Tag: arthritis

Arthritis symptoms: Four unusual signs of rheumatoid arthritis

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Societies Issue Joint Statement on Safe Use of HCQ

Hydroxychloroquine can be used safely and effectively with attention to dosing, risk factors, and screening, but communication among physicians, patients, and eye care specialists is key to optimizing outcomes and preventing complications, according to a joint statement from four medical societies. The American College of Rheumatology, American Academy of Dermatology, Rheumatologic Dermatology Society, and the

Obesity and Urinary Incontinence

Obesity and urinary incontinence are both common disorders. The prevalence of obesity is on the rise worldwide with a 6% increase per year in the United States. Obesity Over half of American women are overweight (BMI 25 to 29.9 kg/m2) or obese (BMI 30 kg/m2 or greater). Obesity is associated with several health conditions including

How to talk to your doctor about arthritis pain

Chronic pain can be excruciating, debilitating and hard to describe. Yet the best way to get the right treatment for the exact pain you’re experiencing is to put those symptoms into words, so your doctor can pinpoint a diagnosis and help you find relief. The Arthritis Foundation created a guide with suggestions for communicating your

Newer Rheumatoid Arthritis Drug, Upadacitinib (Rinvoq), May Help Ease Tough-to-Treat Cases

MONDAY, Oct. 19, 2020 — A recently approved rheumatoid arthritis medication appears to be an effective second-line therapy when biologic treatments start to fail, a new clinical trial reports. Arthritis sufferers treated with upadacitinib had a significantly greater reduction in their symptoms and disease activity than people treated with a standard disease-modifying antirheumatic drug (DMARD),

Lilly's rheumatoid arthritis drug cuts COVID-19 deaths in trial,…

Arthritis drug improves survival odds for COVID-19 patients treated with remdesivir by 35%, NIH study finds An NIH trial tested a combination of Eli Lilly’s arthritis drug, barcitinib, and the antiviral  remdesivir to treat COVID-19  Overall, those who got both drugs were 35% more likely to survive than those given remdesivir alone  People on supplemental

Early therapy for rheumatoid arthritis may slow heart disease

(HealthDay)—Disease-modifying antirheumatic drug (DMARD) therapy for rheumatoid arthritis (RA) treatment also cuts cardiovascular disease (CVD) risk, according to a study published online Aug. 28 in the Annals of the Rheumatic Diseases. Sven Plein, M.D., Ph.D., from the University of Leeds in the United Kingdom, and colleagues randomly assigned 81 patients with early RA to either

New pieces added to the molecular puzzle of rheumatoid arthritis

Walter and Eliza Hall Institute researchers have revealed new details about how joint inflammation evolves in rheumatoid arthritis, and the cells that prolong the inflammatory attack. In both laboratory models and human clinical samples, the research team pinpointed immune cells called natural killer (NK) cells as an unexpected source of the inflammatory protein GM-CSF in

Osteoarthritis linked to higher risk of dying from cardiovascular disease

Researchers at Lund University in Sweden have investigated the link between osteoarthritis and mortality in an epidemiological study. It was shown that the risk of dying from cardiovascular disease was higher for people with osteoarthritis than for the rest of the population. Using population registers, the researchers studied approximately 469,000 people living in Skåne, Sweden,

A deep-dive into the impact of arthritis drugs on gene expression

A new computational framework has revealed key differences between four rheumatoid arthritis medications and their impact on biological pathways in mice. Niki Karagianni of Biomedcode Hellas SA, Greece, and colleagues present their new approach and findings in PLOS Computational Biology. People with rheumatoid arthritis often receive medications that target and inhibit Tumor-Necrosis Factor (TNF), a

Rheumatoid arthritis drug diminishes Zika birth defects in mice

In experiments with pregnant mice infected with the Zika virus, Johns Hopkins Medicine researchers report they have successfully used a long-standing immunosuppressive drug to diminish the rate of fetal deaths and birth defects in the mice’s offspring. The U.S. Food and Drug Administration-approved medicine, anakinra, once commonly used to treat rheumatoid arthritis and other autoimmune