What is Elastin?

Elastin is an extracellular matrix protein that lends elasticity and resilience to tissues such as the arteries, lungs, tendons, skin, and ligaments. Elastic fibers have two components, one of which is encoded by the ELN gene. This protein has a high proportion of hydrophobic amino acids like glycine and proline, forming mobile hydrophobic domains. ELN

Peyronie's Disease Symptoms

Peyronie’s disease is epitomized by fibroblast proliferation in the tunica albuginea (a fascial structure in the penis), giving rise to a thick fibrous plaque that may result in pain, pathological penile curvature, as well as erectile dysfunction. Although trauma is considered a major causative factor, it is unlikely to be the sole culprit. The exact

Causes of Nocturnal Awakenings

Insomnia is a very common sleep disorder, and presents in various types. However, sleep maintenance insomnia (SMI) is the most frequent complaint. Both the cause of awakening and the difficulty in returning to sleep are important in precipitating episodes of nocturnal sleep disturbances. Research seems to suggest that hyperarousal states, personality traits, and physiologically determined

Hematidrosis Causes

Hematidrosis, also known as hematohidrosis, is a very rare phenomenon in which the individual sweats blood, or blood-tinged sweat exudes from the skin. It is also called hematofolliculohidrosis because of the appearance of blood along with sweat from the openings of the sweat glands. This latter term was coined by Manonukul and his colleagues in

ADHD and Depression

Attention deficit hyperactivity disorder, or ADHD, is a disorder that begins in childhood. It usually persists for years and results in significant deficits in cognitive, academic and social development. it is found to occur in about 3-7% of children, and persists in 36-60% of them into adulthood for an overall adult prevalence of about 4.5%.

Heart Disease Biomarkers and Screening Tests

By Gaea Miranda, BA Cardiovascular or heart diseases are the leading cause of death worldwide, with continuously increasing mortality rates continuously increasing due to the aging population. As such, it is a priority of key players in the field of medicine to detect early symptoms of such conditions and provide an empirically-based profile of heart

Top-Down Approach Overview

The top-down approach to systems biology reconstructs metabolic networks through data such as proteomics and transcriptomics. Credit: VectorFrenzy/Shutterstock.com It contrasts with the bottom-up approach, which also constructs biological pathway information associated with physiological processes. The top-down approach has historically been utilized in early genome sequencing methodologies and is now being employed in further detailing the

Why Do Older Women Lose their Libido (and How to Get it Back)?

Skip to: Why do Older Women Have a Reduced Libido? Is Reduced Libido a Matter of Concern? How to Regain Sexual Desire? Concept of low libido. Image Credit: Pavlovska Yevheniia / Shutterstock Elderly women generally have a lower sexual desire or libido because of age-related physiological, psychological, and social transition. Although libido reduces gradually with

Optimizing Protein Purification with FPLC

By Jeyashree Sundaram, MBA Fast protein liquid chromatography (FPLC) is a liquid chromatography technique for separation of protein molecules under pressure. It differs from high performance liquid chromatography in that the pressures are generally lower, around 435 to 580 psi, compared to 3000-to 5000 psi for an HPLC system. Credit: 7th Son Studio/ Shutterstock.com In

Relapsing-Remitting Multiple Sclerosis Symptoms

People with RRMS suffer may stay symptom-free for a period of time, only to end up with worsening symptoms when the next attack of MS hits them. New symptoms may also show up with every fresh relapse, which were not present before. The symptoms and severity of MS differs from individual to individual. Credit: Africa

Edge Resection Technique for Labiaplasty

Labial reduction is a term used to describe any surgical procedure that is intended to reduce the size and volume of the labia minora. The criteria for labial reduction are either functional or aesthetic, though in the majority of cases the latter is predominant. This is ironic in view of the fact that the ideal

Meningitis Research

Meningitis is a term which refers to the inflammation of the meninges, the membranes that surround and protect the brain and spinal cord. Credit: Jarun Ontakrai/Shutterstock.com Meningitis typically occurs due to a bacterial or viral infection, but other conditions are sometimes responsible, including fungal or parasitic infection, certain autoimmune inflammatory conditions, trauma, or drug reactions.

Somatization Symptoms

Somatization refers to the expression of psychological or emotional problems as physical (somatic) symptoms. A common example is a headache being brought on by stress. Credit: Yuttana Jaowattana/ Shutterstock.com Somatization can give rise to a group of disorders broadly referred to as the somatoform disorders, which may be characterized by chronic and severe symptoms. People

The i-motif in DNA

Cytosine rich DNA sequences can fold into a structure called an i-motif. These structures typically appear in promoter regions on DNA, and are thought to help with gene regulation. An artist's impression of the i-motif DNA structure inside cells, along with the antibody-based tool used to detect it. Image Credit: Chris Hammang / Shutterstock Around

Quorum Sensing and Vibrio Cholerae

Quorum sensing is a phenomenon in which bacteria can communicate with members of their own species and other species to coordinate their behavior. This phenomenon is achieved by the production and sensing of secreted signal molecules, which diffuse from the microbial cells and build up in the environment. Quorum sensing allows for bacteria to coordinate

Carcinogens in Cigarette Smoke

Lung cancer is still the leading cause of death in both men and women around the world, killing more than one million people every year. Extensive epidemiological data clearly links cigarette smoking with lung cancer, mostly due to the presence of cancer-causing chemicals called carcinogens that are present in present in cigarette smoke. YAKOBCHUK VIACHELSLAV

Hybrid Capture-Based Human Papillomavirus Detection

Human papillomavirus (HPV) infection is the major cause of cervical cancer. Hybrid capture based human papillomavirus detection is a test that can detect different types of human papillomavirus, which is used to detect high-grade cervical lesions. Human Papillomavirus. Image Credit: Liya Graphics / Shutterstock Human Papillomavirus and Cervical Cancer Human papillomavirus (HPV) is a common

What are Cyclin-Dependent Kinases?

Cyclin-dependent kinases are a type of serine/threonine kinase which are activated by cyclins to drive the progress of the cell cycle. The cell cycle is a comprised of 4 stages, which are tightly controlled to ensure accurate replication of DNA and formation of daughter cells. Each of these stages is accompanied by an increase in