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Recruitment of miR-8080 by luteolin inhibits AR-V7 in castration-resistant prostate cancer

Prostate cancer is the most common noncutaneous malignancy in the United States and is responsible for many male deaths. The development of prostate carcinogenesis is initially androgen-dependent. However, the progression of castration-resistant prostate cancer (CRPC) following androgen deprivation therapy is a major clinical problem. Although enzalutamide and abiraterone have been approved for CRPC hormone therapy,

Jamie Oliver Lost 26 Pounds By Making 2 Changes

Celebrity Chef Jamie Oliver lost 26 pounds recently without going on a drastic diet. Instead, Oliver made two simple dietary changes, according to UK outlet, Express. “I lost 12 kilos quite quickly and I didn’t do it through not eating,” he explained in the outlet. First, he traded meat for nuts to meet his fat

Healthcare challenges faced by transgender people of color

Transgender people who are also racial and ethnic minorities have a difficult time finding a healthcare setting where all aspects of their identity are welcome, understood and addressed. In a new study published in the October issue of the Journal of General Internal Medicine, a research team from the University of Chicago Medicine shows how

Philippines hit by first polio case since 2001

Credit: CC0 Public Domain The Philippines has detected its first case of polio since 2001, officials said Thursday, putting some of the blame on mistrust stoked by a dengue fever vaccine scandal. Health authorities said a three-year-old girl in a southern province had contracted polio, while the virus was also detected in Manila’s sewage and

Suicide risk factors vary by ethnic group

Approximately 8.3 million adults in the United States reported thinking about suicide last year, according to the Centers for Disease Control and Prevention. While thoughts and deeds are clearly different, University of Houston professor of psychology Rheeda Walker has examined both and finds that current approaches to suicide prevention are troubling, because they usually consist

IUDs lower women’s risk of developing ovarian cancer by 30%

IUDs can lower a woman’s risk of developing ovarian cancer by more than 30%, study finds Women who used intrauterine devices (IUDs) for birth control could lower their risk of ovarian cancer by between 15% and 32% The risk was mitigated whether women used hormonal or non-hormonal IUDs  Researchers believe it’s because IUDs combat estrogen, the hormone

Phase 1 study shows novel KRAS inhibitor well tolerated by patients with adenocarcinoma and non-small cell lung cancer

A clinical trial testing the toxicity of a KRAS inhibitor demonstrated early promising antitumor activity and few adverse side effects in patients with advanced non-small cell lung cancer harboring KRAS G12C mutation, according to research presented today at the IASLC 2019 World Conference on Lung Cancer, hosted by the International Association for the Study of

Preeclampsia risk may be reduced by a healthy high-fibre diet

A healthy diet rich in fibre is generally recommended, but new research shows it could be even more important during pregnancy to promote the wellbeing of the mother and child. Plant-based fibre is broken down in the gut by bacteria into factors that influence the immune system. Researchers from the University of Sydney’s Charles Perkins

‘Cannabis addiction’ gene has been discovered by scientists

‘Cannabis addiction gene’ that could make people more likely to abuse the drug is discovered by scientists in a ‘really important’ breakthrough Gene CHRNA2 regulates a ‘nicotine receptor’ in the brain, scientists have said  Low levels of this receptor has been linked to an increased of marijuana abuse Discovery could help medics treat and even

Tons Of People Swear By This Quick Fix For Gas And Bloating

If you’ve ever had a meal and felt uncomfortable for hours after—think bloating, indigestion, or cramping—you know how much it sucks. But what if you could pop a pill and finally have these issues become a thing of the past? Well, digestive enzyme supplements claim to banish bloat and cramping from gastrointestinal issues, so you