelong struggle. The actress, 29, spoke openly about her struggle with mental health that started with her first panic attack at 7 years old. “After first grade before I went into second grade, I had my first panic attack. It was really,
While planning a post-graduation trip with college friends, Loyola University Chicago senior Anna Wassman was totally focused on saving for her trip — until she noticed a lump in her right breast that she had definitely not felt before. A former professional ballerina who’s “very in tune with her body,” Wassman immediately called her doctor, who told
Cancer needs energy to drive its out-of-control growth. It gets energy in the form of glucose, in fact consuming so much glucose that one method for imaging cancer simply looks for areas of extreme glucose consumption — where there is consumption, there is cancer. But how does cancer get this glucose? A University of Colorado
If you’re one of the millions of women who get UTIs on the reg, listen up: you probably haven’t been drinking enough water. According to a new study, staying hydrated is the key to keeping your nether regions infection-free. Researchers from the University of Miami Miller School of Medicine recruited 140 women who suffer from
Crops such as wheat and maize have undergone a breeding process lasting thousands of years, in the course of which humankind has gradually modified the properties of the wild plants in order to adapt them to his needs. One motive was, and still is, higher yields. One “side effect” of this breeding has been a
A New Jersey man died after contracting a "brain-eating" amoeba called Naegleria fowleri, according to news reports. Though it's unclear exactly how the man, 29-year-old Fabrizio Stabile, got the amoeba, the Centers for Disease Control and Prevention (CDC) is currently investigating BSR Cable Park's Surf Resort in Waco, Texas, the Waco Tribune-Herald reported on Sept.