Genetically manipulating protein level in colon cancer cells can improve chemotherapy

Colorectal cancer outcomes may improve by genetically altering an immune-regulatory protein in cancer cells, making the cells more vulnerable to chemotherapy. That’s according to new Mayo Clinic research. The findings, published this month in Oncogene, indicate that increasing the expression of the PD-L1 protein in colorectal cancer cells can improve the effectiveness of chemotherapy. “These

Starbucks' New Pumpkin Cream Cold Brew Is Even Better the PSL

The return of the PSL marks the start of fall for Starbucks lovers, despite falling well before the official first day of autumn. Since it’s still too hot to comfortably drink a hot latte—and because cold beverages accounted for 50 percent of the coffee giant’s sales in 2018—Starbucks is giving fans a new pumpkin drink

How the brain ‘approximates’ without actually counting

From the time of early infancy, humans are endowed with the capacity to approximate the number of objects in their visual field, an ability that continues throughout life and may underlie the development of more complex mathematical skills. For years, scientists have explored how people estimate numerical quantities without physically counting objects one by one,

Childhood cancer survivors at elevated risk of heart disease

Survivors of childhood cancer have a higher risk of developing a range of heart disease due to cancer therapy, according to new research published in the American Heart Association’s journal Circulation. Most studies of this survivor group have focused on heart failure related to anthracyclines, a class of chemotherapy medications used to treat many types

Teacher training needed to help students with ADHD

Better training for teachers to understand ADHD and how to deal with it in the classroom is more important than targeted funding to support the student at school, ADHD experts say. Parents overwhelmingly believe teachers and key staff need professional development and training to better support children with attention deficit hyperactivity disorder (ADHD), according to

How to tell if your teen is depressed

Teen depression is a serious mental health problem that causes a persistent feeling of sadness and loss of interest in activities. It affects how your teenager thinks, feels and behaves, and it can cause emotional, functional and physical problems. Although depression can occur at any time in life, symptoms may be different between teens and

New vaccine targets killer disease tuberculosis

There is only one existing vaccine for TB and it is not effective in adults. Researchers at the Centenary Institute and University of Sydney will next test their new vaccine in clinical trials with humans. Australian medical researchers from the Centenary Institute and the University of Sydney have successfully developed and tested on mice a

Certain metabolites linked to stem cell function in the intestine: Molecules called ketone bodies may improve stem cells’ ability to regenerate new intestinal tissue

MIT biologists have discovered an unexpected effect of a ketogenic, or fat-rich, diet: They showed that high levels of ketone bodies, molecules produced by the breakdown of fat, help the intestine to maintain a large pool of adult stem cells, which are crucial for keeping the intestinal lining healthy. The researchers also found that intestinal

Computer model could help test new sickle cell drugs

A team of Brown University researchers has developed a new computer model that simulates the way red blood cells become misshapen by sickle cell disease. The model, described in a paper published in Science Advances, could be useful in the preclinical evaluation of drugs aimed at preventing the sickling process. “There are currently only two

Nope, 'Mommy-&-Me' Outfits Aren't Just For Girls

These days, it feels like adorable mother-daughter matching outfits are everywhere. From chic dresses to tiny bikinis to trendy rompers, even down to matching floral headbands, the mommy-and-me matchy-matchy girly-girly options are seemingly endless. But mother-son outfits? Where on earth are they?? Yeah, it’s hard to be a mom of boys when you’ve got a