Tag: antibody

Current monoclonal antibodies less potent against SARS-CoV-2 variants

The coronavirus disease (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to wreak havoc across the globe. Scientists are racing to develop effective therapeutic regimens to combat the infection. One of therapy currently used to stimulate a robust immune response against the virus is monoclonal antibodies, a treatment used for

Immune response to SARS-CoV-2 may be limited by a set of genes

Neutralizing antibodies develop within two weeks of a SARS-CoV-2 infection, but their durability and intensity can vary by individual, prompting concerns about the prospects of long-lasting immunity and efficacy of COVID-19 vaccines. In a PLOS ONE paper, published online February 11, 2021, researchers at University of California San Diego School of Medicine report that individual

Detection of emerging SARS-CoV-2 variant in New York

Researchers at the California Institute of Technology in Pasadena have developed a software tool called "Variant Database" that has detected an emerging lineage of severe acute respiratory coronavirus 2 (SARS-CoV-2) isolates in New York. The novel SARS-CoV-2 virus is the agent responsible for the coronavirus disease 2019 (COVID-19) pandemic that continues to sweep the globe

SARS-CoV-2 evolves antibody resistance in immunocompromised patient

Researchers in the United States who tracked the evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an immunocompromised patient found that convalescent plasma therapy was associated with the emergence of viral variants that were less susceptible to neutralizing antibodies. The SARS-CoV-2 virus is the agent responsible for the coronavirus 2019 (COVID-19) pandemic that

Study finds low SARS-CoV-2 antibody responses in asymptomatic and mild COVID-19 cases

The coronavirus disease 2019 (COVID-19) pandemic continues to spread across the globe. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the disease exhibits an array of clinical outcomes (from asymptomatic to critical). The majority of cases are asymptomatic or minimally symptomatic, wherein there are no symptoms or only a few manageable ones.

What is iDISCO?

Visualizing Structures within Tissue To see structure within biological tissue such as organs, it is necessary to first label the tissue. Antibodies are frequently used for this purpose, and this is known as “immunolabelling”. iDISCO: Adult mouse kidney, screen capture via https://www.youtube.com/watch?v=HCdSCMlNafk Antibodies are specific to certain “markers”, or antigens, and immunolabelling is used for

Type of Pollen Allergies

Skip to: How allergies usually work? Types of Pollen Allergies Diagnosis of Pollen Allergies How to Treat Pollen Allergies? Pollen grains are released by trees, flowers and other plans with to fertilize other plants of the same species. An allergy to pollen is one of the most allergic reactions is the USA. Studies show that

Benefits of Multiplex Immunoassays

How do you multiplex an immunoassay? There are two main ways of multiplexing an immunoassay; by separating the individual assays into different spaces (spatial separation) or by immobilizing antibodies onto different beads based on what they target. Jarun Ontakrai | Shutterstock Spatial separation is typically achieved by placing antibodies in different parts of a shared

Preclinical data on lead coronaviruses antibody

Adagio Therapeutics today published in vitro and in vivo data in Science on its lead antibody candidate, ADG2, which demonstrated similar or higher potency against SARS-CoV-2 compared to other monoclonal antibodies (mAbs) in clinical development and strong binding to all known SARS-CoV-2 variants. Uniquely, ADG2 also showed broad and potent neutralization against a range of

Researchers collaborate on universal antibody test for COVID-19

Researchers with the U.S. Army Futures Command are part of a team that tested alternative ways to measure COVID-19 antibody levels, resulting in a process that is faster, easier and less expensive to use on a large scale. Their method holds promise for accurately identifying potential donors who have the best chance of helping infected

I was the family guinea pig for a new Covid antibody test

‘I was the family guinea pig for a new Covid antibody test’: SUE REID and SIMON WALTERS undergo coronavirus tests Here’s how to help people impacted by Covid-19 Antibody tests, which reveal whether you’ve had Covid-19, have been hailed as the way out of lockdown and safely getting people back to work.  With one of the

Positive outcome for Hendra antibody trial

A process developed by University of Queensland researchers to produce larger quantities of the Hendra virus therapeutic antibody could be expanded to manufacture treatments for other potentially deadly viruses around the world. Researchers at UQ’s Australian Institute for Bioengineering and Nanotechnology (AIBN) used this process to produce material for Queensland Health’s world-first human Hendra virus