Two children born after Transplantation of uterus

It is a Premiere in Germany: Two women who had been born without a uterus, brought to a successful Transplantation and now his own children to the world. The babies had been delivered in March and may 2019 by caesarean section, was announced by the University hospital of Tübingen.

“I’ve seen a lot of births, but caesarean section was an incredible Moment,” said Sara Brucker, the medical Director at the Institute for women’s health in Tübingen. She had accompanied the two women for a long time, you Wombs transplanted had previously been discounted.

In both cases, the mothers of the women were the organ donors. In one case, the mother had donated her Uterus in October 2016, and her then 23-year-old daughter. It was the first successful transplant of this organ in Germany. After the surgery scars had healed, the young patient is an egg used words that had been fertilized with the sperm of her husband. In may of this year, her healthy son was born.

No Chance of a biological child without organ donation

To the transplants in Tübingen, also Doctors from Sweden were involved, which are considered to be pioneers in the field of uterus Transplantation. In Sweden, a Baby was come 2014 for the first Time after a uterus transplant to the world. Meanwhile, globally, there were approximately 40 transplants of this kind, with more than 10 births. In South America, a woman brought in last year, the first child after a Uterus transplant from a deceased donor to the world. In the German-speaking area this type of Transplantation is performed only in the context of research projects.

The transplant team in Tübingen

“These are the first two successful pregnancies after uterine Transplantation in Germany and even within the eight European countries work together in the framework of Eurotransplant for organ donation and Transplantation,” said Xavier Rogiers, head of the transplant centre at the University hospital of Ghent. He stated that Uterus Transplantation will play a lasting role in the treatment of congenital infertility. However, from an ethical point of view, it is important to find a balance between the risks for the live donor and the offered a Chance for the recipient, so the expert.

Urban Wiesing, Director of the Institute for ethics and history of medicine at the University of Tübingen provides ethical arguments for the transplant. Living donation is justified for life-threatening diseases, but to alleviate the Suffering in the case of serious diseases. “For many women, it is very important to give birth to a child of their own, those suffering from her infertility,” says Wiesen.

“I’m more skeptical and think that the Uterus transplant for a non-proportionate means to allow a woman a pregnancy,” says Claudia Bozzaro by the Institute for ethics and history of medicine in Freiburg, Germany. You gave to remember that there are other ways to fulfill a desire to have children, for example Adoption.

The new mothers had been born due to a genetic disease, the so-called Mayer-Rokitansky-Küster-Hauser syndrome, without a uterus. A genetically own child, you would have had without medical intervention do not get it. Ovaries, Breasts, clitoris and labia are formed in this disease normal, a vagina, however, is not created. In a previous intervention, the Doctors had created in the vagina by the patient, therefore, is already to be had only at a later stage you are audited you with the uterus transplant.

For the artificial insemination of the women are no longer required cycles according to the Doctors, than the average. A fertilization in a natural way would not have been possible, because the women have no fallopian tubes. Overall, the pregnancies are going well. As with all patients who have received an Organ donated, you must also take the two women to drugs that suppress your immune system. However, these had no influence on the pregnancy.

The two mothers will keep their transplant organs for the time being – to hope for further success, said a spokesman for the clinic in Tübingen.