Tag: Bone Marrow

Mesenchymal stem cells (MSCs) are thought to have great potential in the field of regenerative medicine, which has the aim of restoring damaged tissues. However, not much was known about in vivo plasticity of them—until now. Researchers have identified a subpopulation of MSCs that promote the healing of bone fractures and show an enhanced ability

People with rare disorders that cause shortened telomeres — protective caps that sit at the end of chromosomes — may be more likely to have blood cancers such as leukemia or myelodyplastic syndrome. Now, Johns Hopkins Medicine scientists have discovered several "self-correcting" genetic mutations in bone marrow that may protect such patients from these cancers.

Shortage of hematologists or specialists to treat blood disorders in Africa requires urgent action, experts say. The acute shortage of hematologists in Sub-Saharan Africa has given rise to an urgent need for training to help address increasing cases of blood disorders, scientists say. The World Health Organization (WHO) recommends one clinical hematologist per 100,000 people

Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient's own blood-forming stem cells. The trial will combine CRISPR technology developed at Innovative Genomics

Researchers from Uppsala University show in a new study that inhibition of the protein EZH2 can reduce the growth of cancer cells in the blood cancer multiple myeloma. The reduction is caused by changes in the cancer cells' metabolism. These changes can be used as markers to discriminate whether a patient would respond to treatment

Anemia is due to lack of haemoglobin in the blood which is below the normal level or due to less than normal levels of red blood cells in blood. The haemoglobin helps carry oxygen in blood. Lack of haemoglobin thus causes deficiency of life giving oxygen to vital organs. (1-4) Types of anemia There are

Swollen or affected lymph nodes may sometimes need to be removed for examination. This is called lymph node biopsy. Lymph node biopsy A biopsy involves removal of whole or part of the lymph node to look under the microscope for signs of infection, or cancer. Lymph nodes are filters located at intervals between the lymph

Century long-overlooked network of blood vessels The organs of the human body are widely known – one would think. However, a German research team recently discovered a previously unknown System of fine blood vessels within our bones, that connects the bone marrow with the bone skin. Researchers from the University of Duisburg-Essen (UDE), of the