Tag: Brain Injury

Contrary to popular belief, the brain is not a computer. However brains do, in their own way, compute. They integrate informational inputs to generate outputs, including behaviors, thoughts, and feelings. To process vast amounts of data, the brain uses a kind of digital code. Its cells produce discrete bursts of electric current, known as action

Spinal cord stimulation and physical therapy have helped a man paralyzed since 2013 regain his ability to stand and walk with assistance. The results, achieved in a research collaboration between Mayo Clinic and UCLA, are reported in Nature Medicine. With an implanted stimulator turned on, the man was able to step with a front-wheeled walker

Zombie cells are the ones that can’t die but are equally unable to perform the functions of a normal cell. These zombie, or senescent, cells are implicated in a number of age-related diseases. And with a new letter in Nature, Mayo Clinic researchers have expanded that list. In a mouse model of brain disease, scientists

Someday doctors may prescribe sugar pills for certain chronic pain patients based on their brain anatomy and psychology. And the pills will reduce their pain as effectively as any powerful drug on the market, according to new research. Northwestern Medicine scientists have shown they can reliably predict which chronic pain patients will respond to a

Ever wonder why some people seem to feel less pain than others? A study conducted at Wake Forest School of Medicine may have found one of the answers — mindfulness. “Mindfulness is related to being aware of the present moment without too much emotional reaction or judgment,” said the study’s lead author, Fadel Zeidan, Ph.D.,

Researchers have found that women who play soccer may be more at risk than their male counterparts. According to a new study published in the journal Radiology, female soccer players exhibit more extensive changes to brain tissue after repetitive ‘heading’ of the soccer ball. Soccer is the most popular competitive sport in the world, and

When a muscle is acutely injured — whether through accidental strain or intentional weight lifting — special repair cells called fibro-adipogenic progenitors (FAPs) rush to the rescue. These cells coordinate the activity of the immune system and muscle stem cells to replace and repair the torn tissue. Now, scientists at Sanford Burnham Prebys Medical Discovery

The cerebral cortex is a highly developed brain region, which allows intellectual functions such as conscious perception, anticipation of events and language. These functions are mediated by specific sets of neuronal circuits. To understand how these circuits emerge during development, researchers from the University of Geneva (UNIGE), Switzerland, in collaboration with an American team, investigated

A deadly feature of acute lymphoblastic leukemia (ALL) is its invasion of the central nervous system. ALL in the central nervous system is very difficult to treat, because most drugs are blocked from the organ system due to a “blood-brain barrier” designed to protect the brain. How cancer cells enter the central nervous system has

Patients with persistent facial pain are costing the economy more than £3,000 each per year, new research has revealed. Experts at Newcastle University, UK, say introducing an electronic referral system to speed up diagnosis and treatment is likely to improve quality of life and save money. The team has assessed the hidden costs of people

Being aware of our surroundings is a fundamental aspect of our existence. But what in our biological makeup determines how we access and interpret the endless stream of information around us? A new Tel Aviv University study published in Current Biology suggests that noradrenaline, a neurotransmitter responsible for arousal in the brain, plays a vital

Researchers from the University of Michigan found that serum levels of two biomarkers of traumatic brain injury, tau and ubiquitin C-terminal hydrolase L1, are elevated following high-acceleration head impacts, even when there is no clinical diagnosis of concussion. Their complete findings are reported today in the Journal of Neurosurgery, in the article “Elevated markers of

A study of rat brain slices published in JNeurosci demonstrates how nicotine interacts with cells that regulate the output of a brain region involved in habit formation. The research could inform efforts to help people quit smoking and avoid relapse. The addictive qualities of nicotine have been attributed to the brain’s reward system. However, recent

A team of researchers at Johns Hopkins have found that activating nerve cell receptors along two chemical pathways — one that has previously been linked to how the brain senses “itch” — may improve pain relief when combined with conventional ways to blunt pain using opioid drugs, such as morphine. The study results, published in

Our eye hosts a powerful biological computer, the retina. Understanding how the retina transforms images from the outside world into signals that the brain can interpret would not only result in insights into brain computations, but could also be useful for medicine. As machine learning and artificial intelligence develop, eye diseases will soon be described

Anxious people take fewer risks — this is not surprising. However, a team of psychologists from the German Friedrich Schiller University Jena, together with partners from Würzburg in Germany and the Canadian University of Victoria have succeeded in making this decision process visible in the brain, allowing them to predict the behaviour of individuals. They

New preclinical research shows a gene already linked to a subset of people with autism spectrum disorder is critical to healthy neuronal connections in the developing brain, and its loss can harm those connections to help fuel the complex developmental condition. Scientists at Cincinnati Children’s Hospital Medical Center report in Developmental Cell their data clarify

Memories of traumatic experiences can lead to mental health issues such as post-traumatic stress disorder (PTSD), which can destroy a person’s life. It is currently estimated that almost a third of all people will suffer from fear- or stress-related disorders at one point in their lives. Now, a new study shows — at the cellular

New findings from the long-running Whitehall II study of over 10,000 civil servants has found 50-year-olds who had blood pressure that was higher than normal but still below the threshold commonly used when deciding to treat the condition, were at increased risk of developing dementia in later life. This increased risk was seen even when

The coordination of neural activity across widespread brain networks is essential for human cognition. Researchers have long assumed that oscillations in the brain, commonly measured for research purposes, brain-computer interfacing, and clinical tests, were stationary signals that occurred independently at separate brain regions. Biomedical engineers at Columbia Engineering have discovered a new fundamental feature of