Tag: Biology

A study of rat brain slices published in JNeurosci demonstrates how nicotine interacts with cells that regulate the output of a brain region involved in habit formation. The research could inform efforts to help people quit smoking and avoid relapse. The addictive qualities of nicotine have been attributed to the brain’s reward system. However, recent

Focal adhesions are large specialized proteins that are located in the area where a cell membrane meets the extracellular matrix (ECM), a collection of molecules surrounding the cells that provide support and regulate micromechanical signals to the cells. Examining focal adhesions is one of the key elements to understanding how a cell proliferates, differentiates, and

Smoking tobacco from a waterpipe, also known as a hookah, accounted for over half of the tobacco smoke volume consumed by young adult hookah and cigarette smokers in the U.S., a new University of Pittsburgh School of Medicine analysis discovered. Toxicant exposures — such as tar, carbon monoxide and nicotine — were lower, yet substantial,

A team of researchers led by Dr. Catharine Winstanley at the University of British Columbia have uncovered a network of regions in the brain that are involved in determining the choice of working harder to get a bigger reward, or putting in a lesser effort and receiving a smaller reward. Understanding how the brain makes

A new study has discovered that horses were first domesticated by descendants of hunter-gatherer groups in Kazakhstan who left little direct trace in the ancestry of modern populations. The research sheds new light on the long-standing “steppe theory” on the origin and movement of Indo-European languages made possible by the domestication of the horse. The

Meadowfoam, a native Pacific Northwest plant cultivated as an oilseed crop, has emerged as a potential new source of protection against the sun’s harmful effects on the skin. The findings by scientists at Oregon State University are important because nearly 10,000 people a day in the United States are diagnosed with skin cancer, resulting in

A little-explored group of immune cells plays an important role in the regulation of intestinal bacteria. Changing metabolic states of the microbes have an effect on defense cells at different stages of alert or rest, as researchers from the Department of Biomedicine at the University and University Hospital of Basel report in the journal Mucosal

Plant scientists have taken the crucial last steps in a 60-year quest to unravel the complex chemistry of Madagascar periwinkle in a breakthrough that opens up the potential for rapid synthesis of cancer-fighting compounds. The team in the laboratory of Professor Sarah O’Connor at the John Innes Centre have, after 15 years of research, located

Our brains are home to a staggering 86 billion or so cells that are carefully woven into the structure that lets us think, feel and live. This awe-inspiring complexity offers a glimpse into why, after many years of research, there’s still so much to be understood about the brain. And for brain tumours, the unknowns

Researchers have provided new insight into the cellular processes behind the ‘shock and kill’ approach to curing HIV, which they say challenges the effectiveness of the treatment. Their study, published in the journal eLife, suggests the need to explore alternative treatment strategies against HIV — a virus which 36.7 million people globally were living with

What happens in a cell when genetic information is translated into proteins? In order to study this process, researchers take a closer look on one particular biomolecule inside the cell: messenger ribonucleic acid, mRNA for short. This biomolecule plays a major role in all cellular processes — and it is also the focus of joint

Researchers today generally agree that eating garlic, used for thousands of years to treat human disease, can reduce the risk of developing certain kinds of cancers, cardiovascular disease, and type 2 diabetes. Nevertheless, in a review published April 26 in the journal Trends in Pharmacological Sciences, researchers in the UK argue that explaining exactly how

Although cannabis, also known as marijuana, has been shown to impair memory, reaction time and attention, it is difficult to assess this impairment in a natural setting. Researchers have developed a prototype app called ‘Am I Stoned’ that could help cannabis users understand how the drug is affecting them through a series of phone-based tasks.

It’s DNA, but not as we know it. In a world first, Australian researchers have identified a new DNA structure — called the i-motif — inside cells. A twisted ‘knot’ of DNA, the i-motif has never before been directly seen inside living cells. The new findings, from the Garvan Institute of Medical Research, are published

An international team of scientists including the University of Adelaide has discovered a new complex carbohydrate in moss that could possibly be exploited for health or other uses. The scientists, from Australia’s ARC Centre of Excellence in Plant Cell Walls and University of Rhode Island, in the US, say the polysaccharide looks a bit like

A new study from McMaster and York universities has found that poor muscle health may be a complication of Type 1 diabetes, even among active twenty-somethings. The research team analyzed muscle biopsies of young adults with and without Type 1 diabetes who exceed Diabetes Canada’s recommended weekly levels for physical activity. The researchers found structural

In the early days of neuroscience research, scientists painstakingly stained brain cells and drew by hand what they saw in a microscope. Fast forward to 2018 and machines may be able to learn how to do that work. According to a new study in Cell, it may be possible to teach machines how to pick

Researchers at the University of Michigan Life Sciences Institute and the Howard Hughes Medical Institute have determined how satellite DNA, considered to be “junk DNA,” plays a crucial role in holding the genome together. Their findings, published recently in the journal eLife, indicate that this genetic “junk” performs the vital function of ensuring that chromosomes

The genetic basis of lifespan determination is poorly understood. Most research has been done on short-lived animals, and it is unclear if these insights can be transferred to long-lived mammals like humans. By comparing genes of long- and short-lived rodents, researchers from Leibniz Institute on Aging (FLI) in Jena/Germany now identified in a collaborative project