7 Uses for Spironolactone – From Heart Failure to Female Pattern Hair Loss

How does spironolactone work for so many conditions?

When it comes to the heart, lowering blood pressure, and helping relieve edema, spironolactone works by competing with aldosterone for receptor sites in the kidneys, which increases sodium and water removal while conserving potassium. That’s why it is called a potassium-sparing diuretic.

Wait, but what else?

When it comes to excess hair growth, acne and female pattern hair loss, spironolactone also works because it blocks androgen (male hormone) receptors and weakly inhibits androgen synthesis.

7 ways to use spironolactone

Here are seven conditions for which spironolactone at different doses can help:

Spironolactone is not for everyone. Women of reproductive age need to be aware that it should not be used during the first trimester of pregnancy. Anti-male hormone effects of spironolactone have been shown to cause feminization of the male fetus in animal studies.

Dr O.

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